Mast cell leukemia risk factors: Difference between revisions
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{{CMG}};{{AE}}{{NM}} | {{CMG}};{{AE}}{{NM}} | ||
==Overview== | ==Overview== | ||
The risk factor for malignant transformation of systemic mastocytosis to mast cell leukemia is advanced age, history of weight loss, [[anemia]], [[thrombocytopenia]], [[hypoalbuminemia]], and an excess of bone marrow blasts.<ref name="Georgin-LavialleLhermitte2012">{{cite journal|last1=Georgin-Lavialle|first1=S.|last2=Lhermitte|first2=L.|last3=Dubreuil|first3=P.|last4=Chandesris|first4=M.-O.|last5=Hermine|first5=O.|last6=Damaj|first6=G.|title=Mast cell leukemia|journal=Blood|volume=121|issue=8|year=2012|pages=1285–1295|issn=0006-4971|doi=10.1182/blood-2012-07-442400}}</ref> | The risk factor for malignant transformation of [[systemic mastocytosis]] to mast cell leukemia is [[Age|advanced age]], [[Weight loss|history of weight loss]], [[anemia]], [[thrombocytopenia]], [[hypoalbuminemia]], and an excess of bone marrow blasts.<ref name="Georgin-LavialleLhermitte2012">{{cite journal|last1=Georgin-Lavialle|first1=S.|last2=Lhermitte|first2=L.|last3=Dubreuil|first3=P.|last4=Chandesris|first4=M.-O.|last5=Hermine|first5=O.|last6=Damaj|first6=G.|title=Mast cell leukemia|journal=Blood|volume=121|issue=8|year=2012|pages=1285–1295|issn=0006-4971|doi=10.1182/blood-2012-07-442400}}</ref> | ||
==Mast cell leukemia risk factors== | ==Mast cell leukemia risk factors== | ||
The risk factor for malignant transformation of systemic mastocytosis to mast cell leukemia is:<ref name="Georgin-LavialleLhermitte2012">{{cite journal|last1=Georgin-Lavialle|first1=S.|last2=Lhermitte|first2=L.|last3=Dubreuil|first3=P.|last4=Chandesris|first4=M.-O.|last5=Hermine|first5=O.|last6=Damaj|first6=G.|title=Mast cell leukemia|journal=Blood|volume=121|issue=8|year=2012|pages=1285–1295|issn=0006-4971|doi=10.1182/blood-2012-07-442400}}</ref> | The risk factor for malignant transformation of [[systemic mastocytosis]] to mast cell leukemia is:<ref name="Georgin-LavialleLhermitte2012">{{cite journal|last1=Georgin-Lavialle|first1=S.|last2=Lhermitte|first2=L.|last3=Dubreuil|first3=P.|last4=Chandesris|first4=M.-O.|last5=Hermine|first5=O.|last6=Damaj|first6=G.|title=Mast cell leukemia|journal=Blood|volume=121|issue=8|year=2012|pages=1285–1295|issn=0006-4971|doi=10.1182/blood-2012-07-442400}}</ref> | ||
*Advanced age | *[[Age|Advanced age]] | ||
*History of weight loss | *[[Weight loss|History of weight loss]] | ||
*[[Anemia]] | *[[Anemia]] | ||
*[[Thrombocytopenia]] | *[[Thrombocytopenia]] | ||
Revision as of 15:00, 2 December 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Nawal Muazam M.D.[2]
Overview
The risk factor for malignant transformation of systemic mastocytosis to mast cell leukemia is advanced age, history of weight loss, anemia, thrombocytopenia, hypoalbuminemia, and an excess of bone marrow blasts.[1]
Mast cell leukemia risk factors
The risk factor for malignant transformation of systemic mastocytosis to mast cell leukemia is:[1]
- Advanced age
- History of weight loss
- Anemia
- Thrombocytopenia
- Hypoalbuminemia
- An excess of bone marrow blasts