Aplastic anemia medical therapy: Difference between revisions
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* [[Blood transfusion]]s can help keep blood cell counts at acceptable levels. | * [[Blood transfusion]]s can help keep blood cell counts at acceptable levels. | ||
* Blood transfusions help relieve the symptoms of aplastic anemia, but they're not a permanent treatment. | * Blood transfusions help relieve the symptoms of aplastic anemia, but they're not a permanent treatment. | ||
* Blood and marrow stem cell transplants may cure aplastic anemia in people who can have this type of treatment. | * Blood and marrow stem cell transplants may cure aplastic anemia in people who can have this type of treatment. | ||
* The transplant works best in children and young adults with severe aplastic anemia who are in good health and who have matched donors. | * The transplant works best in children and young adults with severe aplastic anemia who are in good health and who have matched donors. | ||
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* Medications are used to: | * Medications are used to: | ||
::1. '''Stimulate bone marrow''' (erythropoietin and colony-stimulating factors). These medicines have some risks. However, if this treatment works well, it can help avoid the need for blood transfusions. | ::1. '''Stimulate bone marrow''' (erythropoietin and colony-stimulating factors). These medicines have some risks. However, if this treatment works well, it can help avoid the need for blood transfusions. | ||
::2. '''Suppress immune system''' | ::2. '''Suppress immune system''' | ||
::* Medicines that suppress the immune system don't cure aplastic anemia. | |||
::* However, they can relieve its symptoms and reduce complications. | |||
::* These medicines often are used for people who can't have blood and marrow stem cell transplants or who are waiting for transplants. | |||
::* Medications commonly used are: antithymocyte globulin (ATG), cyclosporine, and methylprednisolone. | |||
::* Medicines that suppress the immune system can have side effects. They also may increase the risk of developing leukemia or myelodysplasia | |||
:: | |||
::3. '''Prevent and treat infections''' - antibiotic and antiviral medicines to prevent and treat infections. | ::3. '''Prevent and treat infections''' - antibiotic and antiviral medicines to prevent and treat infections. | ||
* It may take a few months to notice the effects of these medicines. Most often, as blood cell counts rise, symptoms lessen. | * It may take a few months to notice the effects of these medicines. Most often, as blood cell counts rise, symptoms lessen. |
Revision as of 18:55, 21 August 2018
Aplastic anemia Microchapters |
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Treatment |
Case Studies |
Aplastic anemia medical therapy On the Web |
American Roentgen Ray Society Images of Aplastic anemia medical therapy |
Risk calculators and risk factors for Aplastic anemia medical therapy |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Priyamvada Singh, M.D. [2]
Overview
Treatments for aplastic anemia include blood transfusions, blood and marrow stem cell transplants, and medicines.
Medical Therapy
- Treatments for aplastic anemia include blood transfusions, blood and marrow stem cell transplants, and medicines.
- These treatments can prevent or limit complications, relieve symptoms, and improve quality of life.
- Blood and marrow stem cell transplants may cure the disorder in some people who are eligible for a transplant.
- Removing a known cause of aplastic anemia, such as exposure to a toxin, also may cure the condition.
- People who have mild or moderate aplastic anemia may not need treatment as long as the condition doesn't get worse.
- People who have severe aplastic anemia need medical treatment right away to prevent complications.
- People who have very severe aplastic anemia need emergency medical care in a hospital. Very severe aplastic anemia can be fatal if it's not treated right away.
- Blood transfusions can help keep blood cell counts at acceptable levels.
- Blood transfusions help relieve the symptoms of aplastic anemia, but they're not a permanent treatment.
- Blood and marrow stem cell transplants may cure aplastic anemia in people who can have this type of treatment.
- The transplant works best in children and young adults with severe aplastic anemia who are in good health and who have matched donors.
- Older people may be less able to handle the treatments needed to prepare the body for the transplant. They're also more likely to have complications after the transplant.
- Medications are used to:
- 1. Stimulate bone marrow (erythropoietin and colony-stimulating factors). These medicines have some risks. However, if this treatment works well, it can help avoid the need for blood transfusions.
- 2. Suppress immune system
- Medicines that suppress the immune system don't cure aplastic anemia.
- However, they can relieve its symptoms and reduce complications.
- These medicines often are used for people who can't have blood and marrow stem cell transplants or who are waiting for transplants.
- Medications commonly used are: antithymocyte globulin (ATG), cyclosporine, and methylprednisolone.
- Medicines that suppress the immune system can have side effects. They also may increase the risk of developing leukemia or myelodysplasia
- 3. Prevent and treat infections - antibiotic and antiviral medicines to prevent and treat infections.
- It may take a few months to notice the effects of these medicines. Most often, as blood cell counts rise, symptoms lessen.
- Blood cell counts in people who respond well to these medicines usually don't reach normal levels.
- However, the blood cell counts often are high enough to allow people to do their normal activities.
- "Ticlopidine is Contraindicated in aplastic anemia"
Supportive Care in treatment of aplastic anemia [1] (DONOT EDIT)
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Supportive Care
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Specific Treatment of Aplastic Anaemia: General Comments [1] (DONOT EDIT)
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General Comments
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Specific Treatment of Aplastic Anaemia: Human Leucocyte Antigen (HLA)-identical Sibling Donor Transplantation [1] (DONOT EDIT)
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Human Leucocyte Antigen (HLA)-identical Sibling Donor Transplantation
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Specific Treatment of Aplastic Anaemia: Immunosuppressive Therapy: ATG and Ciclosporin [1] (DONOT EDIT)
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Immunosuppressive Therapy: ATG and Ciclosporin
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Specific Treatment of Aplastic Anaemia: Trial Therapy or Clinical Research Protocols [1] (DONOT EDIT)
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Trial Therapy or Clinical Research Protocols
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Specific Treatment of Aplastic Anaemia: Management of Aplastic Anaemia in the Presence of an Abnormal Cytogenetic Clone [1] (DONOT EDIT)
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Management of Aplastic Anaemia in the Presence of an Abnormal Cytogenetic Clone
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Specific Treatment of Aplastic Anaemia: Management of Aplastic Anaemia in the Presence of an Abnormal Cytogenetic Clone [1] (DONOT EDIT)
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Management of Aplastic Anaemia in the Presence of an Abnormal Cytogenetic Clone
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Specific Treatment of Aplastic Anaemia: Management of Aplastic Anaemia in Pregnancy [1] (DONOT EDIT)
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Management of Aplastic Anaemia in Pregnancy
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