Uveitis natural history, complications and prognosis: Difference between revisions
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* Rapid initiation of corticosteroid treatment | * Rapid initiation of corticosteroid treatment | ||
* Good initial visual acuity | * Good initial visual acuity | ||
* Good response to corticosteroid or anti-TNF therapy | |||
* | |||
The following are poor prognostic factors:<br> | The following are poor prognostic factors:<br> | ||
* Chronic disease course | * Chronic disease course | ||
* Posterior or intermediate uveitis | * Posterior or intermediate uveitis | ||
* Lack of response to corticosteroid | * Lack of response to corticosteroid or anti-TNF therapy | ||
* Complications of uveitis | * Complications of uveitis | ||
* Poor initial visual acuity | * Poor initial visual acuity | ||
* Isolated ocular uveitis (no underlying systemic disease) | |||
With | With appropriate treatment, most attacks of anterior uveitis go away in a few days to weeks. However, relapses are common. Inflammation related to posterior uveitis may last from months to years and may cause permanent vision damage, even with treatment. | ||
== References == | == References == | ||
Revision as of 23:00, 1 August 2016
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Tarek Nafee, M.D. [2]
Overview
If left untreated, uveitis can progress to permanent vision loss. Complications of uveitis include cataracts, glaucoma, macular edema, and retinal detachment.
Natural history
If left untreated, uveitis can progress to permanent vision loss. Uveitis is estimated to be responsible for approximately 10% of the blindness in the western world.[1][2][3]
Complications
Possible complications of uveitis include:[4][5]
Prognosis
The prognosis of uveitis varies with the subtype, etiology, severity, duration and responsiveness to treatment.[6]
The following are favorable prognostic factors:
- Rapid initiation of corticosteroid treatment
- Good initial visual acuity
- Good response to corticosteroid or anti-TNF therapy
The following are poor prognostic factors:
- Chronic disease course
- Posterior or intermediate uveitis
- Lack of response to corticosteroid or anti-TNF therapy
- Complications of uveitis
- Poor initial visual acuity
- Isolated ocular uveitis (no underlying systemic disease)
With appropriate treatment, most attacks of anterior uveitis go away in a few days to weeks. However, relapses are common. Inflammation related to posterior uveitis may last from months to years and may cause permanent vision damage, even with treatment.
References
- ↑ McCluskey PJ, Towler HM, Lightman S (2000). "Management of chronic uveitis". BMJ. 320 (7234): 555–8. PMC 1117601. PMID 10688564.
- ↑ Rothova A, Suttorp-van Schulten MS, Frits Treffers W, Kijlstra A (1996). "Causes and frequency of blindness in patients with intraocular inflammatory disease". Br J Ophthalmol. 80 (4): 332–6. PMC 505460. PMID 8703885.
- ↑ Nussenblatt RB (1990). "The natural history of uveitis". Int Ophthalmol. 14 (5–6): 303–8. PMID 2249907.
- ↑ Dick AD, Tundia N, Sorg R, Zhao C, Chao J, Joshi A; et al. (2016). "Risk of Ocular Complications in Patients with Noninfectious Intermediate Uveitis, Posterior Uveitis, or Panuveitis". Ophthalmology. 123 (3): 655–62. doi:10.1016/j.ophtha.2015.10.028. PMID 26712559.
- ↑ Maini R, O'Sullivan J, Reddy A, Watson S, Edelsten C (2004). "The risk of complications of uveitis in a district hospital cohort". Br J Ophthalmol. 88 (4): 512–7. PMC 1772087. PMID 15031168.
- ↑ Prognosis of Uveitis (2010)http://www.intelihealth.com/IH/ihtIH/EMIHC000/9339/10942.html