Acute retinal necrosis epidemiology and demographics: Difference between revisions
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==Overview== | ==Overview== | ||
Research in the United Kingdom resulted in an estimated incidence of approximately 6.3 per 100,000 individuals. Acute retinal necrosis (ARN) developed from [[Herpes simplex virus]] 1 and [[Varicella-zoster virus]] is most common among patients older than 50 years, while the incidence of HSV-2 caused ARN is highest in children and young adults between age 9 and 22 years. There is no racial or gender predisposition to Acute retinal necrosis. | Research in the United Kingdom resulted in an estimated incidence of approximately 6.3 per 100,000 individuals. Acute [[retinal]] [[necrosis]] (ARN) developed from [[Herpes simplex virus]] 1 and [[Varicella-zoster virus]] is most common among patients older than 50 years, while the incidence of HSV-2 caused ARN is highest in children and young adults between age 9 and 22 years. There is no racial or gender predisposition to Acute [[retinal]] [[necrosis]]. | ||
==Epidemiology and Demographics== | ==Epidemiology and Demographics== | ||
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*Research in the United Kingdom resulted in an estimated incidence of approximately 6.3 per 100,000 individuals.<ref name="pmid22281865">{{cite journal |vauthors=Cochrane TF, Silvestri G, McDowell C, Foot B, McAvoy CE |title=Acute retinal necrosis in the United Kingdom: results of a prospective surveillance study |journal=Eye (Lond) |volume=26 |issue=3 |pages=370–7; quiz 378 |year=2012 |pmid=22281865 |pmc=3298997 |doi=10.1038/eye.2011.338 |url=}}</ref> | *Research in the United Kingdom resulted in an estimated incidence of approximately 6.3 per 100,000 individuals.<ref name="pmid22281865">{{cite journal |vauthors=Cochrane TF, Silvestri G, McDowell C, Foot B, McAvoy CE |title=Acute retinal necrosis in the United Kingdom: results of a prospective surveillance study |journal=Eye (Lond) |volume=26 |issue=3 |pages=370–7; quiz 378 |year=2012 |pmid=22281865 |pmc=3298997 |doi=10.1038/eye.2011.338 |url=}}</ref> | ||
**There is evidence that this incidence is underestimated due to biases in case adjudication and under-reporting of data.<ref name="pmid17504853">{{cite journal |vauthors=Muthiah MN, Michaelides M, Child CS, Mitchell SM |title=Acute retinal necrosis: a national population-based study to assess the incidence, methods of diagnosis, treatment strategies and outcomes in the UK |journal=Br J Ophthalmol |volume=91 |issue=11 |pages=1452–5 |year=2007 |pmid=17504853 |pmc=2095441 |doi=10.1136/bjo.2007.114884 |url=}}</ref> | **There is evidence that this incidence is underestimated due to biases in case adjudication and under-reporting of data.<ref name="pmid17504853">{{cite journal |vauthors=Muthiah MN, Michaelides M, Child CS, Mitchell SM |title=Acute retinal necrosis: a national population-based study to assess the incidence, methods of diagnosis, treatment strategies and outcomes in the UK |journal=Br J Ophthalmol |volume=91 |issue=11 |pages=1452–5 |year=2007 |pmid=17504853 |pmc=2095441 |doi=10.1136/bjo.2007.114884 |url=}}</ref> | ||
*Worldwide, the increase of [[immunocompromised]] and aged populations in most countries evidences an increase in Acute retinal necrosis. | *Worldwide, the increase of [[immunocompromised]] and aged populations in most countries evidences an increase in Acute [[retinal]] [[necrosis]]. | ||
===Age=== | ===Age=== | ||
*Acute retinal necrosis (ARN) developed from [[Herpes simplex virus]] 1 and [[Varicella-zoster virus]] is most common among patients older than 50 years.<ref name="pmid25356955">{{cite journal |vauthors=Brydak-Godowska J, Borkowski P, Szczepanik S, Moneta-Wielgoś J, Kęcik D |title=Clinical manifestation of self-limiting acute retinal necrosis |journal=Med. Sci. Monit. |volume=20 |issue= |pages=2088–96 |year=2014 |pmid=25356955 |pmc=4226315 |doi=10.12659/MSM.890469 |url=}}</ref> | *Acute [[retinal]] [[necrosis]] (ARN) developed from [[Herpes simplex virus]] 1 and [[Varicella-zoster virus]] is most common among patients older than 50 years.<ref name="pmid25356955">{{cite journal |vauthors=Brydak-Godowska J, Borkowski P, Szczepanik S, Moneta-Wielgoś J, Kęcik D |title=Clinical manifestation of self-limiting acute retinal necrosis |journal=Med. Sci. Monit. |volume=20 |issue= |pages=2088–96 |year=2014 |pmid=25356955 |pmc=4226315 |doi=10.12659/MSM.890469 |url=}}</ref> | ||
*[[Herpes simplex virus]] (HSV) 2 infection is more common among children and adolescents; the incidence of HSV-2 caused ARN is highest in children and young adults between age 9 and 22 years. | *[[Herpes simplex virus]] (HSV) 2 infection is more common among children and adolescents; the incidence of HSV-2 caused ARN is highest in children and young adults between age 9 and 22 years. | ||
===Gender=== | ===Gender=== | ||
*There is no gender predisposition to Acute retinal necrosis. | *There is no gender predisposition to Acute [[retinal]] [[necrosis]]. | ||
===Race=== | ===Race=== | ||
*There is no racial predisposition to Acute retinal necrosis. | *There is no racial predisposition to Acute [[retinal]] [[necrosis]]. | ||
==References== | ==References== | ||
Revision as of 14:22, 26 August 2016
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Luke Rusowicz-Orazem, B.S.
Overview
Research in the United Kingdom resulted in an estimated incidence of approximately 6.3 per 100,000 individuals. Acute retinal necrosis (ARN) developed from Herpes simplex virus 1 and Varicella-zoster virus is most common among patients older than 50 years, while the incidence of HSV-2 caused ARN is highest in children and young adults between age 9 and 22 years. There is no racial or gender predisposition to Acute retinal necrosis.
Epidemiology and Demographics
Incidence
- Research in the United Kingdom resulted in an estimated incidence of approximately 6.3 per 100,000 individuals.[1]
- There is evidence that this incidence is underestimated due to biases in case adjudication and under-reporting of data.[2]
- Worldwide, the increase of immunocompromised and aged populations in most countries evidences an increase in Acute retinal necrosis.
Age
- Acute retinal necrosis (ARN) developed from Herpes simplex virus 1 and Varicella-zoster virus is most common among patients older than 50 years.[3]
- Herpes simplex virus (HSV) 2 infection is more common among children and adolescents; the incidence of HSV-2 caused ARN is highest in children and young adults between age 9 and 22 years.
Gender
Race
References
- ↑ Cochrane TF, Silvestri G, McDowell C, Foot B, McAvoy CE (2012). "Acute retinal necrosis in the United Kingdom: results of a prospective surveillance study". Eye (Lond). 26 (3): 370–7, quiz 378. doi:10.1038/eye.2011.338. PMC 3298997. PMID 22281865.
- ↑ Muthiah MN, Michaelides M, Child CS, Mitchell SM (2007). "Acute retinal necrosis: a national population-based study to assess the incidence, methods of diagnosis, treatment strategies and outcomes in the UK". Br J Ophthalmol. 91 (11): 1452–5. doi:10.1136/bjo.2007.114884. PMC 2095441. PMID 17504853.
- ↑ Brydak-Godowska J, Borkowski P, Szczepanik S, Moneta-Wielgoś J, Kęcik D (2014). "Clinical manifestation of self-limiting acute retinal necrosis". Med. Sci. Monit. 20: 2088–96. doi:10.12659/MSM.890469. PMC 4226315. PMID 25356955.