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Revision as of 18:07, 14 August 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Priyamvada Singh, M.D. [2]

Overview

Aplastic anemia can be classified into mild, moderate, severe, and very severe depending on the severity of cellularity of bone marrow and the blood tests.

Classification

Aplastic anemia may be classified according to blood cell counts into 3 subgroups:[1]

    • Moderately severe aplastic anemia or non severe AA (nSAA)
    • Severe aplastic anemia (SAA)
    • Very severe aplastic anemia(vSAA)
Classification of aplastic anemia (two out of three criteria must be met)
nSAA SAA vSAA
Reticulocytes <20G/L <20G/L <20G/L
Platelets <50 G / L <20G/L <20G/L
Neutrophilic granulocytes <1.0 G / L <0.5G/L 0.2G/l

This classification is of prognostic relevance and has an influence on therapeutic procedures.

classification based on the presumed etiology
Acquired
Idiopathic
Secondry Irradiation

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References

  1. Dolberg OJ, Levy Y (2014). "Idiopathic aplastic anemia: diagnosis and classification". Autoimmun Rev. 13 (4–5): 569–73. doi:10.1016/j.autrev.2014.01.014. PMID 24424170.