Diphyllobothriasis medical therapy: Difference between revisions
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==Medical Therapy== | ==Medical Therapy== | ||
===Praziquantel=== | ===Praziquantel=== | ||
Oral [[praziquantel]] is available for human use in the United States. | Oral [[praziquantel]] is available for human use in the United States. Praziquantel increases the permeability of the cell membrane towards calcium ions. This induces contraction of the parasites, resulting in paralysis in the contracted state. | ||
===Niclosamide=== | ===Niclosamide=== | ||
Revision as of 19:46, 28 June 2017
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Diphyllobothriasis Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Diphyllobothriasis medical therapy On the Web |
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American Roentgen Ray Society Images of Diphyllobothriasis medical therapy |
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Risk calculators and risk factors for Diphyllobothriasis medical therapy |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Kalsang Dolma, M.B.B.S.[2] Furqan M M. M.B.B.S[3]
Overview
Medical Therapy
Praziquantel
Oral praziquantel is available for human use in the United States. Praziquantel increases the permeability of the cell membrane towards calcium ions. This induces contraction of the parasites, resulting in paralysis in the contracted state.
Niclosamide
Niclosamide is NOT available for human use in the United States.
Shown below is a table summarizing the preferred and alternative empiric treatment for Diphyllobothriasis[1]
| Pathogens | Preferred Treatment | Duration of Treatment | Alternative Treatment |
| Diphyllobothrium latum | Praziquantel*
Adults, 5-10 mg/kg orally in a single-dose therapy; the dosage for children is the same. |
Single dose | Niclosamide
Adult 2 gm orally once; children, 50 mg/kg (max 2 gm) orally once. |
- Not FDA-approved for this indication.*
- (Note: praziquantel should be taken with liquids during a meal.)