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==Overview==
==Overview==
Depending on etiologies, lymphangitis has spectrum of clinical presentation. Specific history and symptoms for individual infections are discussed in detail separately.<ref name=lymphangitis>lymphanitis Mandell, GERALD L. "Mandell, Douglas, and Bennett's." Principles and practice of infectious diseases 7 (1995) Accessed on October 12,2016</ref><ref name=harrison>lymphanitis "Dennis Kasper, Anthony Fauci, Stephen Hauser, Dan Longo, J. Larry Jameson, Joseph Loscalzo"Harrison's Principles of Internal Medicine, 19e Accessed on October 12,2016</ref><ref name="pmid27271418">{{cite journal| author=Füeßl HS| title=[Emergency checklist: Acute lymphangitis]. | journal=MMW Fortschr Med | year= 2016 | volume= 158 | issue= 11 | pages= 65 | pmid=27271418 | doi=10.1007/s15006-016-8384-9 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27271418  }} </ref><ref name="pmid8480962">{{cite journal| author=Kostman JR, DiNubile MJ| title=Nodular lymphangitis: a distinctive but often unrecognized syndrome. | journal=Ann Intern Med | year= 1993 | volume= 118 | issue= 11 | pages= 883-8 | pmid=8480962 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8480962  }} </ref><ref name="pmid18317034">{{cite journal| author=Schubach A, Barros MB, Wanke B| title=Epidemic sporotrichosis. | journal=Curr Opin Infect Dis | year= 2008 | volume= 21 | issue= 2 | pages= 129-33 | pmid=18317034 | doi=10.1097/QCO.0b013e3282f44c52 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18317034  }} </ref><ref name="pmid27051706">{{cite journal| author=Chung E, Pulitzer MP, Papadopoulos EB, Papanicolaou GA, Babady NE, Marchetti MA| title=Lymphangitic papules caused by Nocardia takedensis. | journal=JAAD Case Rep | year= 2015 | volume= 1 | issue= 3 | pages= 126-8 | pmid=27051706 | doi=10.1016/j.jdcr.2015.03.001 | pmc=4808715 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27051706  }} </ref><ref name="pmid11472559">{{cite journal| author=Taylor MJ, Cross HF, Ford L, Makunde WH, Prasad GB, Bilo K| title=Wolbachia bacteria in filarial immunity and disease. | journal=Parasite Immunol | year= 2001 | volume= 23 | issue= 7 | pages= 401-9 | pmid=11472559 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11472559  }} </ref><ref name="pmid20739055">{{cite journal| author=Taylor MJ, Hoerauf A, Bockarie M| title=Lymphatic filariasis and onchocerciasis. | journal=Lancet | year= 2010 | volume= 376 | issue= 9747 | pages= 1175-85 | pmid=20739055 | doi=10.1016/S0140-6736(10)60586-7 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20739055  }} </ref>
Lymphangitis being a manifestation of wide concurrently occurring  spectrum of manifestations or pathologies.The history and symptoms varies from etiology to etiology.  
 
Specific history and symptoms for individual infections are discussed in detail separately.
==History and Symptoms==
==History and Symptoms==
*Clinical manifestation of lymphangitis are variable, depending on the etiology. History and symptoms based on the classification as follows:
Lymphangitis being a manifestation of wide concurrently occurring  spectrum of manifestations or pathologies.The history and symptoms varies from etiology to etiology. Commonly associated history and symptoms with different forms of etiology include:.<ref name="harrison">lymphanitis "Dennis Kasper, Anthony Fauci, Stephen Hauser, Dan Longo, J. Larry Jameson, Joseph Loscalzo"Harrison's Principles of Internal Medicine, 19e Accessed on October 12,2016</ref><ref name="pmid27271418">{{cite journal| author=Füeßl HS| title=[Emergency checklist: Acute lymphangitis]. | journal=MMW Fortschr Med | year= 2016 | volume= 158 | issue= 11 | pages= 65 | pmid=27271418 | doi=10.1007/s15006-016-8384-9 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27271418  }} </ref><ref name="pmid8480962">{{cite journal| author=Kostman JR, DiNubile MJ| title=Nodular lymphangitis: a distinctive but often unrecognized syndrome. | journal=Ann Intern Med | year= 1993 | volume= 118 | issue= 11 | pages= 883-8 | pmid=8480962 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8480962  }} </ref><ref name="pmid18317034">{{cite journal| author=Schubach A, Barros MB, Wanke B| title=Epidemic sporotrichosis. | journal=Curr Opin Infect Dis | year= 2008 | volume= 21 | issue= 2 | pages= 129-33 | pmid=18317034 | doi=10.1097/QCO.0b013e3282f44c52 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18317034  }} </ref><ref name="pmid27051706">{{cite journal| author=Chung E, Pulitzer MP, Papadopoulos EB, Papanicolaou GA, Babady NE, Marchetti MA| title=Lymphangitic papules caused by Nocardia takedensis. | journal=JAAD Case Rep | year= 2015 | volume= 1 | issue= 3 | pages= 126-8 | pmid=27051706 | doi=10.1016/j.jdcr.2015.03.001 | pmc=4808715 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27051706  }} </ref><ref name="pmid11472559">{{cite journal| author=Taylor MJ, Cross HF, Ford L, Makunde WH, Prasad GB, Bilo K| title=Wolbachia bacteria in filarial immunity and disease. | journal=Parasite Immunol | year= 2001 | volume= 23 | issue= 7 | pages= 401-9 | pmid=11472559 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11472559  }} </ref><ref name="pmid20739055">{{cite journal| author=Taylor MJ, Hoerauf A, Bockarie M| title=Lymphatic filariasis and onchocerciasis. | journal=Lancet | year= 2010 | volume= 376 | issue= 9747 | pages= 1175-85 | pmid=20739055 | doi=10.1016/S0140-6736(10)60586-7 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20739055  }} </ref>
 
===Lymphangitis due to infectious etiology===
===Lymphangitis due to infectious etiology===
====Acute lymphangitis====
====Acute lymphangitis====
=====Local manifestations=====
=====Local manifestations of acute lymphangitis include:<ref name="harrison" /><ref name="pmid27271418" /><ref name="pmid27051706" /><ref name="lymphangitis">lymphanitis Mandell, GERALD L. "Mandell, Douglas, and Bennett's." Principles and practice of infectious diseases 7 (1995) Accessed on October 12,2016</ref>=====
*Commonly effects the extremities  
*Commonly effects the extremities  
*Pain(throbbing in nature)
*Pain(throbbing in nature)
Line 16: Line 19:
*Swelling of the region  
*Swelling of the region  
*Red streaks from the infected area to the regional lymph node
*Red streaks from the infected area to the regional lymph node
====Systemic manifestations====
====Systemic manifestations of acute lymphangitis include:<ref name="harrison" /><ref name="pmid27271418" /><ref name="pmid27051706" /><ref name="lymphangitis" />====
*[[Chills]]
*[[Chills]]
*[[Headache]]
*[[Headache]]
Line 23: Line 26:
*Enlarged and tender lymph nodes
*Enlarged and tender lymph nodes
*[[Muscle aches]]   
*[[Muscle aches]]   
====Chronic Granulomatous Lymphangitis====
====Common symptoms of chronic granulomatous lymphangitis include:<ref name="harrison" /><ref name="pmid8480962" /><ref name="pmid18317034" /><ref name="lymphangitis" />====
*Commonly effects the extremities
*Commonly effects the extremities
*Painless or painful subcutaneous nodule at the site of incoulation
*Painless or painful subcutaneous nodule at the site of incoulation
*Nodules may subsequently ulcerate at site on inoculation, as seen in case of Sporothrix schenckii
*Nodules may subsequently ulcerate at site on inoculation, as seen in case of Sporothrix schenckii
*Slowly, multiple subcutaneous nodules appear and extend proximally along the course of lymphatics
*Slowly, multiple subcutaneous nodules appear and extend proximally along the course of lymphatics
====Filarial lymphangitis====
For history and symtoms of filarial lymphangitis please [http://www.wikidoc.org/index.php/Filariasis_history_and_symptoms click here]
*Acute filarial lymphangitis(Acute adenolymphangitis) charcterize by:
 
**High fever
===Lymphangitis due to non-infectious etiology===
**Lymphangitis, extending peripherally from the lymph node
** Recurrent episodes of headache, backache, epididymitis, and orchitis
===Lymphangitis due to infectious etiology===
====Lymphangitis carcinomatosa====
====Lymphangitis carcinomatosa====
*Commonly involves the lung<ref name="pmid8930034">{{cite journal| author=Bruce DM, Heys SD, Eremin O| title=Lymphangitis carcinomatosa: a literature review. | journal=J R Coll Surg Edinb | year= 1996 | volume= 41 | issue= 1 | pages= 7-13 | pmid=8930034 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8930034  }} </ref>
*Commonly involves the lung<ref name="pmid8930034">{{cite journal| author=Bruce DM, Heys SD, Eremin O| title=Lymphangitis carcinomatosa: a literature review. | journal=J R Coll Surg Edinb | year= 1996 | volume= 41 | issue= 1 | pages= 7-13 | pmid=8930034 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8930034  }} </ref>

Revision as of 20:58, 29 December 2016

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Vendhan Ramanujam M.B.B.S [2]Vishal Devarkonda, M.B.B.S[3]

Overview

Lymphangitis being a manifestation of wide concurrently occurring spectrum of manifestations or pathologies.The history and symptoms varies from etiology to etiology.

Specific history and symptoms for individual infections are discussed in detail separately.

History and Symptoms

Lymphangitis being a manifestation of wide concurrently occurring spectrum of manifestations or pathologies.The history and symptoms varies from etiology to etiology. Commonly associated history and symptoms with different forms of etiology include:.[1][2][3][4][5][6][7]

Lymphangitis due to infectious etiology

Acute lymphangitis

Local manifestations of acute lymphangitis include:[1][2][5][8]
  • Commonly effects the extremities
  • Pain(throbbing in nature)
  • Redness
  • Swelling of the region
  • Red streaks from the infected area to the regional lymph node

Systemic manifestations of acute lymphangitis include:[1][2][5][8]

Common symptoms of chronic granulomatous lymphangitis include:[1][3][4][8]

  • Commonly effects the extremities
  • Painless or painful subcutaneous nodule at the site of incoulation
  • Nodules may subsequently ulcerate at site on inoculation, as seen in case of Sporothrix schenckii
  • Slowly, multiple subcutaneous nodules appear and extend proximally along the course of lymphatics

For history and symtoms of filarial lymphangitis please click here

Lymphangitis due to non-infectious etiology

Lymphangitis carcinomatosa

  • Commonly involves the lung[9]
    • Dyspnea(insidious in onset)
  • Non-productive cough
  • Chest pain
  • Cyanosis
  • Cachexia

Sclerosing lymphangitis

Patient with sclerosing lymphangitis present with:

  • Genital discomfort or pain in the genital area
  • Sudden onset of flesh colored red firm, cordlike lesion on penis

References

  1. ↑ 1.0 1.1 1.2 1.3 lymphanitis "Dennis Kasper, Anthony Fauci, Stephen Hauser, Dan Longo, J. Larry Jameson, Joseph Loscalzo"Harrison's Principles of Internal Medicine, 19e Accessed on October 12,2016
  2. ↑ 2.0 2.1 2.2 Füeßl HS (2016). "[Emergency checklist: Acute lymphangitis]". MMW Fortschr Med. 158 (11): 65. doi:10.1007/s15006-016-8384-9. PMID 27271418.
  3. ↑ 3.0 3.1 Kostman JR, DiNubile MJ (1993). "Nodular lymphangitis: a distinctive but often unrecognized syndrome". Ann Intern Med. 118 (11): 883–8. PMID 8480962.
  4. ↑ 4.0 4.1 Schubach A, Barros MB, Wanke B (2008). "Epidemic sporotrichosis". Curr Opin Infect Dis. 21 (2): 129–33. doi:10.1097/QCO.0b013e3282f44c52. PMID 18317034.
  5. ↑ 5.0 5.1 5.2 Chung E, Pulitzer MP, Papadopoulos EB, Papanicolaou GA, Babady NE, Marchetti MA (2015). "Lymphangitic papules caused by Nocardia takedensis". JAAD Case Rep. 1 (3): 126–8. doi:10.1016/j.jdcr.2015.03.001. PMC 4808715. PMID 27051706.
  6. ↑ Taylor MJ, Cross HF, Ford L, Makunde WH, Prasad GB, Bilo K (2001). "Wolbachia bacteria in filarial immunity and disease". Parasite Immunol. 23 (7): 401–9. PMID 11472559.
  7. ↑ Taylor MJ, Hoerauf A, Bockarie M (2010). "Lymphatic filariasis and onchocerciasis". Lancet. 376 (9747): 1175–85. doi:10.1016/S0140-6736(10)60586-7. PMID 20739055.
  8. ↑ 8.0 8.1 8.2 lymphanitis Mandell, GERALD L. "Mandell, Douglas, and Bennett's." Principles and practice of infectious diseases 7 (1995) Accessed on October 12,2016
  9. ↑ Bruce DM, Heys SD, Eremin O (1996). "Lymphangitis carcinomatosa: a literature review". J R Coll Surg Edinb. 41 (1): 7–13. PMID 8930034.

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