Liposarcoma CT: Difference between revisions
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==Overview== | ==Overview== | ||
CT imaging is one of the most important tests for the diagnosis of liposarcoma. CT should assess the size, location and depth of the liposarcoma, as well as the lymph node involvement and distant metastasis. CT findings can be correlated with the histopathological subtype. | CT imaging is one of the most important tests for the diagnosis of liposarcoma. CT should assess the size, location and depth of the liposarcoma, as well as the [[lymph node]] involvement and distant [[metastasis]]. CT findings can be correlated with the [[histopathological]] subtype. | ||
==CT Scan== | ==CT Scan== | ||
Revision as of 15:49, 22 September 2014
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Liposarcoma Microchapters |
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Treatment |
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Case Studies |
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Liposarcoma CT On the Web |
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American Roentgen Ray Society Images of Liposarcoma CT |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Alejandro Lemor, M.D. [2]
Overview
CT imaging is one of the most important tests for the diagnosis of liposarcoma. CT should assess the size, location and depth of the liposarcoma, as well as the lymph node involvement and distant metastasis. CT findings can be correlated with the histopathological subtype.
CT Scan
- The appearance and morphologic relationship in the CT imaging of lipid and non-lipid components frequently allows the identification of the specific histologic subtype of liposarcoma.[1]
- A CT image commonly detects focal or diffuse areas of lipid and non-lipid components.
- CT scan is also used to determine the stage of the disease assessing the presence of lymph nodes and distant metastasis.[2]
CT Findings According to the Liposarcoma Subtype
| Subtypes | Density | Margins | Fat Content | Nodular muscle-density area in tumor | Calcifications | Necrotic or cystic areas |
| Atypical lipomatous tumor/well-differentiated liposarcoma (ALT/WDL) | Fat | Smooth regular | > 65% | ++ | Few/none | + |
| Dedifferentiated liposarcoma (DDL) | Mixed | Rough irregular | 30-60% | +++ | Few/none | ++ |
| Myxoid/round cell liposarcoma (ML/RCL) | Mixed | Rough irregular | 25-50% | + | Common | +++ |
| Pleomorphic liposarcoma (PL) | Soft tissue | Incomplete irregular | 6-25% | + | Few/none | + |
| Mixed-type liposarcoma | Mixed | Smooth regular | 30-60% | ++ | Common | + |
| Table adapted from CT Manifestations in Histologic Subtypes of Retroperitoneal Liposarcoma[3] | ||||||
CT Gallery
References
- ↑ Kim, T; Murakami, T; Oi, H; Tsuda, K; Matsushita, M; Tomoda, K; Fukuda, H; Nakamura, H (1996). "CT and MR imaging of abdominal liposarcoma". American Journal of Roentgenology. 166 (4): 829–833. doi:10.2214/ajr.166.4.8610559. ISSN 0361-803X.
- ↑ Kumarasamy, Narmadan A.; Gayer, Gabriela (2011). "Retroperitoneal Sarcomas". Seminars in Ultrasound, CT and MRI. 32 (5): 422–432. doi:10.1053/j.sult.2011.06.002. ISSN 0887-2171.
- ↑ Jing Lu, Qin Qin, Liang-Liang Zhan, Xi Yang, Qing Xu, Jing Yu, Li-Na Dou, Hao Zhang, Yan Yang, Xiao-Chen Chen, Yue-Hua Yang, Hong-Yan Cheng & Xin-Chen Sun (2014). "Computed tomography manifestations of histologic subtypes of retroperitoneal liposarcoma". Asian Pacific journal of cancer prevention : APJCP. 15 (15): 6041–6046. PMID 25124571.