Hemophilia A history and symptoms: Difference between revisions
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==Symptoms== | ==Symptoms== | ||
Mild hemophilia is usually asymptomatic, unless the patient experiences an injury or undergoes surgery. Young males often experience excessive bleeding with circumcision, or following dental procedures. | |||
Hemophilia leads to a severely increased risk of bleeding from common injuries. The sites of bleeding are: | Hemophilia leads to a severely increased risk of bleeding from common injuries. The sites of bleeding are: | ||
* [[Joint]]s | * [[Joint]]s | ||
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*Spontaneous bleeding | *Spontaneous bleeding | ||
The muscle and joint [[Bleeding|hemorrhages]] are quite typical of hemophilia, while digestive tract and cerebral hemorrhages are also germane to other coagulation disorders. | The muscle and joint [[Bleeding|hemorrhages]] are quite typical of hemophilia, while digestive tract and cerebral hemorrhages are also germane to other coagulation disorders. Bleeding into large joints or muscles is the most common site of bleeding in hemophilia. Most common muscle bleeds include the muscles of the upper arm and forearm, the iliopsoas muscle, the thigh and the calf. Most joint bleeds affect the knees, ankles or elbows. Patients may present with pain in these areas, or they may simply present with incidental bruising or swelling. Repeated episodes of bleeds into joints may result in arthritis, and eventual destruction of cartilage in joint space. | ||
Though uncommon, spontaneous or traumatic intracranial hemorrhages are the most catastrophic complication of hemophilia. Patients with intracranial hemorrhages present with typical symptoms, including nausea, headache, vomiting, and altered mental status. This is a medical emergency. | |||
==References== | ==References== | ||
Revision as of 21:57, 29 July 2016
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Overview
History
A family history of abnormal bleeding is often present and highly suggestive of hemophilia A, though it is not essential for diagnosis
Symptoms
Mild hemophilia is usually asymptomatic, unless the patient experiences an injury or undergoes surgery. Young males often experience excessive bleeding with circumcision, or following dental procedures. Hemophilia leads to a severely increased risk of bleeding from common injuries. The sites of bleeding are:
Other symptoms include:
- Bruising
- Excessive bleeding following circumcision
- Gastrointestinal tract and urinary tract hemorrhage
- Nosebleeds
- Prolonged bleeding from cuts, tooth extraction, and surgery
- Spontaneous bleeding
The muscle and joint hemorrhages are quite typical of hemophilia, while digestive tract and cerebral hemorrhages are also germane to other coagulation disorders. Bleeding into large joints or muscles is the most common site of bleeding in hemophilia. Most common muscle bleeds include the muscles of the upper arm and forearm, the iliopsoas muscle, the thigh and the calf. Most joint bleeds affect the knees, ankles or elbows. Patients may present with pain in these areas, or they may simply present with incidental bruising or swelling. Repeated episodes of bleeds into joints may result in arthritis, and eventual destruction of cartilage in joint space. Though uncommon, spontaneous or traumatic intracranial hemorrhages are the most catastrophic complication of hemophilia. Patients with intracranial hemorrhages present with typical symptoms, including nausea, headache, vomiting, and altered mental status. This is a medical emergency.