Haff disease laboratory findings: Difference between revisions
(→Overview: Added overview) |
Jose Loyola (talk | contribs) |
||
| (4 intermediate revisions by 3 users not shown) | |||
| Line 4: | Line 4: | ||
==Overview== | ==Overview== | ||
The diagnostic criteria for defining a case of Haff disease | The diagnostic criteria for defining a case of Haff disease include a history of consumption of cooked seafood within 24 hours prior to the onset of symptoms, elevated serum CPK, and CK-MB fraction of less than 5%. Evaluation of Haff disease should include CBC, creatine kinase, serum electrolytes, liver function test, urine pH, and urinalysis. | ||
Evaluation of Haff disease should include CBC, creatine kinase, serum electrolytes, liver function test, urine pH and urinalysis. | |||
==Laboratory findings== | ==Laboratory findings== | ||
| Line 21: | Line 19: | ||
<ref name="pmid31843046">{{cite journal| author=Pei P, Li XY, Lu SS, Liu Z, Wang R, Lu XC | display-authors=etal| title=The Emergence, Epidemiology, and Etiology of Haff Disease. | journal=Biomed Environ Sci | year= 2019 | volume= 32 | issue= 10 | pages= 769-778 | pmid=31843046 | doi=10.3967/bes2019.096 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=31843046 }} </ref> | Currently, the following diagnostic criteria is used to define cases of Haff disease:<ref name="pmid31843046">{{cite journal| author=Pei P, Li XY, Lu SS, Liu Z, Wang R, Lu XC | display-authors=etal| title=The Emergence, Epidemiology, and Etiology of Haff Disease. | journal=Biomed Environ Sci | year= 2019 | volume= 32 | issue= 10 | pages= 769-778 | pmid=31843046 | doi=10.3967/bes2019.096 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=31843046 }} </ref> | ||
#A history of consumption of cooked seafood within 24 hours prior to the onset of symptoms | #A history of consumption of cooked seafood within 24 hours prior to the onset of symptoms | ||
| Line 34: | Line 32: | ||
[[Category:Disease]] | [[Category:Disease]] | ||
[[Category:Syndromes]] | [[Category:Syndromes]] | ||
[[Category: | [[Category:Up to Date]] | ||
Latest revision as of 18:36, 9 May 2022
|
Haff disease Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Haff disease laboratory findings On the Web |
|
American Roentgen Ray Society Images of Haff disease laboratory findings |
|
Risk calculators and risk factors for Haff disease laboratory findings |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: M. Hassan, M.B.B.S
Overview
The diagnostic criteria for defining a case of Haff disease include a history of consumption of cooked seafood within 24 hours prior to the onset of symptoms, elevated serum CPK, and CK-MB fraction of less than 5%. Evaluation of Haff disease should include CBC, creatine kinase, serum electrolytes, liver function test, urine pH, and urinalysis.
Laboratory findings
Since Haff disease causes rhabdomyolysis, the approach to the evaluation of rhabdomyolysis should be as follows:
- CBC (complete blood count)
- Creatine kinase (three-five times the upper limit of normal values of 100 to 400 IU/L)[1]
- Chemistries (hyperkalemia, hyperphosphatemia, and hypocalcemia)
- Liver function test
- Urine pH
- Urinalysis
- Blood (+)
- No red blood cells on microscopy (seen in either hemoglobinuria or myoglobinuria)
Currently, the following diagnostic criteria is used to define cases of Haff disease:[2]
- A history of consumption of cooked seafood within 24 hours prior to the onset of symptoms
- Elevated serum creatine phosphokinase (more than fivefold)
- CK-MB fraction of <5%
References
- ↑ "StatPearls". 2022. PMID 28846335.
- ↑ Pei P, Li XY, Lu SS, Liu Z, Wang R, Lu XC; et al. (2019). "The Emergence, Epidemiology, and Etiology of Haff Disease". Biomed Environ Sci. 32 (10): 769–778. doi:10.3967/bes2019.096. PMID 31843046.