VIPoma surgery: Difference between revisions
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==Surgery== | ==Surgery== | ||
*Surgery should be considered after initial symptomatic management of VIPoma in operable cases. | *Surgery should be considered after initial symptomatic management of VIPoma in operable cases. | ||
*Complete surgical resection of tumor is the only curative treatment for VIPoma. The feasibility of surgery depends on the stage of VIPoma at diagnosis.<ref name="surgery">Pancreatic Neuroendocrine Tumors (Islet Cell Tumors). National Cancer Institute. http://www.cancer.gov/types/pancreatic/hp/pnet-treatment-pdq#section/_78. Accessed on October 21, 2015.</ref> | *Complete surgical resection of tumor is the only curative treatment for VIPoma. | ||
*The feasibility of surgery depends on the stage of VIPoma at diagnosis.<ref name="surgery">Pancreatic Neuroendocrine Tumors (Islet Cell Tumors). National Cancer Institute. http://www.cancer.gov/types/pancreatic/hp/pnet-treatment-pdq#section/_78. Accessed on October 21, 2015.</ref> | |||
*If the tumor cannot be removed completely, surgical debulking may have palliative effect for control of hormonal symptoms.<ref name="sp">Vinik A. Vasoactive Intestinal Peptide Tumor (VIPoma) [Updated 2013 Nov 28]. In: De Groot LJ, Beck-Peccoz P, Chrousos G, et al., editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000-. Available from: http://www.ncbi.nlm.nih.gov/books/NBK278960/</ref> | *If the tumor cannot be removed completely, surgical debulking may have palliative effect for control of hormonal symptoms.<ref name="sp">Vinik A. Vasoactive Intestinal Peptide Tumor (VIPoma) [Updated 2013 Nov 28]. In: De Groot LJ, Beck-Peccoz P, Chrousos G, et al., editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000-. Available from: http://www.ncbi.nlm.nih.gov/books/NBK278960/</ref> | ||
*In nonresectable liver metastases, | *In nonresectable liver metastases, hepatic [[Transcatheter arterial chemoembolization|TACE]] (transarterial chemoembolization) is emerging as a new non-emergency therapeutic modality highly successful for control of VIP-related symptoms.<ref name="pmid4981295">{{cite journal| author=Blaise A, Girardet JL| title=[Study of the magnetic properties of siderophilin]. | journal=C R Acad Sci Hebd Seances Acad Sci D | year= 1969 | volume= 269 | issue= 10 | pages= 966-8 | pmid=4981295 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=4981295 }}</ref> | ||
[[Image:Intra_operative.jpg|center|400px|thumb|Intraoperative aspect of liver lesions (arrows).]] | [[Image:Intra_operative.jpg|center|400px|thumb|Intraoperative aspect of liver lesions (arrows).]] | ||
Revision as of 20:26, 19 January 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Madhu Sigdel M.B.B.S.[2]Parminder Dhingra, M.D. [3]
Overview
Surgery is the mainstay of treatment for VIPoma. Surgery should be considered after initial symptomatic management of VIPoma in operable cases. Complete surgical resection of tumor is the only curative treatment for VIPoma. If the tumor cannot be removed completely, surgical debulking may have palliative effect for control of hormonal symptoms.
Surgery
- Surgery should be considered after initial symptomatic management of VIPoma in operable cases.
- Complete surgical resection of tumor is the only curative treatment for VIPoma.
- The feasibility of surgery depends on the stage of VIPoma at diagnosis.[1]
- If the tumor cannot be removed completely, surgical debulking may have palliative effect for control of hormonal symptoms.[2]
- In nonresectable liver metastases, hepatic TACE (transarterial chemoembolization) is emerging as a new non-emergency therapeutic modality highly successful for control of VIP-related symptoms.[3]
References
- ↑ Pancreatic Neuroendocrine Tumors (Islet Cell Tumors). National Cancer Institute. http://www.cancer.gov/types/pancreatic/hp/pnet-treatment-pdq#section/_78. Accessed on October 21, 2015.
- ↑ Vinik A. Vasoactive Intestinal Peptide Tumor (VIPoma) [Updated 2013 Nov 28]. In: De Groot LJ, Beck-Peccoz P, Chrousos G, et al., editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000-. Available from: http://www.ncbi.nlm.nih.gov/books/NBK278960/
- ↑ Blaise A, Girardet JL (1969). "[Study of the magnetic properties of siderophilin]". C R Acad Sci Hebd Seances Acad Sci D. 269 (10): 966–8. PMID 4981295.