Adrenal insufficiency: Difference between revisions
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==Classification== | ==Classification== | ||
'''[[Adrenal insufficiency]]''' is classified based on the location of the [[pathology]] into: <ref>{{cite web |url=https://www.ncbi.nlm.nih.gov/books/NBK279083/ |title=Adrenal Insufficiency - Endotext - NCBI Bookshelf |format= |work= |accessdate=}}</ref> | |||
*'''[[Primary adrenal insufficiency]]''' | *'''[[Primary adrenal insufficiency]]''' | ||
*'''[[Secondary adrenal insufficiency]]''' | *'''[[Secondary adrenal insufficiency]]''' | ||
*'''Tertiary [[adrenal insufficiency]]''' | *'''Tertiary [[adrenal insufficiency]]''' | ||
In [[Primary adrenal insufficiency]], the [[pathology]] lies in the [[adrenal glands]]. The most common cause of [[primary adrenal insufficiency]] is [[autoimmune adrenalitis]]. In [[secondary adrenal insufficiency]], the [[pathology]] lies in the [[pituitary gland]], whereas in [[ | In [[Primary adrenal insufficiency]], the [[pathology]] lies in the [[adrenal glands]] leading to decreased production of [[cortisol]] and [[aldosterone]].The most common cause of [[primary adrenal insufficiency]] is [[autoimmune adrenalitis]]. In [[secondary adrenal insufficiency]], the [[pathology]] lies in the [[pituitary gland]] leading to reduced [[ACTH]] production, whereas in tertiary [[adrenal insufficiency]] the [[pathology]] lies in the [[hypothalamus]] leading to reduced [[CRH production]]. The most common cause of [[tertiary adrenal insufficiency]] is chronic [[glucocorticoid]] therapy. Secondary and tertiary [[adrenal insufficiency]] together are categorised into central [[adrenal insufficiency]]. The following table summaries the causes of adrenal insufficiency. | ||
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Revision as of 15:57, 2 September 2020
Adrenal insufficiency Microchapters |
Diagnosis |
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Treatment |
Case Studies |
Adrenal insufficiency On the Web |
American Roentgen Ray Society Images of Adrenal insufficiency |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ayeesha Kattubadi, M.B.B.S[2]
Overview
Historical Perspective
Classification
Adrenal insufficiency is classified based on the location of the pathology into: [1]
In Primary adrenal insufficiency, the pathology lies in the adrenal glands leading to decreased production of cortisol and aldosterone.The most common cause of primary adrenal insufficiency is autoimmune adrenalitis. In secondary adrenal insufficiency, the pathology lies in the pituitary gland leading to reduced ACTH production, whereas in tertiary adrenal insufficiency the pathology lies in the hypothalamus leading to reduced CRH production. The most common cause of tertiary adrenal insufficiency is chronic glucocorticoid therapy. Secondary and tertiary adrenal insufficiency together are categorised into central adrenal insufficiency. The following table summaries the causes of adrenal insufficiency.
Causes of adrenal insufficiency | ||
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Primary adrenal insufficiency (Addison's disease) |
Secondary adrenal insufficiency | Tertiary adrenal insufficiency |
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Pathophysiology
Causes
Differentiating Xyz from other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications and Prognosis
Diagnosis
Diagnostic study of choice | History and Symptoms | Physical Examination | Laboratory Findings | Electrocardiogram | X-Ray Findings | Echocardiography and Ultrasound | CT-Scan Findings | MRI Findings | Other Imaging Findings | Other Diagnostic Studies
Treatment
Medical Therapy | Interventions | Surgery | Primary Prevention | Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies