Liposarcoma CT: Difference between revisions

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* The appearance and morphologic relationship between these areas frequently allow identification of the specific histologic subtype of liposarcoma.
* The appearance and morphologic relationship between these areas frequently allow identification of the specific histologic subtype of liposarcoma.


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{| style="border: 0px; font-size: 90%; margin: 3px; width: 900px;" align=center
|valign=top|
|valign=top|
|+
|+
| style="padding: 5px 5px; background: #4479BA; font-weight: bold; width: 200px; text-align:center" | {{fontcolor|#FFF|Subtypes}}
| style="padding: 5px 5px; background: #4479BA; font-weight: bold; width: 300px; text-align:center" | {{fontcolor|#FFF|Subtypes}}
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| style="padding: 5px 5px; background: #4479BA; font-weight: bold; width: 100px; text-align:center" | {{fontcolor|#FFF|Density}}
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|-
|-
| style="background: #4479BA; font-weight: bold;" | {{fontcolor|#FFF|Atypical lipomatous tumor/well-differentiated liposarcoma (ALT/WDL)}}
| style="background: #4479BA; font-weight: bold;" | {{fontcolor|#FFF|Atypical lipomatous tumor/well-differentiated liposarcoma (ALT/WDL)}}
| style="padding: 5px 5px; background: #DCDCDC;" |  
| style="padding: 5px 5px; background: #DCDCDC;" | Fat
| style="padding: 5px 5px; background: #F5F5F5;" |  
| style="padding: 5px 5px; background: #F5F5F5;" | Smooth regular
| style="padding: 5px 5px; background: #DCDCDC;" |  
| style="padding: 5px 5px; background: #DCDCDC;" | > 65%
| style="padding: 5px 5px; background: #F5F5F5;" |  
| style="padding: 5px 5px; background: #F5F5F5;" | ++
| style="padding: 5px 5px; background: #DCDCDC;" |  
| style="padding: 5px 5px; background: #DCDCDC;" | Few/none
|-
|-
| style="background: #4479BA; font-weight: bold" | {{fontcolor|#FFF|Dedifferentiated liposarcoma (DDL)}}
| style="background: #4479BA; font-weight: bold" | {{fontcolor|#FFF|Dedifferentiated liposarcoma (DDL)}}
| style="padding: 5px 5px; background: #DCDCDC;" |  
| style="padding: 5px 5px; background: #DCDCDC;" | Mixed
| style="padding: 5px 5px; background: #F5F5F5;" |
| style="padding: 5px 5px; background: #F5F5F5;" | Rough irregular
| style="padding: 5px 5px; background: #DCDCDC;" |  
| style="padding: 5px 5px; background: #DCDCDC;" | 30-60%
| style="padding: 5px 5px; background: #F5F5F5;" |  
| style="padding: 5px 5px; background: #F5F5F5;" | +++
| style="padding: 5px 5px; background: #DCDCDC;" |  
| style="padding: 5px 5px; background: #DCDCDC;" | Few/none
|-
|-
| style="background: #4479BA; font-weight: bold; width: 100px;" | {{fontcolor|#FFF|Myxoid/round cell liposarcoma (ML/RCL)}}
| style="background: #4479BA; font-weight: bold; width: 100px;" | {{fontcolor|#FFF|Myxoid/round cell liposarcoma (ML/RCL)}}
| style="padding: 5px 5px; background: #DCDCDC;" |  
| style="padding: 5px 5px; background: #DCDCDC;" | Mixed
| style="padding: 5px 5px; background: #F5F5F5;" |  
| style="padding: 5px 5px; background: #F5F5F5;" | Rough irregular
| style="padding: 5px 5px; background: #DCDCDC;" |  
| style="padding: 5px 5px; background: #DCDCDC;" | 25-50%
| style="padding: 5px 5px; background: #F5F5F5;" |  
| style="padding: 5px 5px; background: #F5F5F5;" | +
| style="padding: 5px 5px; background: #DCDCDC;" |  
| style="padding: 5px 5px; background: #DCDCDC;" |  
|-
|-
| style="background: #4479BA; font-weight: bold" | {{fontcolor|#FFF|Pleomorphic liposarcoma (PL)}}
| style="background: #4479BA; font-weight: bold" | {{fontcolor|#FFF|Pleomorphic liposarcoma (PL)}}
| style="padding: 5px 5px; background: #DCDCDC;" |  
| style="padding: 5px 5px; background: #DCDCDC;" | Soft tissue
| style="padding: 5px 5px; background: #F5F5F5;" |
| style="padding: 5px 5px; background: #F5F5F5;" | Incomplete irregular
| style="padding: 5px 5px; background: #DCDCDC;" |  
| style="padding: 5px 5px; background: #DCDCDC;" | 6-25%
| style="padding: 5px 5px; background: #F5F5F5;" |  
| style="padding: 5px 5px; background: #F5F5F5;" | +
| style="padding: 5px 5px; background: #DCDCDC;" |  
| style="padding: 5px 5px; background: #DCDCDC;" | Few/none
|-
|-
| style="background: #4479BA; font-weight: bold" | {{fontcolor|#FFF|Mixed-type liposarcoma}}
| style="background: #4479BA; font-weight: bold" | {{fontcolor|#FFF|Mixed-type liposarcoma}}
| style="padding: 5px 5px; background: #DCDCDC;" |  
| style="padding: 5px 5px; background: #DCDCDC;" | Mixed
| style="padding: 5px 5px; background: #F5F5F5;" |
| style="padding: 5px 5px; background: #F5F5F5;" |Smooth regular
| style="padding: 5px 5px; background: #DCDCDC;" |  
| style="padding: 5px 5px; background: #DCDCDC;" | 30-60%
| style="padding: 5px 5px; background: #F5F5F5;" |  
| style="padding: 5px 5px; background: #F5F5F5;" | ++
| style="padding: 5px 5px; background: #DCDCDC;" |
| style="padding: 5px 5px; background: #DCDCDC;" |
|-  
|-  
| style="padding: 5px 5px; background: #F5F5F5;" colspan=6|<small> Table adapted from </small>
| style="padding: 5px 5px; background: #F5F5F5;" colspan=6|<small> Table adapted from CT Manifestations in Histologic Subtypes of Retroperitoneal Liposarcoma<ref>{{Cite journal
| author = [[Jing Lu]], [[Qin Qin]], [[Liang-Liang Zhan]], [[Xi Yang]], [[Qing Xu]], [[Jing Yu]], [[Li-Na Dou]], [[Hao Zhang]], [[Yan Yang]], [[Xiao-Chen Chen]], [[Yue-Hua Yang]], [[Hong-Yan Cheng]] & [[Xin-Chen Sun]]
| title = Computed tomography manifestations of histologic subtypes of retroperitoneal liposarcoma
| journal = [[Asian Pacific journal of cancer prevention : APJCP]]
| volume = 15
| issue = 15
| pages = 6041–6046
| year = 2014
| month =
| pmid = 25124571
}}</ref> </small>
|}
|}


Revision as of 18:30, 19 September 2014

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

CT Scan

  • Imaging findings of liposarcoma are frequently characteristic.
  • Focal or diffuse areas of fat associated with nonlipomatous components are commonly detected on computed tomographic or magnetic resonance images.
  • The appearance and morphologic relationship between these areas frequently allow identification of the specific histologic subtype of liposarcoma.
Subtypes Density Margins Fat Content Lymph Nodes Around the Tumor Calcifications
Atypical lipomatous tumor/well-differentiated liposarcoma (ALT/WDL) Fat Smooth regular > 65% ++ Few/none
Dedifferentiated liposarcoma (DDL) Mixed Rough irregular 30-60% +++ Few/none
Myxoid/round cell liposarcoma (ML/RCL) Mixed Rough irregular 25-50% +
Pleomorphic liposarcoma (PL) Soft tissue Incomplete irregular 6-25% + Few/none
Mixed-type liposarcoma Mixed Smooth regular 30-60% ++
Table adapted from CT Manifestations in Histologic Subtypes of Retroperitoneal Liposarcoma[1]



References

  1. ↑ Jing Lu, Qin Qin, Liang-Liang Zhan, Xi Yang, Qing Xu, Jing Yu, Li-Na Dou, Hao Zhang, Yan Yang, Xiao-Chen Chen, Yue-Hua Yang, Hong-Yan Cheng & Xin-Chen Sun (2014). "Computed tomography manifestations of histologic subtypes of retroperitoneal liposarcoma". Asian Pacific journal of cancer prevention : APJCP. 15 (15): 6041–6046. PMID 25124571.


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