Human respiratory syncytial virus historical perspective: Difference between revisions
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{{Human respiratory syncytial virus}} | {{Human respiratory syncytial virus}} | ||
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==Overview== | |||
==Historical Perspective== | |||
* RSV was first identified in 1956. The virus was isolated in chimpanzees with respiratory tract infections and was therefore referred to as chimpanzee coryza agent. (https://journals.sagepub.com/doi/abs/10.3181/00379727-92-22538) | |||
* In 1957, two similar viruses were isolated in infants with respiratory illnesses, which demonstrated to be indistinguishable from chimpanzee coryza agent. The virus was confirmed in humans and to be associated with respiratory illnesses in children. (https://academic.oup.com/aje/article-abstract/66/3/281/160550?redirectedFrom=fulltext&login=false) | |||
https://www.nejm.org/doi/10.1056/NEJM196009152631101 | |||
* The virus was renamed in subsequent years to ”respiratory syncytial virus” given the characteristic cytopathic effect on tissue culture cells by which the infected epithelial cells clump together to form large cell-like structure known as syncytia . (https://pubmed.ncbi.nlm.nih.gov/13692354/) (https://www.sciencedirect.com/topics/immunology-and-microbiology/human-respiratory-syncytial-virus) (https://www.nejm.org/doi/full/10.1056/NEJM199107043250110) | |||
==References== | ==References== | ||
Revision as of 15:43, 3 December 2022
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Human respiratory syncytial virus Microchapters |
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Differentiating Human Respiratory Syncytial Virus from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Bassel Almarie M.D.[2]
Overview
Historical Perspective
- RSV was first identified in 1956. The virus was isolated in chimpanzees with respiratory tract infections and was therefore referred to as chimpanzee coryza agent. (https://journals.sagepub.com/doi/abs/10.3181/00379727-92-22538)
- In 1957, two similar viruses were isolated in infants with respiratory illnesses, which demonstrated to be indistinguishable from chimpanzee coryza agent. The virus was confirmed in humans and to be associated with respiratory illnesses in children. (https://academic.oup.com/aje/article-abstract/66/3/281/160550?redirectedFrom=fulltext&login=false)
https://www.nejm.org/doi/10.1056/NEJM196009152631101
- The virus was renamed in subsequent years to ”respiratory syncytial virus” given the characteristic cytopathic effect on tissue culture cells by which the infected epithelial cells clump together to form large cell-like structure known as syncytia . (https://pubmed.ncbi.nlm.nih.gov/13692354/) (https://www.sciencedirect.com/topics/immunology-and-microbiology/human-respiratory-syncytial-virus) (https://www.nejm.org/doi/full/10.1056/NEJM199107043250110)