Endocarditis laboratory findings: Difference between revisions
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== Overivew== | == Overivew== | ||
Laboratory findings consistent with the diagnosis of endocarditis include elevated [[white blood cell count]], [[erythrocyte sedimentation rate]], [[rheumatoid factor]], and elevated [[BUN]] and [[creatinine]] if [[glomerulonephritis]] is present.<ref name="pmid15956145">{{cite journal| author=Baddour LM, Wilson WR, Bayer AS, Fowler VG, Bolger AF, Levison ME et al.| title=Infective endocarditis: diagnosis, antimicrobial therapy, and management of complications: a statement for healthcare professionals from the Committee on Rheumatic Fever, Endocarditis, and Kawasaki Disease, Council on Cardiovascular Disease in the Young, and the Councils on Clinical Cardiology, Stroke, and Cardiovascular Surgery and Anesthesia, American Heart Association: endorsed by the Infectious Diseases Society of America. | journal=Circulation | year= 2005 | volume= 111 | issue= 23 | pages= e394-434 | pmid=15956145 | doi=10.1161/CIRCULATIONAHA.105.165564 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15956145 }} </ref><ref name="pmid11830803">{{cite journal| author=Dhawan VK| title=Infective endocarditis in elderly patients. | journal=Clin Infect Dis | year= 2002 | volume= 34 | issue= 6 | pages= 806-12 | pmid=11830803 | doi=10.1086/339045 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11830803 }} </ref> | |||
==Laboratory Findings== | ==Laboratory Findings== | ||
Revision as of 13:38, 28 September 2015
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Endocarditis Microchapters |
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2014 AHA/ACC Guideline for the Management of Patients With Valvular Heart Disease |
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Endocarditis laboratory findings On the Web |
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Risk calculators and risk factors for Endocarditis laboratory findings |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editors-in-Chief: Cafer Zorkun, M.D., Ph.D. [2]
Overivew
Laboratory findings consistent with the diagnosis of endocarditis include elevated white blood cell count, erythrocyte sedimentation rate, rheumatoid factor, and elevated BUN and creatinine if glomerulonephritis is present.[1][2]
Laboratory Findings
Leukocytosis
- A marked leukocytosis is present.
Erythrocyte Sedimentation Rate
- An elevated erythrocyte sedimentation rate is present.
Rheumatoid Factor
- A positive serum rheumatoid factor may be present and is present in approximately 50% of patients with subacute disease. It becomes negative after successful treatment.
Renal Function
- The serum BUN and creatinine may be elevated if glomerulonephritis is present.
Urinalysis
- Glomerulonephritis may be present.
2008 and Incorporated 2006 ACC/AHA Guidelines for the Management of Patients with Valvular Heart Disease (DO NOT EDIT) [3]
Evaluation (DO NOT EDIT) [3]
| Class I |
| "1. Patients at risk for infective endocarditis who have unexplained fever for more than 48 h should have at least 2 sets of blood cultures obtained from different sites. (Level of Evidence: B)" |
| Class III |
| "1. Patients with known valve disease or a valve prosthesis should not receive antibiotics before blood cultures are obtained for unexplained fever. (Level of Evidence: B)" |
Sources
- 2008 Focused Update Incorporated Into the ACC/AHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease [3]
References
- ↑ Baddour LM, Wilson WR, Bayer AS, Fowler VG, Bolger AF, Levison ME; et al. (2005). "Infective endocarditis: diagnosis, antimicrobial therapy, and management of complications: a statement for healthcare professionals from the Committee on Rheumatic Fever, Endocarditis, and Kawasaki Disease, Council on Cardiovascular Disease in the Young, and the Councils on Clinical Cardiology, Stroke, and Cardiovascular Surgery and Anesthesia, American Heart Association: endorsed by the Infectious Diseases Society of America". Circulation. 111 (23): e394–434. doi:10.1161/CIRCULATIONAHA.105.165564. PMID 15956145.
- ↑ Dhawan VK (2002). "Infective endocarditis in elderly patients". Clin Infect Dis. 34 (6): 806–12. doi:10.1086/339045. PMID 11830803.
- ↑ 3.0 3.1 3.2 Bonow RO, Carabello BA, Chatterjee K; et al. (2008). "2008 Focused update incorporated into the ACC/AHA 2006 guidelines for the management of patients with valvular heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 1998 Guidelines for the Management of Patients With Valvular Heart Disease): endorsed by the Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interventions, and Society of Thoracic Surgeons". Circulation. 118 (15): e523–661. doi:10.1161/CIRCULATIONAHA.108.190748. PMID 18820172. Unknown parameter
|month=ignored (help)