Lymphangitis laboratory findings: Difference between revisions
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*Elevated [[white blood cells]] with a [[left shift]] may be suggestive of an underlying infection. | *Elevated [[white blood cells]] with a [[left shift]] may be suggestive of an underlying infection. | ||
*Microfilariae on Giemsa stained, thin and thick blood film smears, are considered gold standard in diagnosis for Filariasis | *Microfilariae on Giemsa stained, thin and thick blood film smears, are considered gold standard in diagnosis for Filariasis | ||
===Laboratory Findings of Severe Disease <small><small><small><small>'''Adapted from the 2005 IDSA Practice guidelines for the diagnosis and management of skin and soft-tissue infections.'''<ref name="pmid16231249">{{cite journal| author=Stevens DL, Bisno AL, Chambers HF, Everett ED, Dellinger P, Goldstein EJ et al.| title=Practice guidelines for the diagnosis and management of skin and soft-tissue infections. | journal=Clin Infect Dis | year= 2005 | volume= 41 | issue= 10 | pages= 1373-406 | pmid=16231249 | doi=10.1086/497143 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16231249 }} </ref></small></small></small></small>=== | |||
*[[C reactive protein]] over 13 mg/L | |||
*[[CBC]] with marked [[left shift]] | |||
*Elevated [[creatinine]] level | |||
*2 to 3 times the upper level of normal [[creatinine phosphokinase]] | |||
*Low [[bicarbonate]] level | |||
===ESR and CRP=== | ===ESR and CRP=== | ||
*Elevated [[ESR]] and [[CRP]] may be suggestive of an underlying infection or [[Autoimmune|inflammatory condition]] | *Elevated [[ESR]] and [[CRP]] may be suggestive of an underlying infection or [[Autoimmune|inflammatory condition]] | ||
Revision as of 16:16, 18 October 2016
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Vishal Devarkonda, M.B.B.S[2]
Overview
There are no diagnostic lab findings associated with lymphangitis. The presence of certain non-specific laboratory findings, in the presence of lymphangitis, may be suggestive of certain underlying causes. Examples of tests that may demonstrate abnormal findings include CBC, ESR, CRP, and serology titers.
Laboratory Findings
There are no diagnostic lab findings associated with lymphangitis The presence of certain non-specific laboratory findings, in the presence of uveitis, may be suggestive of certain underlying causes. Routine laboratory studies should be correlated with a carefully collected history and a precise physical examination. Routine laboratory tests that may be ordered and their respective findings include:
Complete Blood Count with Differentials and Peripheral Blood Smear
- Eosinophilia may be suggestive of underlying parasitic infections.
- Elevated white blood cells with a left shift may be suggestive of an underlying infection.
- Microfilariae on Giemsa stained, thin and thick blood film smears, are considered gold standard in diagnosis for Filariasis
Laboratory Findings of Severe Disease Adapted from the 2005 IDSA Practice guidelines for the diagnosis and management of skin and soft-tissue infections.[1]
- C reactive protein over 13 mg/L
- CBC with marked left shift
- Elevated creatinine level
- 2 to 3 times the upper level of normal creatinine phosphokinase
- Low bicarbonate level
ESR and CRP
- Elevated ESR and CRP may be suggestive of an underlying infection or inflammatory condition
Serology tests
- F. tularensis titre
- Histoplasma titre
Microbiological investigations
- Swab and aspirate taken from the primary site, should be sent for microscopy as well as cultural and sensitivity.
- Microbiological investigations not only helps us to identify causative infectious organism, but also act as a guide to select appropriate antimicrobial
Other Laboratory Findings
- Rarely, Polymerase chain reaction(PCR) can be used in diagnosis of Nocardia, Tularemia, and Leshmania.
References
- ↑ Stevens DL, Bisno AL, Chambers HF, Everett ED, Dellinger P, Goldstein EJ; et al. (2005). "Practice guidelines for the diagnosis and management of skin and soft-tissue infections". Clin Infect Dis. 41 (10): 1373–406. doi:10.1086/497143. PMID 16231249.