Familial adenomatous polyposis laboratory findings: Difference between revisions
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==Overview== | ==Overview== | ||
Laboratory findings that may present with familial adenomatous polyposis include [[anemia]] due to [[gastrointestinal bleeding]] and abnormal [[liver function tests]] due to colon cancer metastasis. | Laboratory findings that may present with familial adenomatous polyposis include [[anemia]] due to [[gastrointestinal bleeding]] and abnormal [[liver function tests]] due to [[Colorectal cancer|colon cancer]] metastasis. | ||
==Laboratory Findings== | ==Laboratory Findings== | ||
Common laboratory findings that may present with familial adenomatous polyposis are:<ref name="pmid11446392">{{cite journal |vauthors=Beech D, Pontius A, Muni N, Long WP |title=Familial adenomatous polyposis: a case report and review of the literature |journal=J Natl Med Assoc |volume=93 |issue=6 |pages=208–13 |year=2001 |pmid=11446392 |pmc=2594024 |doi= |url=}}</ref><ref name="pmid20301519">{{cite journal |vauthors=Adam MP, Ardinger HH, Pagon RA, Wallace SE, Bean LJH, Stephens K, Amemiya A, Jasperson KW, Patel SG, Ahnen DJ |title=APC-Associated Polyposis Conditions. |journal= |volume= |issue= |pages= |year= |pmid=20301519 |doi= |url=}}</ref><ref name="HalfBercovich2009">{{cite journal|last1=Half|first1=Elizabeth|last2=Bercovich|first2=Dani|last3=Rozen|first3=Paul|title=Familial adenomatous polyposis|journal=Orphanet Journal of Rare Diseases|volume=4|issue=1|year=2009|pages=22|issn=1750-1172|doi=10.1186/1750-1172-4-22}}</ref> | Common laboratory findings that may present with familial adenomatous polyposis are:<ref name="pmid11446392">{{cite journal |vauthors=Beech D, Pontius A, Muni N, Long WP |title=Familial adenomatous polyposis: a case report and review of the literature |journal=J Natl Med Assoc |volume=93 |issue=6 |pages=208–13 |year=2001 |pmid=11446392 |pmc=2594024 |doi= |url=}}</ref><ref name="pmid20301519">{{cite journal |vauthors=Adam MP, Ardinger HH, Pagon RA, Wallace SE, Bean LJH, Stephens K, Amemiya A, Jasperson KW, Patel SG, Ahnen DJ |title=APC-Associated Polyposis Conditions. |journal= |volume= |issue= |pages= |year= |pmid=20301519 |doi= |url=}}</ref><ref name="HalfBercovich2009">{{cite journal|last1=Half|first1=Elizabeth|last2=Bercovich|first2=Dani|last3=Rozen|first3=Paul|title=Familial adenomatous polyposis|journal=Orphanet Journal of Rare Diseases|volume=4|issue=1|year=2009|pages=22|issn=1750-1172|doi=10.1186/1750-1172-4-22}}</ref> | ||
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**High [[Aspartate transaminase|aspartate aminotransferase]] ([[Aspartate transaminase|AST]]) (normal - 8 to 48 U/L) | **High [[Aspartate transaminase|aspartate aminotransferase]] ([[Aspartate transaminase|AST]]) (normal - 8 to 48 U/L) | ||
**High [[Alanine transaminase|alanine aminotransferase]] ([[Alanine transaminase|ALT]]) (normal - 7 to 55 units per liter U/L) | **High [[Alanine transaminase|alanine aminotransferase]] ([[Alanine transaminase|ALT]]) (normal - 7 to 55 units per liter U/L) | ||
==References== | ==References== | ||
Revision as of 02:17, 1 February 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Sadaf Sharfaei M.D.[2], Mohamad Alkateb, MBBCh [3]
Overview
Laboratory findings that may present with familial adenomatous polyposis include anemia due to gastrointestinal bleeding and abnormal liver function tests due to colon cancer metastasis.
Laboratory Findings
Common laboratory findings that may present with familial adenomatous polyposis are:[1][2][3]
- Complete blood count
- Low hemoglobin due to gastrointestinal bleeding (normal - 12.1 to 15.1 g/dl for women and 13.8 to 17.2 g/dl for men)
- Elevated platelet count (normal - 150,000 to 450,000 mcL)
- Liver function test due to colon cancer metastasis
- High aspartate aminotransferase (AST) (normal - 8 to 48 U/L)
- High alanine aminotransferase (ALT) (normal - 7 to 55 units per liter U/L)
References
- ↑ Beech D, Pontius A, Muni N, Long WP (2001). "Familial adenomatous polyposis: a case report and review of the literature". J Natl Med Assoc. 93 (6): 208–13. PMC 2594024. PMID 11446392.
- ↑ Adam MP, Ardinger HH, Pagon RA, Wallace SE, Bean L, Stephens K, Amemiya A, Jasperson KW, Patel SG, Ahnen DJ. "APC-Associated Polyposis Conditions". PMID 20301519. Vancouver style error: initials (help)
- ↑ Half, Elizabeth; Bercovich, Dani; Rozen, Paul (2009). "Familial adenomatous polyposis". Orphanet Journal of Rare Diseases. 4 (1): 22. doi:10.1186/1750-1172-4-22. ISSN 1750-1172.