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{{Small intestine cancer}}
'''For patient information click [[{{PAGENAME}} (patient information)|here]]'''
'''For patient information click [[{{PAGENAME}} (patient information)|here]]'''


{{CMG}}
{{CMG}}; {{AE}} {{Qurrat}}, {{PSD}}


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{{SK}} Small bowel cancer


==Overview==
{{Search infobox}}
[[Image:Duodenal adenocarcinoma.png|left|thumb|220px|[[Esophagogastroduodenoscopy|Endoscopic]] image of [[adenocarcinoma]] of duodenum seen in the post-bulbar duodenum.]]


In [[oncology]], '''small intestine cancer''', also '''small bowel cancer''' and '''cancer of the small bowel''', is a [[cancer]] of the [[small intestine]]. It is relatively rare compared to other gastrointestinal malignancies such as [[gastric cancer]] (stomach cancer) and [[colorectal cancer]].<ref name=terry>Terry SM, Santora T. Benign Neoplasm of the Small Intestine. eMedicine.com. URL: [http://www.emedicine.com/med/topic2652.htm http://www.emedicine.com/med/topic2652.htm]. Accessed on: June 2, 2006.</ref>
==[[Small intestine cancer overview|Overview]]==


Small intestine cancer can be subdivided into duodenal cancer (the first part of the small intestine) and cancer of the [[jejunum]] and [[ileum]] (the later two parts of the small intestine). 
==[[Small intestine cancer historical perspective|Historical Perspective]]==


Several different subtypes of small intestine cancer exist.  These include:
==[[Small intestine cancer classification|Classification]]==
*[[Adenocarcinoma]]
*[[Gastrointestinal stromal tumor]]
*[[Lymphoma]]
*[[Carcinoid]] ([[ileum]])


==Duodenal cancer==
==[[Small intestine cancer pathophysiology|Pathophysiology]]==
[[Image:Multiple Carcinoid Tumors of the Small Bowel 2.jpg|thumb|left|220px|Picture of a [[carcinoid tumour]] that encroaches into lumen of the [[small bowel]]. Pathology specimen. The prominent folds are [[plicae circulares]], a characteristic of [[small bowel]].]]
[[Image:Gray1098.png|left|thumb|200px|Image of Duodenal cancer locations.]]
Duodenal cancer is a [[cancer]] in the beginning section of the [[small intestine]]. It is relatively rare compared to [[gastric cancer]] and [[colorectal cancer]]. Its histology is usually [[adenocarcinoma]].  Familial adenomatous polyposis (FAP) is a risk factor for developing this cancer. 


The [[duodenum]] is the first part of the small intestine. It is located between the [[stomach]] and the [[jejunum]]. After foods combine with stomach acid, they descend into the duodenum where they mix with bile from the [[gall bladder]] and digestive juices from the [[pancreas]].
==[[Small intestine cancer causes|Causes]]==


Duodenal cancer is difficult to remove surgically because of the area that it resides in, there are many blood vessels supplying the lower body.  Chemotherapy is sometimes used to try and shrink the canceous mass.  Other times intestinal bypass surgery is tried to reroute the stomache to intestine connection around the blockage.
==[[Small intestine cancer differential diagnosis|Differentiating Small Intestine Cancer from other Diseases]]==
A 'Whipple' is a possible surgery that is tried sometimes with this cancer.


The cancerous mass tends to block food from getting to the small intestine. If food can not get to the intestines, it will cause pain, acid reflux, and weight loss because the food can not get to where it is supposed to be processed and absorbed by the body.
==[[Small intestine cancer epidemiology and demographics|Epidemiology and Demographics]]==


Some patients are fitted with tubes to either add nutrients (feeding tubes)  or drainage tubes to remove excess processed food that can not pass the blockage.
==[[Small intestine cancer risk factors|Risk Factors]]==


Patients with duodenal cancer may experience abdominal pain, weight loss, nausea, vomiting, and chronic GI bleeding.
==[[Small intestine cancer screening|Screening]]==


==Risk Factors==
==[[Small intestine cancer natural history, complications, and prognosis|Natural History, Complications, and Prognosis]]==
Risk factors for small intestine cancer include<ref>Delaunoit T, Neczyporenko F, Limburg PJ, Erlichman C. Pathogenesis and risk factors of small bowel adenocarcinoma: a colorectal cancer sibling? Am J Gastroenterol. 2005 Mar;100(3):703-10. PMID 15743371.</ref><ref>Chen AC, Neugut AI. Malignant Neoplasms of the Small Intestine. eMedicine.com. URL: [http://www.emedicine.com/MED/topic2651.htm http://www.emedicine.com/MED/topic2651.htm]. Accessed on: June 2, 2006.</ref>:
*[[Crohn's disease]]
*[[Celiac disease]]
*[[Radiation exposure]]
*Hereditary GI cancer syndromes: [[familial adenomatous polyposis]], [[hereditary nonpolyposis colorectal cancer]], [[Peutz-Jeghers syndrome]]
*[[Male]]


[[Benign tumour]]s and conditions that may be mistaken for cancer of the small bowel:
==Diagnosis==
*[[Hamartoma]]
[[Small intestine cancer diagnostic study of choice|Diagnostic study of choice]] | [[Small intestine cancer history and symptoms|History and Symptoms]] | [[Small intestine cancer physical examination|Physical Examination]] | [[Small intestine cancer laboratory findings|Laboratory Findings]] | [[Small intestine cancer electrocardiogram|Electrocardiogram]] | [[Small intestine cancer x ray|X-Ray Findings]] | [[Small intestine cancer echocardiography and ultrasound|Echocardiography and Ultrasound]] | [[Small intestine cancer CT|CT-Scan Findings]] | [[Small intestine cancer MRI|MRI Findings]] | [[Small intestine cancer other imaging findings|Other Imaging Findings]] | [[Small intestine cancer other diagnostic studies|Other Diagnostic Studies]]
*[[Tuberculosis]]


== References ==
==Treatment==
<references />
[[Small intestine cancer medical therapy|Medical Therapy]] | [[Small intestine cancer surgery|Surgery]] | [[Small intestine cancer primary prevention|Primary Prevention]] | [[Small intestine cancer secondary prevention|Secondary Prevention]] | [[Small intestine cancer cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Small intestine cancer future or investigational therapies|Future or Investigational Therapies]]


== External links ==
==Case Studies==
* [http://www.emedicine.com/med/topic2651.htm Malignancies of the Small Bowel] - emedicine.com.
[[Small intestine cancer case study one|Case #1]]
* [http://survivor-support.rare-cancer.org/forum/ Rare Cancer Support Group Forum] - survivor-support.rare-cancer.org.
* [http://health.groups.yahoo.com/group/duodenalcancer/ Yahoo Duodenal Cancer Support Group ]


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[[Category:Gastroenterology]]
[[Category:Types of cancer]]
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Latest revision as of 20:28, 26 March 2019

Small intestine cancer Microchapters

Home

Patient Information

Overview

Historical perspective

Classification

Pathophysiology

Causes

Differentiating Small intestine cancer from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural history, Complications, and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X-Ray

CT Scan

MRI

Echocardiography and Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Qurrat-ul-ain Abid, M.D.[2], Parminder Dhingra, M.D. [3]

Synonyms and keywords: Small bowel cancer


Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Small Intestine Cancer from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications, and Prognosis

Diagnosis

Diagnostic study of choice | History and Symptoms | Physical Examination | Laboratory Findings | Electrocardiogram | X-Ray Findings | Echocardiography and Ultrasound | CT-Scan Findings | MRI Findings | Other Imaging Findings | Other Diagnostic Studies

Treatment

Medical Therapy | Surgery | Primary Prevention | Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

Case Studies

Case #1