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*1308-1340: Postpartum thyroid dysfunction was first observed in pictures of Madonna Enthroned by Duccio and Lorenzetti holding child in lap with Goiter which later proved by Dr Glinoer D 1997 due to iodine deficiency leading to postpartum thyroid dysfunction.<ref name="LazzeriCastello2016">{{cite journal|last1=Lazzeri|first1=Davide|last2=Castello|first2=ManuelFrancisco|last3=Lippi|first3=Donatella|last4=Weisz|first4=GeorgeM|title=Goiter in portraits of Judith the Jewish heroine|journal=Indian Journal of Endocrinology and Metabolism|volume=20|issue=1|year=2016|pages=119|issn=2230-8210|doi=10.4103/2230-8210.172266}}</ref>
*1308-1340: Postpartum thyroid dysfunction was first observed in pictures of Madonna Enthroned by Duccio and Lorenzetti holding child in lap with Goiter which later proved by Dr Glinoer D 1997 due to iodine deficiency leading to postpartum thyroid dysfunction.<ref name="LazzeriCastello2016">{{cite journal|last1=Lazzeri|first1=Davide|last2=Castello|first2=ManuelFrancisco|last3=Lippi|first3=Donatella|last4=Weisz|first4=GeorgeM|title=Goiter in portraits of Judith the Jewish heroine|journal=Indian Journal of Endocrinology and Metabolism|volume=20|issue=1|year=2016|pages=119|issn=2230-8210|doi=10.4103/2230-8210.172266}}</ref>


*1786: Parry CH who observed signs of hyperthyroidism in postpartum women and paper published in 1825.
*1786: Parry CH , British physician, who observed signs of hyperthyroidism in postpartum women which he described in his paper published in the posthumous publication.
*1868: Dr. Armand Trousseau, observed signs of hypothyroidisum in postpartum patients who got relief from symptoms on end of postpartum and establishment of menstrual cycle or conception but he could not connect relation of hypothyroidism to postpartum. His literature says "goitre occurring in pregnant women is apparently due to pregnancy, while that of exophthalmos is seemingly cured by pregnancy"
*1868: Dr. Armand Trousseau, observed signs of hypothyroidisum in postpartum patients who got relief from symptoms on end of postpartum and establishment of menstrual cycle or conception but he could not connect relation of hypothyroidism to postpartum. His literature says "goitre occurring in pregnant women is apparently due to pregnancy, while that of exophthalmos is seemingly cured by pregnancy"
*1988: Sir H. Bryan Donkin associated symptoms of hypothyroidism related to pregnancy which got better after the end of postpartum period.
*1988: Sir H. Bryan Donkin associated symptoms of hypothyroidism related to pregnancy which got better after the end of postpartum period.

Revision as of 02:07, 28 September 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

Postpartum thyroid dysfunction was first discovered by Dr. W.E.H. Robertson, a British physician, who diagnosed postpartum patients with symptoms of hypothyroidism after pregnancy and their improvement on treatment with thyroid extracts in 1946.

Historical Perspective

Discovery

  • 1946: Postpartum thyroid dysfunction was first discovered by Dr. W.E.H. Robertson, a British physician, who diagnosed postpartum patients with symptoms of hypothyroidism after pregnancy and their improvement on treatment with thyroid extracts.[1]
  • 98-138 AD: PPT was first observed by Soranus, Roman gynecologist, as neck swelling after birth of baby which he published in book Gynaecia.[2]
  • 1308-1340: Postpartum thyroid dysfunction was first observed in pictures of Madonna Enthroned by Duccio and Lorenzetti holding child in lap with Goiter which later proved by Dr Glinoer D 1997 due to iodine deficiency leading to postpartum thyroid dysfunction.[3]
  • 1786: Parry CH , British physician, who observed signs of hyperthyroidism in postpartum women which he described in his paper published in the posthumous publication.
  • 1868: Dr. Armand Trousseau, observed signs of hypothyroidisum in postpartum patients who got relief from symptoms on end of postpartum and establishment of menstrual cycle or conception but he could not connect relation of hypothyroidism to postpartum. His literature says "goitre occurring in pregnant women is apparently due to pregnancy, while that of exophthalmos is seemingly cured by pregnancy"
  • 1988: Sir H. Bryan Donkin associated symptoms of hypothyroidism related to pregnancy which got better after the end of postpartum period.
  • 1953: Danowski and colleagues, compared levels of serum protein-bound iodine (PBI) during and after pregnancy and postpartum period, and found them low in postpartum and improving after postpartum period.
  • 1961: Parker and Beierwaltes found antithyroid antibodies decreasing in pregnancy and increasing in postpartum period.
  • In 1982, Amino and colleagues were the first to discover the association between postpartum period and the development of transient hyperthyroidism and/or hypothyroidism with prevalence of 5.5% of 505 Japanese women.

Landmark Events in the Development of Treatment Strategies

  • In 1976, Anti-thyroid microsomal antibodies were observed correlation to postpartum thyroisits by Nobuyuki Amino.[4]

Impact on Cultural History

Famous Cases

References

  1. Smallridge, Robert C. (1999). "Postpartum Thyroid Diseases Through The Ages: A Historical View". Thyroid. 9 (7): 671–673. doi:10.1089/thy.1999.9.671. ISSN 1050-7256.
  2. Smallridge, Robert C. (2014). "Clark T. Sawin Historical Vignette: What Do Criminology, Harry Houdini, and King George V Have in Common with Postpartum Thyroid Dysfunction?". Thyroid. 24 (12): 1752–1758. doi:10.1089/thy.2014.0165. ISSN 1050-7256.
  3. Lazzeri, Davide; Castello, ManuelFrancisco; Lippi, Donatella; Weisz, GeorgeM (2016). "Goiter in portraits of Judith the Jewish heroine". Indian Journal of Endocrinology and Metabolism. 20 (1): 119. doi:10.4103/2230-8210.172266. ISSN 2230-8210.
  4. Amino, Nobuyuki; Miyai, Kiyoshi; Onishi, Toshio; Hashimoto, Takuma; Arai, Kayoko; Ishibashi, Kaichiro; Kumahara, Yuichi (1976). "Transient Hypothyroidism After Delivery in Autoimmune Thyroiditis". The Journal of Clinical Endocrinology & Metabolism. 42 (2): 296–301. doi:10.1210/jcem-42-2-296. ISSN 0021-972X.

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