Monoclonal gammopathy of undetermined significance causes: Difference between revisions
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{{ Monoclonal gammopathy of undetermined significance }} | {{Monoclonal gammopathy of undetermined significance }} | ||
== Overview == | |||
The most common causes of [[Monoclonal gammopathy of undetermined significance classification]] are genetic mutations. | |||
== Causes[edit | edit source] == | == Causes[edit | edit source] == | ||
[[Monoclonal gammopathy of undetermined significance]] | The most common causes of [[Monoclonal gammopathy of undetermined significance classification]] are genetic mutations. However, there is no established cause of [[Monoclonal gammopathy of undetermined significance classification|progression of Multiple myeloma to Monoclonal gammopathy of undetermined significance classification]] | ||
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|Abnormalities in cytogenes | |Abnormalities in cytogenes | ||
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There is no established system for the staging of [[Monoclonal gammopathy of undetermined significance]] (MGUS). | There is no established system for the staging of [[Monoclonal gammopathy of undetermined significance]] (MGUS). | ||
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Revision as of 15:45, 7 August 2018
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Monoclonal gammopathy of undetermined significance Microchapters |
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Differentiating Monoclonal gammopathy of undetermined significance from other Diseases |
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Overview
The most common causes of Monoclonal gammopathy of undetermined significance classification are genetic mutations.
Causes[edit | edit source]
The most common causes of Monoclonal gammopathy of undetermined significance classification are genetic mutations. However, there is no established cause of progression of Multiple myeloma to Monoclonal gammopathy of undetermined significance classification
| Abnormalities in cytogenes | Affected genes |
| IgH translocation: | |
| t(11;14), q(13;32) | cyclin D1 |
| t(4;14)(p16;q32) | FGFR-3, and MMSET |
| t(14;16)(q32;q23) | C-MAF |
| t(6;14)(q32;q11) | MAFB |
| IgH non-translocated : | |
| Hyper diploid | Numerous |
If the staging system involves specific and characteristic findings and features:
There is no established system for the staging of Monoclonal gammopathy of undetermined significance (MGUS).