Postpartum thyroiditis laboratory findings: Difference between revisions
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{| class="wikitable" | {| class="wikitable" | ||
!lab values | !lab values | ||
!Hyperthyroid phase | ![[Hyperthyroid]] phase | ||
!Hypothyroid phase | ![[Hypothyroid]] phase | ||
|- | |- | ||
|Serum TSH | |Serum [[TSH]] | ||
|less than 3.5 micrograms/dl | |less than 3.5 micrograms/dl | ||
|more than 3.5 micrograms/dl | |more than 3.5 micrograms/dl | ||
|- | |- | ||
|Serum free T4 | |Serum free [[T4]] | ||
|elevated but may be normal | |elevated but may be normal | ||
|decreased | |decreased | ||
|- | |- | ||
|Serum free T3 | |Serum free [[T3]] | ||
|elevated or normal | |elevated or normal | ||
|decreased | |decreased | ||
|- | |- | ||
|Serum Anti-TPO anitbodies | |Serum Anti-[[TPO|Thyroid peroxidase]] anitbodies | ||
|postive | |postive | ||
|postive | |postive | ||
|- | |- | ||
|Serum TSH-receptor abs | |Serum [[TSH]]-receptor abs | ||
|negative or positive with coexisting [[Grave's disease]] | |negative or positive with coexisting [[Grave's disease]] | ||
|negative | |negative | ||
|- | |- | ||
|Serum ESR | |Serum [[ESR]] | ||
|normal | |normal | ||
|normal | |normal | ||
|- | |- | ||
|Serum thyroglobulin Tg | |Serum [[thyroglobulin]] Tg | ||
|elevated in early phase of destruction of follicles | |elevated in early phase of destruction of follicles | ||
|elevated in early phase of destruction of follicles | |elevated in early phase of destruction of follicles | ||
|- | |- | ||
|Radio-iodine uptake | |[[Radio-iodine]] uptake | ||
|decreased | |decreased | ||
|decreased | |decreased | ||
Revision as of 11:48, 19 October 2017
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Postpartum thyroiditis Microchapters |
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Postpartum thyroiditis laboratory findings On the Web |
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Risk calculators and risk factors for Postpartum thyroiditis laboratory findings |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sunny Kumar MD [2]
Overview
Laboratory findings consistent with the diagnosis of PPT depend on the phase of disease and include screening of serum TSH, serum free T4, serum free T3, serum Anti-TPO anitbodies, serum TSH-receptor abs, serum ESR, serum thyroglobulin Tg and radio-iodine uptake. Some patients with PPT may have elevated concentration of Serum Anti-TPO abs, which is usually suggestive of future hypothyroidism.
Laboratory Findings
- Some patients with PPT may have elevated concentration of Serum Anti-TPO abs, which is usually suggestive of future hypothyroidism.
- Laboratory findings consistent with the diagnosis of PPT depend on the phase of disease and include:
| lab values | Hyperthyroid phase | Hypothyroid phase |
|---|---|---|
| Serum TSH | less than 3.5 micrograms/dl | more than 3.5 micrograms/dl |
| Serum free T4 | elevated but may be normal | decreased |
| Serum free T3 | elevated or normal | decreased |
| Serum Anti-Thyroid peroxidase anitbodies | postive | postive |
| Serum TSH-receptor abs | negative or positive with coexisting Grave's disease | negative |
| Serum ESR | normal | normal |
| Serum thyroglobulin Tg | elevated in early phase of destruction of follicles | elevated in early phase of destruction of follicles |
| Radio-iodine uptake | decreased | decreased |
References
- ↑ Muller AF, Drexhage HA, Berghout A (2001). "Postpartum thyroiditis and autoimmune thyroiditis in women of childbearing age: recent insights and consequences for antenatal and postnatal care". Endocr Rev. 22 (5): 605–30. doi:10.1210/edrv.22.5.0441. PMID 11588143.
- ↑ Argatska AB, Nonchev BI (2014). "Postpartum thyroiditis". Folia Med (Plovdiv). 56 (3): 145–51. PMID 25434070.
- ↑ Stagnaro-Green A (2012). "Approach to the patient with postpartum thyroiditis". J Clin Endocrinol Metab. 97 (2): 334–42. doi:10.1210/jc.2011-2576. PMID 22312089.