Liposarcoma natural history: Difference between revisions
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==Natural History== | ==Natural History== | ||
*The natural history of liposarcoma would depend on the histopathological subtype and location. | |||
*Liposarcomas may remain asymptomatic for a long time, specially if they are located in the retroperitoneum. | *Liposarcomas may remain asymptomatic for a long time, specially if they are located in the retroperitoneum. | ||
*The common presentation for a liposarcoma located in the soft tissue of the skin is a painless growing mass without other symptoms. | *The common presentation for a liposarcoma located in the soft tissue of the skin is a painless growing mass without other symptoms. | ||
*Retroperitoneal liposarcomas may present as a dull abdominal pain, weight loss and increase abdominal girth. | *The lower extremities are the most common location of liposarcomas. <ref name="PetersonKransdorf2003">{{cite journal|last1=Peterson|first1=Jeffrey J.|last2=Kransdorf|first2=Mark J.|last3=Bancroft|first3=Laura W.|last4=O'Connor|first4=Mary I.|title=Malignant fatty tumors: classification, clinical course, imaging appearance and treatment|journal=Skeletal Radiology|volume=32|issue=9|year=2003|pages=493–503|issn=0364-2348|doi=10.1007/s00256-003-0647-8}}</ref> | ||
*Between 10 and 15% of patients may present with pain in the affected region. <ref name="PetersonKransdorf2003">{{cite journal|last1=Peterson|first1=Jeffrey J.|last2=Kransdorf|first2=Mark J.|last3=Bancroft|first3=Laura W.|last4=O'Connor|first4=Mary I.|title=Malignant fatty tumors: classification, clinical course, imaging appearance and treatment|journal=Skeletal Radiology|volume=32|issue=9|year=2003|pages=493–503|issn=0364-2348|doi=10.1007/s00256-003-0647-8}}</ref> | |||
*Retroperitoneal liposarcomas may present as a dull abdominal pain, weight loss and increase abdominal girth. | |||
==Complications== | ==Complications== |
Revision as of 14:07, 22 September 2014
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Alejandro Lemor, M.D. [2]
Overview
Natural History
- The natural history of liposarcoma would depend on the histopathological subtype and location.
- Liposarcomas may remain asymptomatic for a long time, specially if they are located in the retroperitoneum.
- The common presentation for a liposarcoma located in the soft tissue of the skin is a painless growing mass without other symptoms.
- The lower extremities are the most common location of liposarcomas. [1]
- Between 10 and 15% of patients may present with pain in the affected region. [1]
- Retroperitoneal liposarcomas may present as a dull abdominal pain, weight loss and increase abdominal girth.
Complications
Metastatic Disease
Prognosis
The prognosis of liposarcoma will depend on the histopathological subtype. Atypical lipomatous neoplasm/well-differentiated liposarcoma has a low metastasis risk, but may recur locally. The pleomorphic liposarcoma has a high metastasis potential and a high recurrence.
References