Graves' disease diagnostic approach: Difference between revisions
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{{CMG}};{{AE}}{{MehdiP}} | {{CMG}};{{AE}}{{MehdiP}} | ||
==Overview== | ==Overview== | ||
A diagnostic approach to evaluate a suspect patient with clinical symptoms of hyperthyrodism must be done in order to make an accurate diagnosis. | |||
==Diagnostic approach== | ==Diagnostic approach== | ||
*In the presence of relative clinical symptoms and signs for hyperthyroidism, a diagnostic approach must be taken to address accurate diagnosis and start the management. | *In the presence of relative clinical symptoms and signs for hyperthyroidism, a diagnostic approach must be taken to address accurate diagnosis and start the management. | ||
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==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
[[Category: | [[Category:Endocrinology]] | ||
[[Category:Medicine]] | |||
[[Category:Primary care]] | |||
{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} |
Revision as of 18:43, 19 December 2016
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Seyedmahdi Pahlavani, M.D. [2]
Overview
A diagnostic approach to evaluate a suspect patient with clinical symptoms of hyperthyrodism must be done in order to make an accurate diagnosis.
Diagnostic approach
- In the presence of relative clinical symptoms and signs for hyperthyroidism, a diagnostic approach must be taken to address accurate diagnosis and start the management.
- Following algorithm summarizes the diagnostic approach to a suspected hyperthyroid patient.
Suspected Graves' disease | |||||||||||||||||||||||||||||||||||||||||||||||||||||||
Measure serum TSH and free T4 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||
Normal TSH & free T4 | ↓ TSH & ↑ free T4 | ↓ TSH & Normal free T4 | Normal or ↑ TSH & ↑ free T4 | ||||||||||||||||||||||||||||||||||||||||||||||||||||
Hyperthyroidism ruled out | Hyperthyrodism | Measure free T3 | TSH secreting pituitary tumor, Thyroid hormone resistance or Assay interference | ||||||||||||||||||||||||||||||||||||||||||||||||||||
Measure TSH receptor antibodies | |||||||||||||||||||||||||||||||||||||||||||||||||||||||
↑ free T3 | Normal free T3 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
Present | Absent | T3 Toxicosis | Sub-clinical Hyperthyrodism | ||||||||||||||||||||||||||||||||||||||||||||||||||||
Graves' Disease | Assess radioiodine uptake obtain radionuclide scan or both | Evolving Graves' disease Evolving toxic nodular goiter Excess thyroid hormone intake Non thyroidal illness | |||||||||||||||||||||||||||||||||||||||||||||||||||||
Homogeneous increased uptake | Patchy uptake or single nodule | Low or no uptake | |||||||||||||||||||||||||||||||||||||||||||||||||||||
Graves' disease | Toxic nodular goiter | Subacute thyroiditis Excess thyroid hormone intake HCG secreting tumor | |||||||||||||||||||||||||||||||||||||||||||||||||||||