Uveitis laboratory findings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Tarek Nafee, M.D. [2]

Overview

There are no diagnostic lab findings associated with uveitis. The presence of certain non-specific laboratory findings, in the presence of uveitis, may be suggestive of certain underlying causes.

Laboratory findings

There are no diagnostic lab findings associated with uveitis. The presence of certain non-specific laboratory findings, in the presence of uveitis, may be suggestive of certain underlying causes such as:

White blood cells

• Elevated white blood cells with a left shift may be suggestive of an underlying infection.
• Decreased white blood cell count may be indicative of an immunosuppressed state.

ESR and CRP

• Elevated ESR and CRP may be suggestive of an underlying infection or inflammatory condition.

CBC and differentials

• A low hematocrit with microcytosis or marginal normocytosis may be indicative of blood loss by inflammatory bowel disease, or any chronic inflammatory disorder.

Iron studies

• Low ferritin with a high TIBC is suggestive of chronic blood loss by inflammatory bowel disease.
• High ferritin may be suggestive of anemia of chronic inflammatory conditions.

HLA subtyping

• HLA-B27
• HLA-A29
• HLA-B9
• HLA-B15

All associated with different underlying conditions of uveitis.

References

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