Acute megakaryoblastic leukemia laboratory findings: Difference between revisions
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{{Acute megakaryoblastic leukemia}} | {{Acute megakaryoblastic leukemia}} | ||
{{CMG}}; {{AE}} | |||
==Overview== | |||
==Laboratory Findings== | |||
The diagnosis of AMKL (M7) is based on the following: | |||
#[[Bone marrow]] [[biopsy]] demonstrating 30% or more leukemic cells of megakaryocytic lineage | |||
#Conducting tests that detect [[platelet-specific antibodies]] which could be [[monoclonal]] or [[polyclonal]]. | |||
#Bone marrow biopsy is recommended in patients who developed [[myelofibrosis]]. Visualization of blasts and mature megakaryocytes on biopsy sections is diagnostic. | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} |
Latest revision as of 14:23, 26 April 2021
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
Laboratory Findings
The diagnosis of AMKL (M7) is based on the following:
- Bone marrow biopsy demonstrating 30% or more leukemic cells of megakaryocytic lineage
- Conducting tests that detect platelet-specific antibodies which could be monoclonal or polyclonal.
- Bone marrow biopsy is recommended in patients who developed myelofibrosis. Visualization of blasts and mature megakaryocytes on biopsy sections is diagnostic.