Ureaplasma urealyticum medical therapy: Difference between revisions
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==Overview== | ==Overview== | ||
==Medical Therapy== | ==Medical Therapy== | ||
Antibiotics are the mainstay of treatment for Ureaplasma infection | Antibiotics are the mainstay of treatment for Ureaplasma infection. Antibiotic susceptibility testing should be done to avoid treatment failure because of the geographical differences in antibiotic resistance. | ||
'''Recommended antibiotics'''<ref name="pmid23192735">{{cite journal| author=De Francesco MA, Caracciolo S, Bonfanti C, Manca N| title=Incidence and antibiotic susceptibility of Mycoplasma hominis and Ureaplasma urealyticum isolated in Brescia, Italy, over 7 years. | journal=J Infect Chemother | year= 2013 | volume= 19 | issue= 4 | pages= 621-7 | pmid=23192735 | doi=10.1007/s10156-012-0527-z | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23192735 }} </ref><ref name="pmid26518581"/><ref name="pmid27401661">{{cite journal| author=Lee MY, Kim MH, Lee WI, Kang SY, Jeon YL| title=Prevalence and Antibiotic Susceptibility of Mycoplasma hominis and Ureaplasma urealyticum in Pregnant Women. | journal=Yonsei Med J | year= 2016 | volume= 57 | issue= 5 | pages= 1271-5 | pmid=27401661 | doi=10.3349/ymj.2016.57.5.1271 | pmc=4960396 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27401661 }} </ref> | |||
* [[Doxycycline]] | |||
# This is the drug of first choice. | |||
# It is the most active [[tetracycline]] for [[Mycoplasma]] and Ureaplasma infection. | |||
# It should be avoided in pregnant women and young children. | |||
* [[Macrolides]] | |||
# [[Josamycin]] and [[clarithromycin]] are the most effective macrolides against Ureaplasma infection. | |||
# [[Josamycin]] is often recommended for neonates and pregnant women, especially when mixed infection is present. | |||
# [[Pristinamycin]] can be used as an alternative to [[Josamycin]] in pregnant women. | |||
# [[Erythromycin]] has a low efficacy against ''Ureaplasma urealyticum''. | |||
* [[Fluoroquinolones]]: They have a low efficacy against urogenital [[Mycoplasma]] and Ureaplasma infection. | |||
* [[Clindamycin]]: This has also been demonstrated to have a low efficacy against Ureaplasma species. | |||
==References== | ==References== | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Fatimo Biobaku M.B.B.S [2]
Overview
Medical Therapy
Antibiotics are the mainstay of treatment for Ureaplasma infection. Antibiotic susceptibility testing should be done to avoid treatment failure because of the geographical differences in antibiotic resistance.
Recommended antibiotics[1][2][3]
- This is the drug of first choice.
- It is the most active tetracycline for Mycoplasma and Ureaplasma infection.
- It should be avoided in pregnant women and young children.
- Josamycin and clarithromycin are the most effective macrolides against Ureaplasma infection.
- Josamycin is often recommended for neonates and pregnant women, especially when mixed infection is present.
- Pristinamycin can be used as an alternative to Josamycin in pregnant women.
- Erythromycin has a low efficacy against Ureaplasma urealyticum.
- Fluoroquinolones: They have a low efficacy against urogenital Mycoplasma and Ureaplasma infection.
- Clindamycin: This has also been demonstrated to have a low efficacy against Ureaplasma species.
References
- ↑ De Francesco MA, Caracciolo S, Bonfanti C, Manca N (2013). "Incidence and antibiotic susceptibility of Mycoplasma hominis and Ureaplasma urealyticum isolated in Brescia, Italy, over 7 years". J Infect Chemother. 19 (4): 621–7. doi:10.1007/s10156-012-0527-z. PMID 23192735.
- ↑ Invalid
<ref>tag; no text was provided for refs namedpmid26518581 - ↑ Lee MY, Kim MH, Lee WI, Kang SY, Jeon YL (2016). "Prevalence and Antibiotic Susceptibility of Mycoplasma hominis and Ureaplasma urealyticum in Pregnant Women". Yonsei Med J. 57 (5): 1271–5. doi:10.3349/ymj.2016.57.5.1271. PMC 4960396. PMID 27401661.