Hemophilia A differential diagnosis: Difference between revisions
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==Overview== | ==Overview== | ||
Hemophilia A must be differentiated from other diseases that cause abnormal or excessive bleeding <ref> Konkle BA, Josephson NC, Nakaya Fletcher S. Hemophilia A. 2000 Sep 21 [Updated 2014 Jun 5]. In: Pagon RA, Adam MP, Ardinger HH, et al., editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2016. Available from: http://www-ncbi-nlm-nih-gov.laneproxy.stanford.edu/books/NBK1404/ </ref> | [[Hemophilia A]] must be differentiated from other diseases that cause abnormal or excessive bleeding <ref> Konkle BA, Josephson NC, Nakaya Fletcher S. Hemophilia A. 2000 Sep 21 [Updated 2014 Jun 5]. In: Pagon RA, Adam MP, Ardinger HH, et al., editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2016. Available from: http://www-ncbi-nlm-nih-gov.laneproxy.stanford.edu/books/NBK1404/ </ref> | ||
==Differentiating Hemophilia A from other Diseases== | ==Differentiating Hemophilia A from other Diseases== | ||
The most important [[differential diagnosis]] is that of [[hemophilia B]] (also known as Christmas disease) or [[von Willebrand disease]]. The former is usually considered if factor VIII levels are normal in a person with a haemophilia phenotype. The latter is excluded on routine testing for that condition. | The most important [[differential diagnosis]] is that of [[hemophilia B]] (also known as Christmas disease) or [[von Willebrand disease]]. The former is usually considered if [[factor VIII]] levels are normal in a person with a haemophilia phenotype. The latter is excluded on routine testing for that condition. | ||
==Differential Diagnosis== | ==Differential Diagnosis== | ||
Other diseases which should be considered in the differential include: | Other diseases which should be considered in the differential include: | ||
*Warfarin toxicity | *[[Warfarin]] toxicity | ||
*Liver disease | *[[Liver disease]] | ||
*Vitamin K deficiency | *[[Vitamin K]] deficiency | ||
==References== | ==References== | ||
Revision as of 08:33, 27 March 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Fahd Yunus, M.D. [2]
Overview
Hemophilia A must be differentiated from other diseases that cause abnormal or excessive bleeding [1]
Differentiating Hemophilia A from other Diseases
The most important differential diagnosis is that of hemophilia B (also known as Christmas disease) or von Willebrand disease. The former is usually considered if factor VIII levels are normal in a person with a haemophilia phenotype. The latter is excluded on routine testing for that condition.
Differential Diagnosis
Other diseases which should be considered in the differential include:
- Warfarin toxicity
- Liver disease
- Vitamin K deficiency
References
- ↑ Konkle BA, Josephson NC, Nakaya Fletcher S. Hemophilia A. 2000 Sep 21 [Updated 2014 Jun 5]. In: Pagon RA, Adam MP, Ardinger HH, et al., editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2016. Available from: http://www-ncbi-nlm-nih-gov.laneproxy.stanford.edu/books/NBK1404/