Haff disease natural history, complications and prognosis: Difference between revisions
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==Overview== | ==Overview== | ||
Haff disease has an incubation period of eight hours | Haff disease has an incubation period of eight hours and presents with nausea, vomiting, muscle rigidity, chest pain, diaphoresis, and brown urine. Though it is a self-limiting condition with a good prognosis, some cases may develop complications such as acute kidney injury and disseminated intravascular coagulation. | ||
==Natural history, Complications and Prognosis== | ==Natural history, Complications and Prognosis== | ||
As Haff disease is a rare clinical syndrome, it is oftentimes misdiagnosed. Early diagnosis and treatment are required to prevent the development of complications. | *As Haff disease is a rare clinical syndrome, it is oftentimes misdiagnosed. Early diagnosis and treatment are required to prevent the development of complications. | ||
It has an incubation period of eight hours | *It has an incubation period of eight hours and presents with nausea, vomiting, myalgias, muscle rigidity, chest pain (mimicking [[myocardial infarction]]), diaphoresis, dyspnea, and brown urine indicating [[myoglobinuria]]. As it is a self limiting condition with good prognosis, most patients recover in 2-5 days. Haff disease is rarely associated with mortality, but some cases may develop complications such as [[acute kidney injury]] and [[disseminated intravascular coagulation]]. <ref name="pmid25978748">{{cite journal| author=Diaz J| title=Don't be Half-Educated About Haff Disease in Louisiana. | journal=J La State Med Soc | year= 2015 | volume= 167 | issue= 1 | pages= 6-10 | pmid=25978748 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25978748 }} </ref> <ref name="pmid28846335">{{cite journal| author=| title=StatPearls | journal= | year= 2022 | volume= | issue= | pages= | pmid=28846335 | doi= | pmc= | url= }} </ref> | ||
==References== | ==References== | ||
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[[Category:Disease]] | [[Category:Disease]] | ||
[[Category:Syndromes]] | [[Category:Syndromes]] | ||
[[Category: | [[Category:Up to Date]] | ||
Latest revision as of 13:19, 27 April 2022
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: M. Hassan, M.B.B.S
Overview
Haff disease has an incubation period of eight hours and presents with nausea, vomiting, muscle rigidity, chest pain, diaphoresis, and brown urine. Though it is a self-limiting condition with a good prognosis, some cases may develop complications such as acute kidney injury and disseminated intravascular coagulation.
Natural history, Complications and Prognosis
- As Haff disease is a rare clinical syndrome, it is oftentimes misdiagnosed. Early diagnosis and treatment are required to prevent the development of complications.
- It has an incubation period of eight hours and presents with nausea, vomiting, myalgias, muscle rigidity, chest pain (mimicking myocardial infarction), diaphoresis, dyspnea, and brown urine indicating myoglobinuria. As it is a self limiting condition with good prognosis, most patients recover in 2-5 days. Haff disease is rarely associated with mortality, but some cases may develop complications such as acute kidney injury and disseminated intravascular coagulation. [1] [2]