Liposarcoma classification: Difference between revisions

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==Overview==
==Overview==
Liposarcoma is a type of soft tissue malignant tumor that may be classified into well-differentiated, de-differentiated, myxoid, round cell, or pleiomorphic liposarcoma.
Liposarcoma is a type of soft tissue malignant tumor that may be classified into well-differentiated, de-differentiated, myxoid, round cell, or pleomorphic liposarcoma.
 
==Classification==
==Classification==
Liposarcoma is a type of [[soft tissue sarcoma]]s, which accounts for approximately 20% of the [[mesenchymal]] [[malignancies]].  Liposarcomas may be classified into different subtypes, according to their histologic, cytogenetic, biologic, and molecular features.  The [[World Health Organization]] proposed the following classification of liposarcomas:<ref>{{cite book | last = Weiss | first = Sharon | title = Histological typing of soft tissue tumours | publisher = Springer-Verlag | location = Berlin New York | year = 1994 | isbn = 3540567941 }}</ref><ref name="pmid10982304">{{cite journal| author=Dei Tos AP| title=Liposarcoma: new entities and evolving concepts. | journal=Ann Diagn Pathol | year= 2000 | volume= 4 | issue= 4 | pages= 252-66 | pmid=10982304 | doi=10.1053/adpa.2000.8133 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10982304  }} </ref><ref name=WHO>{{cite web |url=http://www.iarc.fr/en/publications/pdfs-online/pat-gen/bb5/bb5-classifsofttissue.pdf |title=WHO Classification of Soft Tissue Tumors |last1= |first1= |last2= |first2= |date= |website=WHO |publisher=WHO |accessdate=Sep 25 2014}}}}</ref>
Liposarcoma is a type of [[soft tissue sarcoma]]s, which accounts for approximately 20% of the [[mesenchymal]] [[malignancies]].  Liposarcomas may be classified into different subtypes, according to their histologic, cytogenetic, biologic, and molecular features.  The [[World Health Organization]] proposed the following classification of liposarcomas:<ref>{{cite book | last = Weiss | first = Sharon | title = Histological typing of soft tissue tumours | publisher = Springer-Verlag | location = Berlin New York | year = 1994 | isbn = 3540567941 }}</ref><ref name="pmid10982304">{{cite journal| author=Dei Tos AP| title=Liposarcoma: new entities and evolving concepts. | journal=Ann Diagn Pathol | year= 2000 | volume= 4 | issue= 4 | pages= 252-66 | pmid=10982304 | doi=10.1053/adpa.2000.8133 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10982304  }} </ref><ref name=WHO>{{cite web |url=http://www.iarc.fr/en/publications/pdfs-online/pat-gen/bb5/bb5-classifsofttissue.pdf |title=WHO Classification of Soft Tissue Tumors |last1= |first1= |last2= |first2= |date= |website=WHO |publisher=WHO |accessdate=Sep 25 2014}}}}</ref>

Revision as of 12:54, 26 August 2015

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: João André Alves Silva, M.D. [2]

Overview

Liposarcoma is a type of soft tissue malignant tumor that may be classified into well-differentiated, de-differentiated, myxoid, round cell, or pleomorphic liposarcoma.

Classification

Liposarcoma is a type of soft tissue sarcomas, which accounts for approximately 20% of the mesenchymal malignancies. Liposarcomas may be classified into different subtypes, according to their histologic, cytogenetic, biologic, and molecular features. The World Health Organization proposed the following classification of liposarcomas:[1][2][3]

WHO Classification of Liposarcoma[3]
  • Well-diferentiated liposarcoma:
  • Adipocytic or lipoma-like
  • Inflammatory
  • Sclerosing
  • De-differentiated liposarcoma
  • Myxoid-round cell liposarcoma (MRCLS)
  • Pleomorphic liposarcoma
  • Liposarcoma, not otherwise specified

References

  1. Weiss, Sharon (1994). Histological typing of soft tissue tumours. Berlin New York: Springer-Verlag. ISBN 3540567941.
  2. Dei Tos AP (2000). "Liposarcoma: new entities and evolving concepts". Ann Diagn Pathol. 4 (4): 252–66. doi:10.1053/adpa.2000.8133. PMID 10982304.
  3. 3.0 3.1 "WHO Classification of Soft Tissue Tumors" (PDF). WHO. WHO. Retrieved Sep 25 2014. Check date values in: |accessdate= (help)}}


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