Fat embolism syndrome historical perspective: Difference between revisions
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*In 1875, Czerny explored [[Brain|cerebral]] symptoms associated with FES. | *In 1875, Czerny explored [[Brain|cerebral]] symptoms associated with FES. | ||
*In 1924, Gauss proposed the mechanical theory, which explains that three conditions are necessary for the development of fat embolism: injury to adipose tissue, rupture of veins within the zone of injury, and a mechanism that causes the passage of free fat into the open ends of blood vessel. | *In 1924, Gauss proposed the mechanical theory, which explains that three conditions are necessary for the development of fat embolism: injury to adipose tissue, rupture of veins within the zone of injury, and a mechanism that causes the passage of free fat into the open ends of blood vessel. | ||
*In 1927, Lehman established biochemical theory which states that plasma mediators mobilize fat from body stores and cause the agglutination of bigger fat droplets and hence initiate an inflammatory process. | |||
==Landmark Events in the Development of Treatment Strategies== | ==Landmark Events in the Development of Treatment Strategies== | ||
Revision as of 02:21, 7 March 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Feham Tariq, MD [2]
Overview
Historical Perspective
Discovery
- In 1861, Zenker first discovered fat embolism (FES), after he found pulmonary capillary fat deposition in a patient who suffered from crush injury.
- In 1873, Bergmann described the first clinical case of FES in a patient who suffered a distal femur fracture.
- In 1875, Czerny explored cerebral symptoms associated with FES.
- In 1924, Gauss proposed the mechanical theory, which explains that three conditions are necessary for the development of fat embolism: injury to adipose tissue, rupture of veins within the zone of injury, and a mechanism that causes the passage of free fat into the open ends of blood vessel.
- In 1927, Lehman established biochemical theory which states that plasma mediators mobilize fat from body stores and cause the agglutination of bigger fat droplets and hence initiate an inflammatory process.
Landmark Events in the Development of Treatment Strategies
- In [year], [diagnostic test/therapy] was developed by [scientist] to treat/diagnose [disease name].