Mast cell leukemia natural history, complications and prognosis: Difference between revisions
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{{CMG}};{{AE}}{{NM}} | {{CMG}};{{AE}}{{NM}} | ||
==Overview== | ==Overview== | ||
Prognosis is generally poor, and the median survival time is less than six months.<ref name="Georgin-LavialleLhermitte2012">{{cite journal|last1=Georgin-Lavialle|first1=S.|last2=Lhermitte|first2=L.|last3=Dubreuil|first3=P.|last4=Chandesris|first4=M.-O.|last5=Hermine|first5=O.|last6=Damaj|first6=G.|title=Mast cell leukemia|journal=Blood|volume=121|issue=8|year=2012|pages=1285–1295|issn=0006-4971|doi=10.1182/blood-2012-07-442400}}</ref> | Prognosis is generally poor, and the median survival time is less than six months.<ref name="Georgin-LavialleLhermitte2012">{{cite journal|last1=Georgin-Lavialle|first1=S.|last2=Lhermitte|first2=L.|last3=Dubreuil|first3=P.|last4=Chandesris|first4=M.-O.|last5=Hermine|first5=O.|last6=Damaj|first6=G.|title=Mast cell leukemia|journal=Blood|volume=121|issue=8|year=2012|pages=1285–1295|issn=0006-4971|doi=10.1182/blood-2012-07-442400}}</ref> | ||
==Natural history== | ==Natural history== | ||
==Complications== | ==Complications== | ||
==Prognosis== | ==Prognosis== | ||
*Mast cell leukemia is by far an incurable disease with an aggressive behavior. | *Mast cell leukemia is by far an incurable disease with an aggressive behavior. | ||
*Prognosis is generally poor, and the median survival time is less than six months.<ref name="Georgin-LavialleLhermitte2012">{{cite journal|last1=Georgin-Lavialle|first1=S.|last2=Lhermitte|first2=L.|last3=Dubreuil|first3=P.|last4=Chandesris|first4=M.-O.|last5=Hermine|first5=O.|last6=Damaj|first6=G.|title=Mast cell leukemia|journal=Blood|volume=121|issue=8|year=2012|pages=1285–1295|issn=0006-4971|doi=10.1182/blood-2012-07-442400}}</ref> | *Prognosis is generally poor, and the median survival time is less than six months.<ref name="Georgin-LavialleLhermitte2012">{{cite journal|last1=Georgin-Lavialle|first1=S.|last2=Lhermitte|first2=L.|last3=Dubreuil|first3=P.|last4=Chandesris|first4=M.-O.|last5=Hermine|first5=O.|last6=Damaj|first6=G.|title=Mast cell leukemia|journal=Blood|volume=121|issue=8|year=2012|pages=1285–1295|issn=0006-4971|doi=10.1182/blood-2012-07-442400}}</ref> | ||
===Prognostic factors=== | ===Prognostic factors=== | ||
*Advanced age | *Advanced age |
Revision as of 15:47, 25 November 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Nawal Muazam M.D.[2]
Overview
Prognosis is generally poor, and the median survival time is less than six months.[1]
Natural history
Complications
Prognosis
- Mast cell leukemia is by far an incurable disease with an aggressive behavior.
- Prognosis is generally poor, and the median survival time is less than six months.[1]
Prognostic factors
- Advanced age
- History of weight loss
- Anemia
- Thrombocytopenia
- Hypoalbuminemia
- Excess of bone marrow blasts