ABCG1: Difference between revisions

Jump to navigation Jump to search
VisualWikitext
mNo edit summary
m (Bot: HTTP→HTTPS)
 
(5 intermediate revisions by one other user not shown)
Line 1: Line 1:
__NOTOC__<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->{{PBB_Controls
{{Infobox_gene}}
| update_page = yes
'''ATP-binding cassette sub-family G member 1''' is a [[protein]] that in humans is encoded by the ''ABCG1'' [[gene]].<ref name="pmid8659545">{{cite journal | vauthors = Chen H, Rossier C, Lalioti MD, Lynn A, Chakravarti A, Perrin G, Antonarakis SE | title = Cloning of the cDNA for a human homologue of the Drosophila white gene and mapping to chromosome 21q22.3 | journal = American Journal of Human Genetics | volume = 59 | issue = 1 | pages = 66–75 | date = Jul 1996 | pmid = 8659545 | pmc = 1915121 | doi =  }}</ref><ref name="pmid16870176">{{cite journal | vauthors = Engel T, Bode G, Lueken A, Knop M, Kannenberg F, Nofer JR, Assmann G, Seedorf U | title = Expression and functional characterization of ABCG1 splice variant ABCG1(666) | journal = FEBS Letters | volume = 580 | issue = 18 | pages = 4551–9 | date = Aug 2006 | pmid = 16870176 | pmc =  | doi = 10.1016/j.febslet.2006.07.006 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9619| accessdate = }}</ref> It is a homolog of the well-known ''[[Drosophila]]'' gene ''[[White (mutation)|white]]''.
| require_manual_inspection = no
 
| update_protein_box = yes
== Function ==
| update_summary = yes
 
| update_citations = yes
The protein encoded by this gene is a member of the superfamily of [[ATP-binding cassette transporter|ATP-binding cassette (ABC) transporter]]s. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. It is involved in macrophage, cholesterol and phospholipids transport, and may regulate cellular lipid homeostasis in other cell types. Several alternative splice variants have been identified.<ref name="entrez"/>
}}<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->{{GNF_Protein_box
 
| image = 
== See also ==
| image_source = 
| PDB =
| Name = ATP-binding cassette, sub-family G (WHITE), member 1
| HGNCid = 73
| Symbol = ABCG1
| AltSymbols =; ABC8; MGC34313; WHITE1
| OMIM = 603076
| ECnumber = 
| Homologene = 21022
| MGIid = 107704
| GeneAtlas_image1 = PBB_GE_ABCG1_204567_s_at_tn.png
| GeneAtlas_image2 = PBB_GE_ABCG1_211113_s_at_tn.png
| Function = {{GNF_GO|id=GO:0000166 |text = nucleotide binding}} {{GNF_GO|id=GO:0005524 |text = ATP binding}} {{GNF_GO|id=GO:0015196 |text = L-tryptophan transmembrane transporter activity}} {{GNF_GO|id=GO:0015216 |text = purine nucleotide transmembrane transporter activity}} {{GNF_GO|id=GO:0015646 |text = transmembrane transporter activity}} {{GNF_GO|id=GO:0016887 |text = ATPase activity}} {{GNF_GO|id=GO:0042626 |text = ATPase activity, coupled to transmembrane movement of substances}} {{GNF_GO|id=GO:0046983 |text = protein dimerization activity}}
| Component = {{GNF_GO|id=GO:0005624 |text = membrane fraction}} {{GNF_GO|id=GO:0005783 |text = endoplasmic reticulum}} {{GNF_GO|id=GO:0005887 |text = integral to plasma membrane}} {{GNF_GO|id=GO:0016020 |text = membrane}}
  | Process = {{GNF_GO|id=GO:0006869 |text = lipid transport}} {{GNF_GO|id=GO:0008203 |text = cholesterol metabolic process}} {{GNF_GO|id=GO:0009720 |text = detection of hormone stimulus}} {{GNF_GO|id=GO:0010033 |text = response to organic substance}} {{GNF_GO|id=GO:0042632 |text = cholesterol homeostasis}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 9619
    | Hs_Ensembl = ENSG00000160179
    | Hs_RefseqProtein = NP_004906
    | Hs_RefseqmRNA = NM_004915
    | Hs_GenLoc_db =   
    | Hs_GenLoc_chr = 21
    | Hs_GenLoc_start = 42509335
    | Hs_GenLoc_end = 42590421
    | Hs_Uniprot = P45844
    | Mm_EntrezGene = 11307
    | Mm_Ensembl = ENSMUSG00000024030
    | Mm_RefseqmRNA = NM_009593
    | Mm_RefseqProtein = NP_033723
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 17
    | Mm_GenLoc_start = 30784710
    | Mm_GenLoc_end = 30842784
    | Mm_Uniprot = Q0VDW9
  }}
}}
==Overview==
'''ATP-binding cassette, sub-family G (WHITE), member 1''', also known as '''ABCG1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9619| accessdate = }}</ref> The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. It is involved in macrophage cholesterol and phospholipids transport, and may regulate cellular lipid homeostasis in other cell types. Several alternative splice variants have been identified.
==See also==
* [[ATP-binding cassette transporter]]
* [[ATP-binding cassette transporter]]


==References==
== References ==
{{Reflist|2}}
{{reflist}}
{{Clear}}


==Further reading==
== Further reading ==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading
* {{cite journal | vauthors = Schmitz G, Langmann T, Heimerl S | title = Role of ABCG1 and other ABCG family members in lipid metabolism | journal = Journal of Lipid Research | volume = 42 | issue = 10 | pages = 1513–20 | date = Oct 2001 | pmid = 11590207 | doi =  }}
| citations =
* {{cite journal | vauthors = Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA | title = A "double adaptor" method for improved shotgun library construction | journal = Analytical Biochemistry | volume = 236 | issue = 1 | pages = 107–13 | date = Apr 1996 | pmid = 8619474 | doi = 10.1006/abio.1996.0138 }}
*{{cite journal | author=Schmitz G, Langmann T, Heimerl S |title=Role of ABCG1 and other ABCG family members in lipid metabolism. |journal=J. Lipid Res. |volume=42 |issue= 10 |pages= 1513-20 |year= 2002 |pmid= 11590207 |doi=  }}
* {{cite journal | vauthors = Savary S, Denizot F, Luciani M, Mattei M, Chimini G | title = Molecular cloning of a mammalian ABC transporter homologous to Drosophila white gene | journal = Mammalian Genome | volume = 7 | issue = 9 | pages = 673–6 | date = Sep 1996 | pmid = 8703120 | doi = 10.1007/s003359900203 }}
*{{cite journal | author=Andersson B, Wentland MA, Ricafrente JY, ''et al.'' |title=A "double adaptor" method for improved shotgun library construction. |journal=Anal. Biochem. |volume=236 |issue= 1 |pages= 107-13 |year= 1996 |pmid= 8619474 |doi= 10.1006/abio.1996.0138 }}
* {{cite journal | vauthors = Croop JM, Tiller GE, Fletcher JA, Lux ML, Raab E, Goldenson D, Son D, Arciniegas S, Wu RL | title = Isolation and characterization of a mammalian homolog of the Drosophila white gene | journal = Gene | volume = 185 | issue = 1 | pages = 77–85 | date = Jan 1997 | pmid = 9034316 | doi = 10.1016/S0378-1119(96)00633-6 }}
*{{cite journal | author=Chen H, Rossier C, Lalioti MD, ''et al.'' |title=Cloning of the cDNA for a human homologue of the Drosophila white gene and mapping to chromosome 21q22.3. |journal=Am. J. Hum. Genet. |volume=59 |issue= 1 |pages= 66-75 |year= 1996 |pmid= 8659545 |doi=  }}
* {{cite journal | vauthors = Yu W, Andersson B, Worley KC, Muzny DM, Ding Y, Liu W, Ricafrente JY, Wentland MA, Lennon G, Gibbs RA | title = Large-scale concatenation cDNA sequencing | journal = Genome Research | volume = 7 | issue = 4 | pages = 353–8 | date = Apr 1997 | pmid = 9110174 | pmc = 139146 | doi = 10.1101/gr.7.4.353 }}
*{{cite journal  | author=Savary S, Denizot F, Luciani M, ''et al.'' |title=Molecular cloning of a mammalian ABC transporter homologous to Drosophila white gene. |journal=Mamm. Genome |volume=7 |issue= 9 |pages= 673-6 |year= 1996 |pmid= 8703120 |doi= }}
* {{cite journal | vauthors = Klucken J, Büchler C, Orsó E, Kaminski WE, Porsch-Ozcürümez M, Liebisch G, Kapinsky M, Diederich W, Drobnik W, Dean M, Allikmets R, Schmitz G | title = ABCG1 (ABC8), the human homolog of the Drosophila white gene, is a regulator of macrophage cholesterol and phospholipid transport | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 97 | issue = 2 | pages = 817–22 | date = Jan 2000 | pmid = 10639163 | pmc = 15414 | doi = 10.1073/pnas.97.2.817 }}
*{{cite journal | author=Croop JM, Tiller GE, Fletcher JA, ''et al.'' |title=Isolation and characterization of a mammalian homolog of the Drosophila white gene. |journal=Gene |volume=185 |issue= 1 |pages= 77-85 |year= 1997 |pmid= 9034316 |doi= }}
* {{cite journal | vauthors = Venkateswaran A, Repa JJ, Lobaccaro JM, Bronson A, Mangelsdorf DJ, Edwards PA | title = Human white/murine ABC8 mRNA levels are highly induced in lipid-loaded macrophages. A transcriptional role for specific oxysterols | journal = The Journal of Biological Chemistry | volume = 275 | issue = 19 | pages = 14700–7 | date = May 2000 | pmid = 10799558 | doi = 10.1074/jbc.275.19.14700 }}
*{{cite journal | author=Yu W, Andersson B, Worley KC, ''et al.'' |title=Large-scale concatenation cDNA sequencing. |journal=Genome Res. |volume=7 |issue= 4 |pages= 353-8 |year= 1997 |pmid= 9110174 |doi= }}
* {{cite journal | vauthors = Berry A, Scott HS, Kudoh J, Talior I, Korostishevsky M, Wattenhofer M, Guipponi M, Barras C, Rossier C, Shibuya K, Wang J, Kawasaki K, Asakawa S, Minoshima S, Shimizu N, Antonarakis S, Bonné-Tamir B | title = Refined localization of autosomal recessive nonsyndromic deafness DFNB10 locus using 34 novel microsatellite markers, genomic structure, and exclusion of six known genes in the region | journal = Genomics | volume = 68 | issue = 1 | pages = 22–9 | date = Aug 2000 | pmid = 10950923 | doi = 10.1006/geno.2000.6253 }}
*{{cite journal | author=Klucken J, Büchler C, Orsó E, ''et al.'' |title=ABCG1 (ABC8), the human homolog of the Drosophila white gene, is a regulator of macrophage cholesterol and phospholipid transport. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=97 |issue= 2 |pages= 817-22 |year= 2000 |pmid= 10639163 |doi= }}
* {{cite journal | vauthors = Langmann T, Porsch-Ozcürümez M, Unkelbach U, Klucken J, Schmitz G | title = Genomic organization and characterization of the promoter of the human ATP-binding cassette transporter-G1 (ABCG1) gene | journal = Biochimica et Biophysica Acta | volume = 1494 | issue = 1-2 | pages = 175–80 | date = Nov 2000 | pmid = 11072082 | doi = 10.1016/s0167-4781(00)00215-3 }}
*{{cite journal | author=Venkateswaran A, Repa JJ, Lobaccaro JM, ''et al.'' |title=Human white/murine ABC8 mRNA levels are highly induced in lipid-loaded macrophages. A transcriptional role for specific oxysterols. |journal=J. Biol. Chem. |volume=275 |issue= 19 |pages= 14700-7 |year= 2000 |pmid= 10799558 |doi= }}
* {{cite journal | vauthors = Lorkowski S, Rust S, Engel T, Jung E, Tegelkamp K, Galinski EA, Assmann G, Cullen P | title = Genomic sequence and structure of the human ABCG1 (ABC8) gene | journal = Biochemical and Biophysical Research Communications | volume = 280 | issue = 1 | pages = 121–31 | date = Jan 2001 | pmid = 11162488 | doi = 10.1006/bbrc.2000.4089 }}
*{{cite journal  | author=Hattori M, Fujiyama A, Taylor TD, ''et al.'' |title=The DNA sequence of human chromosome 21. |journal=Nature |volume=405 |issue= 6784 |pages= 311-9 |year= 2000 |pmid= 10830953 |doi= 10.1038/35012518 }}
* {{cite journal | vauthors = Porsch-Ozcurumez M, Langmann T, Heimerl S, Borsukova H, Kaminski WE, Drobnik W, Honer C, Schumacher C, Schmitz G | title = The zinc finger protein 202 (ZNF202) is a transcriptional repressor of ATP binding cassette transporter A1 (ABCA1) and ABCG1 gene expression and a modulator of cellular lipid efflux | journal = The Journal of Biological Chemistry | volume = 276 | issue = 15 | pages = 12427–33 | date = Apr 2001 | pmid = 11279031 | doi = 10.1074/jbc.M100218200 }}
*{{cite journal | author=Berry A, Scott HS, Kudoh J, ''et al.'' |title=Refined localization of autosomal recessive nonsyndromic deafness DFNB10 locus using 34 novel microsatellite markers, genomic structure, and exclusion of six known genes in the region. |journal=Genomics |volume=68 |issue= 1 |pages= 22-9 |year= 2001 |pmid= 10950923 |doi= 10.1006/geno.2000.6253 }}
* {{cite journal | vauthors = Lorkowski S, Kratz M, Wenner C, Schmidt R, Weitkamp B, Fobker M, Reinhardt J, Rauterberg J, Galinski EA, Cullen P | title = Expression of the ATP-binding cassette transporter gene ABCG1 (ABC8) in Tangier disease | journal = Biochemical and Biophysical Research Communications | volume = 283 | issue = 4 | pages = 821–30 | date = May 2001 | pmid = 11350058 | doi = 10.1006/bbrc.2001.4863 }}
*{{cite journal | author=Langmann T, Porsch-Ozcürümez M, Unkelbach U, ''et al.'' |title=Genomic organization and characterization of the promoter of the human ATP-binding cassette transporter-G1 (ABCG1) gene. |journal=Biochim. Biophys. Acta |volume=1494 |issue= 1-2 |pages= 175-80 |year= 2000 |pmid= 11072082 |doi= }}
* {{cite journal | vauthors = Kennedy MA, Venkateswaran A, Tarr PT, Xenarios I, Kudoh J, Shimizu N, Edwards PA | title = Characterization of the human ABCG1 gene: liver X receptor activates an internal promoter that produces a novel transcript encoding an alternative form of the protein | journal = The Journal of Biological Chemistry | volume = 276 | issue = 42 | pages = 39438–47 | date = Oct 2001 | pmid = 11500512 | doi = 10.1074/jbc.M105863200 }}
*{{cite journal | author=Lorkowski S, Rust S, Engel T, ''et al.'' |title=Genomic sequence and structure of the human ABCG1 (ABC8) gene. |journal=Biochem. Biophys. Res. Commun. |volume=280 |issue= 1 |pages= 121-31 |year= 2001 |pmid= 11162488 |doi= 10.1006/bbrc.2000.4089 }}
* {{cite journal | vauthors = Kaplan R, Gan X, Menke JG, Wright SD, Cai TQ | title = Bacterial lipopolysaccharide induces expression of ABCA1 but not ABCG1 via an LXR-independent pathway | journal = Journal of Lipid Research | volume = 43 | issue = 6 | pages = 952–9 | date = Jun 2002 | pmid = 12032171 | doi =  }}
*{{cite journal | author=Porsch-Ozcurumez M, Langmann T, Heimerl S, ''et al.'' |title=The zinc finger protein 202 (ZNF202) is a transcriptional repressor of ATP binding cassette transporter A1 (ABCA1) and ABCG1 gene expression and a modulator of cellular lipid efflux. |journal=J. Biol. Chem. |volume=276 |issue= 15 |pages= 12427-33 |year= 2001 |pmid= 11279031 |doi= 10.1074/jbc.M100218200 }}
* {{cite journal | vauthors = Cserepes J, Szentpétery Z, Seres L, Ozvegy-Laczka C, Langmann T, Schmitz G, Glavinas H, Klein I, Homolya L, Váradi A, Sarkadi B, Elkind NB | title = Functional expression and characterization of the human ABCG1 and ABCG4 proteins: indications for heterodimerization | journal = Biochemical and Biophysical Research Communications | volume = 320 | issue = 3 | pages = 860–7 | date = Jul 2004 | pmid = 15240127 | doi = 10.1016/j.bbrc.2004.06.037 }}
*{{cite journal | author=Lorkowski S, Kratz M, Wenner C, ''et al.'' |title=Expression of the ATP-binding cassette transporter gene ABCG1 (ABC8) in Tangier disease. |journal=Biochem. Biophys. Res. Commun. |volume=283 |issue= 4 |pages= 821-30 |year= 2001 |pmid= 11350058 |doi= 10.1006/bbrc.2001.4863 }}
*{{cite journal | author=Kennedy MA, Venkateswaran A, Tarr PT, ''et al.'' |title=Characterization of the human ABCG1 gene: liver X receptor activates an internal promoter that produces a novel transcript encoding an alternative form of the protein. |journal=J. Biol. Chem. |volume=276 |issue= 42 |pages= 39438-47 |year= 2001 |pmid= 11500512 |doi= 10.1074/jbc.M105863200 }}
*{{cite journal | author=Kaplan R, Gan X, Menke JG, ''et al.'' |title=Bacterial lipopolysaccharide induces expression of ABCA1 but not ABCG1 via an LXR-independent pathway. |journal=J. Lipid Res. |volume=43 |issue= 6 |pages= 952-9 |year= 2003 |pmid= 12032171 |doi=  }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal  | author=Cserepes J, Szentpétery Z, Seres L, ''et al.'' |title=Functional expression and characterization of the human ABCG1 and ABCG4 proteins: indications for heterodimerization. |journal=Biochem. Biophys. Res. Commun. |volume=320 |issue= 3 |pages= 860-7 |year= 2004 |pmid= 15240127 |doi= 10.1016/j.bbrc.2004.06.037 }}
}}
{{refend}}
{{refend}}


== External links ==
== External links ==
* {{MeshName|ABCG1+protein,+human}}
* {{MeshName|ABCG1+protein,+human}}
* {{UCSC gene info|ABCG1}}


{{membrane-protein-stub}}
{{NLM content}}
{{NLM content}}
{{Membrane transport proteins}}
{{ABC transporters}}
 
{{DEFAULTSORT:Abcg1}}
[[Category:ABC transporters]]
[[Category:ABC transporters]]
{{WikiDoc Sources}}
 
 
{{membrane-protein-stub}}

Latest revision as of 17:40, 29 August 2017

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

n/a

n/a

Ensembl

n/a

n/a

UniProt

n/a

n/a

RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

ATP-binding cassette sub-family G member 1 is a protein that in humans is encoded by the ABCG1 gene.[1][2][3] It is a homolog of the well-known Drosophila gene white.

Function

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. It is involved in macrophage, cholesterol and phospholipids transport, and may regulate cellular lipid homeostasis in other cell types. Several alternative splice variants have been identified.[3]

See also

References

  1. ↑ Chen H, Rossier C, Lalioti MD, Lynn A, Chakravarti A, Perrin G, Antonarakis SE (Jul 1996). "Cloning of the cDNA for a human homologue of the Drosophila white gene and mapping to chromosome 21q22.3". American Journal of Human Genetics. 59 (1): 66–75. PMC 1915121. PMID 8659545.
  2. ↑ Engel T, Bode G, Lueken A, Knop M, Kannenberg F, Nofer JR, Assmann G, Seedorf U (Aug 2006). "Expression and functional characterization of ABCG1 splice variant ABCG1(666)". FEBS Letters. 580 (18): 4551–9. doi:10.1016/j.febslet.2006.07.006. PMID 16870176.
  3. ↑ 3.0 3.1 "Entrez Gene: ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1".

Further reading

  • Schmitz G, Langmann T, Heimerl S (Oct 2001). "Role of ABCG1 and other ABCG family members in lipid metabolism". Journal of Lipid Research. 42 (10): 1513–20. PMID 11590207.
  • Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA (Apr 1996). "A "double adaptor" method for improved shotgun library construction". Analytical Biochemistry. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
  • Savary S, Denizot F, Luciani M, Mattei M, Chimini G (Sep 1996). "Molecular cloning of a mammalian ABC transporter homologous to Drosophila white gene". Mammalian Genome. 7 (9): 673–6. doi:10.1007/s003359900203. PMID 8703120.
  • Croop JM, Tiller GE, Fletcher JA, Lux ML, Raab E, Goldenson D, Son D, Arciniegas S, Wu RL (Jan 1997). "Isolation and characterization of a mammalian homolog of the Drosophila white gene". Gene. 185 (1): 77–85. doi:10.1016/S0378-1119(96)00633-6. PMID 9034316.
  • Yu W, Andersson B, Worley KC, Muzny DM, Ding Y, Liu W, Ricafrente JY, Wentland MA, Lennon G, Gibbs RA (Apr 1997). "Large-scale concatenation cDNA sequencing". Genome Research. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
  • Klucken J, Büchler C, Orsó E, Kaminski WE, Porsch-Ozcürümez M, Liebisch G, Kapinsky M, Diederich W, Drobnik W, Dean M, Allikmets R, Schmitz G (Jan 2000). "ABCG1 (ABC8), the human homolog of the Drosophila white gene, is a regulator of macrophage cholesterol and phospholipid transport". Proceedings of the National Academy of Sciences of the United States of America. 97 (2): 817–22. doi:10.1073/pnas.97.2.817. PMC 15414. PMID 10639163.
  • Venkateswaran A, Repa JJ, Lobaccaro JM, Bronson A, Mangelsdorf DJ, Edwards PA (May 2000). "Human white/murine ABC8 mRNA levels are highly induced in lipid-loaded macrophages. A transcriptional role for specific oxysterols". The Journal of Biological Chemistry. 275 (19): 14700–7. doi:10.1074/jbc.275.19.14700. PMID 10799558.
  • Berry A, Scott HS, Kudoh J, Talior I, Korostishevsky M, Wattenhofer M, Guipponi M, Barras C, Rossier C, Shibuya K, Wang J, Kawasaki K, Asakawa S, Minoshima S, Shimizu N, Antonarakis S, Bonné-Tamir B (Aug 2000). "Refined localization of autosomal recessive nonsyndromic deafness DFNB10 locus using 34 novel microsatellite markers, genomic structure, and exclusion of six known genes in the region". Genomics. 68 (1): 22–9. doi:10.1006/geno.2000.6253. PMID 10950923.
  • Langmann T, Porsch-Ozcürümez M, Unkelbach U, Klucken J, Schmitz G (Nov 2000). "Genomic organization and characterization of the promoter of the human ATP-binding cassette transporter-G1 (ABCG1) gene". Biochimica et Biophysica Acta. 1494 (1–2): 175–80. doi:10.1016/s0167-4781(00)00215-3. PMID 11072082.
  • Lorkowski S, Rust S, Engel T, Jung E, Tegelkamp K, Galinski EA, Assmann G, Cullen P (Jan 2001). "Genomic sequence and structure of the human ABCG1 (ABC8) gene". Biochemical and Biophysical Research Communications. 280 (1): 121–31. doi:10.1006/bbrc.2000.4089. PMID 11162488.
  • Porsch-Ozcurumez M, Langmann T, Heimerl S, Borsukova H, Kaminski WE, Drobnik W, Honer C, Schumacher C, Schmitz G (Apr 2001). "The zinc finger protein 202 (ZNF202) is a transcriptional repressor of ATP binding cassette transporter A1 (ABCA1) and ABCG1 gene expression and a modulator of cellular lipid efflux". The Journal of Biological Chemistry. 276 (15): 12427–33. doi:10.1074/jbc.M100218200. PMID 11279031.
  • Lorkowski S, Kratz M, Wenner C, Schmidt R, Weitkamp B, Fobker M, Reinhardt J, Rauterberg J, Galinski EA, Cullen P (May 2001). "Expression of the ATP-binding cassette transporter gene ABCG1 (ABC8) in Tangier disease". Biochemical and Biophysical Research Communications. 283 (4): 821–30. doi:10.1006/bbrc.2001.4863. PMID 11350058.
  • Kennedy MA, Venkateswaran A, Tarr PT, Xenarios I, Kudoh J, Shimizu N, Edwards PA (Oct 2001). "Characterization of the human ABCG1 gene: liver X receptor activates an internal promoter that produces a novel transcript encoding an alternative form of the protein". The Journal of Biological Chemistry. 276 (42): 39438–47. doi:10.1074/jbc.M105863200. PMID 11500512.
  • Kaplan R, Gan X, Menke JG, Wright SD, Cai TQ (Jun 2002). "Bacterial lipopolysaccharide induces expression of ABCA1 but not ABCG1 via an LXR-independent pathway". Journal of Lipid Research. 43 (6): 952–9. PMID 12032171.
  • Cserepes J, Szentpétery Z, Seres L, Ozvegy-Laczka C, Langmann T, Schmitz G, Glavinas H, Klein I, Homolya L, Váradi A, Sarkadi B, Elkind NB (Jul 2004). "Functional expression and characterization of the human ABCG1 and ABCG4 proteins: indications for heterodimerization". Biochemical and Biophysical Research Communications. 320 (3): 860–7. doi:10.1016/j.bbrc.2004.06.037. PMID 15240127.

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


Retrieved from "https://www.wikidoc.org/index.php?title=ABCG1&oldid=1419907"