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==Overview== | |||
[[Secondary prevention]] for [[Hemophilia A|Hemophilia]] is aimed at preventing spontaneous or excessive bleeds in patients who are high risk, and relies on the use of recombinant clotting [[factor VIII]]/ IX to prevent bleeding episodes. | |||
==Secondary Prevention== | |||
Secondary preventive measures to avoid Hemophilia A and B include the following: | |||
*Patients should be counseled on safe practices and routine accident prevention. | |||
*Patients with moderate-to-severe hemophilia may be managed with prophylactic transfusions of recombinant clotting factor VIII/ IX in order to prevent bleeding episodes.<ref name="pmid22551339">{{cite journal| author=Franchini M, Mannucci PM| title=Past, present and future of hemophilia: a narrative review. | journal=Orphanet J Rare Dis | year= 2012 | volume= 7 | issue= | pages= 24 | pmid=22551339 | doi=10.1186/1750-1172-7-24 | pmc=3502605 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22551339 }} </ref> The goal of [[prophylaxis]] is usually to keep clotting factor levels at 1 percent or greater at all times.<ref>Prophylaxis: Administration and dosing schedules – World Federation of Hemophilia. Available at http://www.wfh.org/en/abd/prophylaxis/prophylaxis-administration-and-dosing-schedules. Accessed on Sept 20, 2016 </ref> | |||
*Routine prophylactic transfusions are not recommended for patients with mild hemophilia. | |||
==References== | ==References== | ||
{{reflist|2}} | |||
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{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} | ||
[[Category:Hematology]] | [[Category:Hematology]] | ||
[[Category:Pediatrics]] | [[Category:Pediatrics]] | ||
Latest revision as of 16:14, 16 July 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Fahd Yunus, M.D. [2]
Overview
Secondary prevention for Hemophilia is aimed at preventing spontaneous or excessive bleeds in patients who are high risk, and relies on the use of recombinant clotting factor VIII/ IX to prevent bleeding episodes.
Secondary Prevention
Secondary preventive measures to avoid Hemophilia A and B include the following:
- Patients should be counseled on safe practices and routine accident prevention.
- Patients with moderate-to-severe hemophilia may be managed with prophylactic transfusions of recombinant clotting factor VIII/ IX in order to prevent bleeding episodes.[1] The goal of prophylaxis is usually to keep clotting factor levels at 1 percent or greater at all times.[2]
- Routine prophylactic transfusions are not recommended for patients with mild hemophilia.
References
- ↑ Franchini M, Mannucci PM (2012). "Past, present and future of hemophilia: a narrative review". Orphanet J Rare Dis. 7: 24. doi:10.1186/1750-1172-7-24. PMC 3502605. PMID 22551339.
- ↑ Prophylaxis: Administration and dosing schedules – World Federation of Hemophilia. Available at http://www.wfh.org/en/abd/prophylaxis/prophylaxis-administration-and-dosing-schedules. Accessed on Sept 20, 2016