Liposarcoma risk factors: Difference between revisions
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Revision as of 15:53, 24 August 2015
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Liposarcoma Microchapters |
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Liposarcoma risk factors On the Web |
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Risk calculators and risk factors for Liposarcoma risk factors |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]
Overview
Risk factors of liposarcoma includes chemical carcinogen, genetic disorders, radiation and immunodeficiency. These increases the risk of liposarcoma in general population.
Risk factors
Liposarcoma is associated with a number of risk factors. Few of them are listed below.
Chemical carcinogens
- Phenoxyacetic herbicides
- Chlorophenols
- Dioxin contaminations
Radiation
Post irradiation sarcoma has an incidence of 1%. Risk has been found with adjuvant therapy of radiation for breast carcinoma. Risk increases with dose and a dose of 50 GY or more of radiation has been recorded with increased risk of sarcoma. The mean period between exposure to radiation and tumor diagnosis is 10 years.
Immunodeficiency
Regional acquired immunodeficiency is sometimes associated with liposarcoma
Genetic susceptibility
Li-Fraumeni syndrome is associated with liposarcoma