Uveitis classification: Difference between revisions
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==Overview== | ==Overview== | ||
Uveitis is best described using various, concurrent classification systems. Uveitis may be classified according to anatomical location into 4 subtypes, depending on which part of the [[uvea]] is primarily affected: anterior, intermediate, posterior, and panuveitis. Based on the duration of symptoms it may be further sub-classified as acute or chronic. Upon further investigation, uveitis may be classified according to histological features of the inflammation such as granulomatous or non-granulomatous. Additionally, uveitis may be described by the laterality of the condition (unilateral or bilateral). Finally, uveitis may be classified by general underlying systemic causes such as infectious, autoimmune, drug-induced, or idiopathic. | Uveitis is best described using various, concurrent classification systems. Uveitis may be classified according to anatomical location into 4 subtypes, depending on which part of the [[uvea]] is primarily affected: anterior, intermediate, posterior, and panuveitis. Based on the duration of symptoms it may be further sub-classified as acute or chronic. Upon further investigation, uveitis may be classified according to histological features of the inflammation such as granulomatous or non-granulomatous. Additionally, uveitis may be described by the laterality of the condition (unilateral or bilateral). Finally, uveitis may be classified by general underlying systemic causes such as infectious, autoimmune, drug-induced, or idiopathic.<ref name="pmid18379933">{{cite journal| author=Deschenes J, Murray PI, Rao NA, Nussenblatt RB, International Uveitis Study Group| title=International Uveitis Study Group (IUSG): clinical classification of uveitis. | journal=Ocul Immunol Inflamm | year= 2008 | volume= 16 | issue= 1 | pages= 1-2 | pmid=18379933 | doi=10.1080/09273940801899822 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18379933 }} </ref><ref name="pmid16196117">{{cite journal| author=Jabs DA, Nussenblatt RB, Rosenbaum JT, Standardization of Uveitis Nomenclature (SUN) Working Group| title=Standardization of uveitis nomenclature for reporting clinical data. Results of the First International Workshop. | journal=Am J Ophthalmol | year= 2005 | volume= 140 | issue= 3 | pages= 509-16 | pmid=16196117 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16196117 }} </ref><ref name="pmid10688564">{{cite journal| author=McCluskey PJ, Towler HM, Lightman S| title=Management of chronic uveitis. | journal=BMJ | year= 2000 | volume= 320 | issue= 7234 | pages= 555-8 | pmid=10688564 | doi= | pmc=1117601 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10688564 }} </ref><ref name="pmid17311570">{{cite journal| author=Gutteridge IF, Hall AJ| title=Acute anterior uveitis in primary care. | journal=Clin Exp Optom | year= 2007 | volume= 90 | issue= 2 | pages= 70-82 | pmid=17311570 | doi=10.1111/j.1444-0938.2006.00128.x | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17311570 }} </ref> | ||
== Classification == | == Classification == | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Uveitis is best described using various, concurrent classification systems. Uveitis may be classified according to anatomical location into 4 subtypes, depending on which part of the uvea is primarily affected: anterior, intermediate, posterior, and panuveitis. Based on the duration of symptoms it may be further sub-classified as acute or chronic. Upon further investigation, uveitis may be classified according to histological features of the inflammation such as granulomatous or non-granulomatous. Additionally, uveitis may be described by the laterality of the condition (unilateral or bilateral). Finally, uveitis may be classified by general underlying systemic causes such as infectious, autoimmune, drug-induced, or idiopathic.[1][2][3][4]
Classification
Uveitis can be described according to the following classifications:[1][2]
- Classification by Anatomical Location
- Anterior uveitis: Iritis, cyclitis or iridocyclitis. Inflammation affecting, the iris, the ciliary body, or both.
- Intermediate uveitis: Viritis or pars planitis. Inflammation of the the vitreous humor or the pars plana.
- Posterior uveitis: Choroiditis, retinitis, or chorioretinitis. Inflammation of the choroid, the retina, or both.
- Panuveitis: Inflammation of the entire uvea.
- Classification by Duration of Symptoms[3]
- Acute: Active uveitis for less than 3 months.
- Chronic: Active uveitis for more than 3 months.
- Classification by type of inflammation[4]
- Granulomatous: showing granulomatous inflammation on slit lamp test
- Non-granulomatous showing no granulomatous inflammation on slit lamp test
- Classification by Laterality
- Unilateral: Single eye involvement
- Bilateral: Both eyes involvement
- Classification by Etiology[1][2]
- Idiopathic: No known cause
- Infectious: Bacterial, viral, fungal, or parasitic cause
- Autoimmune/Inflammatory: Caused by a systemic non-infectious inflammatory condition commonly associated with uveitis
- Drug-Induced: Iatrogenic cause by medications that are associated with incidence of uveitis
References
- ↑ 1.0 1.1 1.2 Deschenes J, Murray PI, Rao NA, Nussenblatt RB, International Uveitis Study Group (2008). "International Uveitis Study Group (IUSG): clinical classification of uveitis". Ocul Immunol Inflamm. 16 (1): 1–2. doi:10.1080/09273940801899822. PMID 18379933.
- ↑ 2.0 2.1 2.2 Jabs DA, Nussenblatt RB, Rosenbaum JT, Standardization of Uveitis Nomenclature (SUN) Working Group (2005). "Standardization of uveitis nomenclature for reporting clinical data. Results of the First International Workshop". Am J Ophthalmol. 140 (3): 509–16. PMID 16196117.
- ↑ 3.0 3.1 McCluskey PJ, Towler HM, Lightman S (2000). "Management of chronic uveitis". BMJ. 320 (7234): 555–8. PMC 1117601. PMID 10688564.
- ↑ 4.0 4.1 Gutteridge IF, Hall AJ (2007). "Acute anterior uveitis in primary care". Clin Exp Optom. 90 (2): 70–82. doi:10.1111/j.1444-0938.2006.00128.x. PMID 17311570.