Fever of unknown origin diagnostic criteria: Difference between revisions
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| style="vertical-align: middle; padding: 5px;" align=center | [[File:Siren.gif|30px|link=Fever of unknown origin resident survival guide]] | | style="vertical-align: middle; padding: 5px;" align="center" |[[File:Siren.gif|30px|link=Fever of unknown origin resident survival guide]] | ||
| style="vertical-align: middle; padding: 5px;" align=center | [[Fever of unknown origin resident survival guide|'''Resident'''<br>'''Survival'''<br>'''Guide''']] | | style="vertical-align: middle; padding: 5px;" align="center" |[[Fever of unknown origin resident survival guide|'''Resident'''<br>'''Survival'''<br>'''Guide''']] | ||
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==Diagnostic Criteria== | ==Diagnostic Criteria== | ||
According Petersdorf and Beeson diagnostic criteria proposed in 1991:<ref name="pmid32462043">{{cite journal| author=Wright WF, Auwaerter PG| title=Fever and Fever of Unknown Origin: Review, Recent Advances, and Lingering Dogma. | journal=Open Forum Infect Dis | year= 2020 | volume= 7 | issue= 5 | pages= ofaa132 | pmid=32462043 | doi=10.1093/ofid/ofaa132 | pmc=7237822 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=32462043 }}</ref><ref name="pmid22475734">{{cite journal| author=Hayakawa K, Ramasamy B, Chandrasekar PH| title=Fever of unknown origin: an evidence-based review. | journal=Am J Med Sci | year= 2012 | volume= 344 | issue= 4 | pages= 307-16 | pmid=22475734 | doi=10.1097/MAJ.0b013e31824ae504 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22475734 }}</ref> | |||
* Fever | * Fever above 38.3° C (100.9° F) | ||
* | * For more than three weeks | ||
* No diagnosis after work up for at least three visits in outdoor or three days of stay in hospital | |||
==Classification== | ==Classification== | ||
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==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
[[Category:Ailments of unknown etiology]] | [[Category:Ailments of unknown etiology]] |
Revision as of 21:41, 23 January 2021
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Synonyms and keywords: febris continua e causa ignota; febris e causa ignota; febris E.C.I.; fever/pyrexia of obscured/undetermined/uncertain/unidentifiable/unknown focus/origin/source; fever/pyrexia without a focus/origin/source; FUO; PUO
Diagnostic Criteria
According Petersdorf and Beeson diagnostic criteria proposed in 1991:[1][2]
- Fever above 38.3° C (100.9° F)
- For more than three weeks
- No diagnosis after work up for at least three visits in outdoor or three days of stay in hospital
Classification
In 1991, Durack and Street proposed a revised definition in which cases of FUO are categorized into four subclasses: classic FUO, nosocomial (health care-associated) FUO, neutropenic (immune-deficient) FUO, and HIV-related FUO.[3]
Classic FUO
Fever (>38.3° C or >100.9° F) for >3 weeks with no identified cause after 3 days of hospital evaluation or ≥3 outpatient visits
Nosocomial (health care-associated) FUO
Fever (>38.3° C or >100.9° F) in hospitalized patients receiving acute care and with no infection present or incubating on admission if the diagnosis remains uncertain after 3 days of appropriate evaluation
Neutropenic (immune-deficient) FUO
Fever (>38.3° C or >100.9° F) in patients with neutropenia (absolute neutrophil count ≤500 per mm3) or immunodeficiency if the diagnosis remains uncertain after 3 days of appropriate evaluation, including negative cultures after 48 hours
Fever (>38.3° C or >100.9° F) for >3 weeks in outpatients with confirmed HIV infection or >3 days in inpatients with confirmed HIV infection if the diagnosis remains uncertain after appropriate evaluation
References
- ↑ Wright WF, Auwaerter PG (2020). "Fever and Fever of Unknown Origin: Review, Recent Advances, and Lingering Dogma". Open Forum Infect Dis. 7 (5): ofaa132. doi:10.1093/ofid/ofaa132. PMC 7237822 Check
|pmc=
value (help). PMID 32462043 Check|pmid=
value (help). - ↑ Hayakawa K, Ramasamy B, Chandrasekar PH (2012). "Fever of unknown origin: an evidence-based review". Am J Med Sci. 344 (4): 307–16. doi:10.1097/MAJ.0b013e31824ae504. PMID 22475734.
- ↑ Durack, D. T.; Street, A. C. (1991). "Fever of unknown origin--reexamined and redefined". Current Clinical Topics in Infectious Diseases. 11: 35–51. ISSN 0195-3842. PMID 1651090.