Uveitis classification: Difference between revisions

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== Classification ==
== Classification ==
Uveitis can be described according to the following classifications:<ref name="pmid18379933">{{cite journal| author=Deschenes J, Murray PI, Rao NA, Nussenblatt RB, International Uveitis Study Group| title=International Uveitis Study Group (IUSG): clinical classification of uveitis. | journal=Ocul Immunol Inflamm | year= 2008 | volume= 16 | issue= 1 | pages= 1-2 | pmid=18379933 | doi=10.1080/09273940801899822 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18379933  }} </ref><ref name="pmid16196117">{{cite journal| author=Jabs DA, Nussenblatt RB, Rosenbaum JT, Standardization of Uveitis Nomenclature (SUN) Working Group| title=Standardization of uveitis nomenclature for reporting clinical data. Results of the First International Workshop. | journal=Am J Ophthalmol | year= 2005 | volume= 140 | issue= 3 | pages= 509-16 | pmid=16196117 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16196117  }} </ref>
*'''Classification by Anatomical Location'''
*'''Classification by Anatomical Location'''
** '''Anterior uveitis''' involves inflammation in the front part of the eye. It is the most common form of uveitis, making up 40-70% of all uveitis cases<ref>http://www.preventblindness.org/uveitis/what/types.html</ref>.  It is often called [[iritis]] because it is usually only effects the [[iris]].
** '''Anterior uveitis''': Iritis, cyclitis or iridocyclitis. Inflammation affecting, the [[iris]], the [[ciliary body]], or both.
** '''[[Intermediate uveitis]]''' (also known as '''cyclitis''', '''pars planitis''', or '''vitritis''') involves inflammation of the [[ciliary body]], the [[vitreous humor]], and the front end of the [[retina]].  This is the least common form of uveitis, constituting 7-15% of cases<ref>http://www.preventblindness.org/uveitis/what/types.html</ref>.
** '''[[Intermediate uveitis]]''': Viritis or  pars planitis. Inflammation of the the [[vitreous humor]] or the [[pars plana]].
** '''Posterior uveitis''' (also known as '''choroiditis''' if just the [[choroid]] is involved, or '''[[chorioretinitis]]''' if the retina is also involved) affects the back part of the [[uvea]] and involves primarily the [[choroid]], a layer of [[blood vessels]] and [[connective tissue]] in the middle part of the eye. It can also involve inflammation of the [[retina]] and [[optic nerve]].  It makes up 15-22% of all uveitis cases<ref>http://www.preventblindness.org/uveitis/what/types.html</ref>.
** '''Posterior uveitis''': [[Choroiditis]], [[retinitis]], or [[chorioretinitis]]. Inflammation of the choroid, the retina, or both.
** '''Panuveitis''' is the inflammation of the entire [[uvea]], and it effects all layers of the [[uvea]].
** '''Panuveitis''': Inflammation of the entire [[uvea]].  
* '''Classification by Duration of Symptoms'''
* '''Classification by Duration of Symptoms'''<ref name="pmid10688564">{{cite journal| author=McCluskey PJ, Towler HM, Lightman S| title=Management of chronic uveitis. | journal=BMJ | year= 2000 | volume= 320 | issue= 7234 | pages= 555-8 | pmid=10688564 | doi= | pmc=1117601 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10688564  }} </ref>
** '''Acute'''
** '''Acute''': Active uveitis for less than 3 months.
** '''Chronic'''
** '''Chronic''': Active uveitis for more than 3 months.
* '''Classification by type of inflammation'''
* '''Classification by type of inflammation'''<ref name="pmid17311570">{{cite journal| author=Gutteridge IF, Hall AJ| title=Acute anterior uveitis in primary care. | journal=Clin Exp Optom | year= 2007 | volume= 90 | issue= 2 | pages= 70-82 | pmid=17311570 | doi=10.1111/j.1444-0938.2006.00128.x | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17311570  }} </ref>
** '''Granulomatous'''
** '''Granulomatous''': showing granulomatous inflammation on slit lamp test
** '''Non-granulomatous'''
** '''Non-granulomatous''' showing no granulomatous inflammation on slit lamp test
* '''Classification by Laterality'''
* '''Classification by Laterality'''
** '''Unilateral'''
** '''Unilateral''': Single eye involvement
** '''Bilateral'''
** '''Bilateral''': Both eyes involvement
* '''Classification by Etiology'''
* '''Classification by Etiology'''<ref name="pmid18379933">{{cite journal| author=Deschenes J, Murray PI, Rao NA, Nussenblatt RB, International Uveitis Study Group| title=International Uveitis Study Group (IUSG): clinical classification of uveitis. | journal=Ocul Immunol Inflamm | year= 2008 | volume= 16 | issue= 1 | pages= 1-2 | pmid=18379933 | doi=10.1080/09273940801899822 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18379933  }} </ref><ref name="pmid16196117">{{cite journal| author=Jabs DA, Nussenblatt RB, Rosenbaum JT, Standardization of Uveitis Nomenclature (SUN) Working Group| title=Standardization of uveitis nomenclature for reporting clinical data. Results of the First International Workshop. | journal=Am J Ophthalmol | year= 2005 | volume= 140 | issue= 3 | pages= 509-16 | pmid=16196117 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16196117  }} </ref>
** '''Idiopathic'''
** '''Idiopathic''': No known cause
** '''Infectious'''
** '''Infectious''': Bacterial, viral, fungal, or parasitic cause
** '''Autoimmune'''
** '''Autoimmune/Inflammatory''': Caused by a systemic non-infectious inflammatory condition commonly associated with uveitis
** '''Drug-Induced'''
** '''Drug-Induced''': Iatrogenic cause by medications that are associated with incidence of uveitis
==References==
{{reflist|2}}
 
[[Category:Ophthalmology]]
[[Category:Primary care]]
 
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==References==
==References==

Revision as of 19:35, 26 July 2016

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Uveitis is best described using various, concurrent classification systems. Uveitis may be classified according to anatomical location into 4 subtypes, depending on which part of the uvea is primarily affected: anterior, intermediate, posterior, and panuveitis. Based on the duration of symptoms it may be further sub-classified as acute or chronic. Upon further investigation, uveitis may be classified according to histological features of the inflammation such as granulomatous or non-granulomatous. Additionally, uveitis may be described by the laterality of the condition (unilateral or bilateral). Finally, uveitis may be classified by general underlying systemic causes such as infectious, autoimmune, drug-induced, or idiopathic.

Classification

Uveitis can be described according to the following classifications:[1][2]

  • Classification by Anatomical Location
  • Classification by Duration of Symptoms[3]
    • Acute: Active uveitis for less than 3 months.
    • Chronic: Active uveitis for more than 3 months.
  • Classification by type of inflammation[4]
    • Granulomatous: showing granulomatous inflammation on slit lamp test
    • Non-granulomatous showing no granulomatous inflammation on slit lamp test
  • Classification by Laterality
    • Unilateral: Single eye involvement
    • Bilateral: Both eyes involvement
  • Classification by Etiology[1][2]
    • Idiopathic: No known cause
    • Infectious: Bacterial, viral, fungal, or parasitic cause
    • Autoimmune/Inflammatory: Caused by a systemic non-infectious inflammatory condition commonly associated with uveitis
    • Drug-Induced: Iatrogenic cause by medications that are associated with incidence of uveitis

References

  1. 1.0 1.1 Deschenes J, Murray PI, Rao NA, Nussenblatt RB, International Uveitis Study Group (2008). "International Uveitis Study Group (IUSG): clinical classification of uveitis". Ocul Immunol Inflamm. 16 (1): 1–2. doi:10.1080/09273940801899822. PMID 18379933.
  2. 2.0 2.1 Jabs DA, Nussenblatt RB, Rosenbaum JT, Standardization of Uveitis Nomenclature (SUN) Working Group (2005). "Standardization of uveitis nomenclature for reporting clinical data. Results of the First International Workshop". Am J Ophthalmol. 140 (3): 509–16. PMID 16196117.
  3. McCluskey PJ, Towler HM, Lightman S (2000). "Management of chronic uveitis". BMJ. 320 (7234): 555–8. PMC 1117601. PMID 10688564.
  4. Gutteridge IF, Hall AJ (2007). "Acute anterior uveitis in primary care". Clin Exp Optom. 90 (2): 70–82. doi:10.1111/j.1444-0938.2006.00128.x. PMID 17311570.

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References

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