Wilson's disease natural history, complications and prognosis: Difference between revisions
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Created page with "__NOTOC__ {{Wilson's disease}} {{CMG}}; {{AE}} {{AEL}} ==Overview== ==Natural History, Complications, and Prognosis== ===Natural history=== ===Complications=== ===Prognos..." |
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===Natural history=== | ===Natural history=== | ||
* The symptoms of Wilson's disease usually develop between age of 5 and 35 years. However, the symptoms can be presented at any age onset. | |||
* If left untreated, Wilson's disease will lead to death. The copper accumulation in the liver and the brain will end up with cirrhosis and severe dystonia respectively. <ref name="pmid22340672">{{cite journal| author=European Association for Study of Liver| title=EASL Clinical Practice Guidelines: Wilson's disease. | journal=J Hepatol | year= 2012 | volume= 56 | issue= 3 | pages= 671-85 | pmid=22340672 | doi=10.1016/j.jhep.2011.11.007 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22340672 }}</ref> | |||
===Complications=== | ===Complications=== | ||
* Common complications of Wilson's disease include the following: | |||
** Hepatocellular carcinoma | |||
===Prognosis=== | ===Prognosis=== | ||
* Prognosis of Wilson's disease is usually excellent with proper treatment except in the severely advanced patients. | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
Revision as of 16:13, 17 December 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2]
Overview
Natural History, Complications, and Prognosis
Natural history
- The symptoms of Wilson's disease usually develop between age of 5 and 35 years. However, the symptoms can be presented at any age onset.
- If left untreated, Wilson's disease will lead to death. The copper accumulation in the liver and the brain will end up with cirrhosis and severe dystonia respectively. [1]
Complications
- Common complications of Wilson's disease include the following:
- Hepatocellular carcinoma
Prognosis
- Prognosis of Wilson's disease is usually excellent with proper treatment except in the severely advanced patients.
References
- ↑ European Association for Study of Liver (2012). "EASL Clinical Practice Guidelines: Wilson's disease". J Hepatol. 56 (3): 671–85. doi:10.1016/j.jhep.2011.11.007. PMID 22340672.