Renal artery stenosis causes: Difference between revisions
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{{Renal artery stenosis}} | {{Renal artery stenosis}} | ||
{{CMG}} | {{CMG}} {{AE}} {{Shivam Singla}} | ||
==Overview== | ==Overview== | ||
Renal artery stenosis is most commonly caused by development of atherosclerotic [[plaque]] in the renal arteries (termed atherosclerotic renal artery stenosis). Less frequently, it is caused by [[fibromuscular dysplasia]]. | Renal artery stenosis is most commonly caused by the development of atherosclerotic [[plaque]] in the renal arteries (termed atherosclerotic renal artery stenosis). Less frequently, it is caused by [[fibromuscular dysplasia]]. | ||
==Causes== | ==Causes== | ||
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Unilateral [[renal artery stenosis]] has two major causes: | Unilateral [[renal artery stenosis]] has two major causes: | ||
1) Atherosclerosis: Most common cause seen in almost 60-90 percent of the cases associated with renal artery stenosis. Atherosclerosis mostly affects men over the age of 45 years and mainly involves the proximal part of the main renal artery. Although this condition is also commonly seen as an isolated lesion even in patients not having the underlying atherosclerotic disease. The risk factors associated with atherosclerosis are Dyslipidemia, cigarette smoking, virus infection, immune damage, and elevated concentrations of homocysteine. | 1) Atherosclerosis: Most common cause seen in almost 60-90 percent of the cases associated with [[renal artery stenosis]]. [[Atherosclerosis]] mostly affects men over the age of 45 years and mainly involves the proximal part of the main [[renal artery]]. Although this condition is also commonly seen as an isolated lesion even in patients not having the underlying [[atherosclerotic]] [[disease]]. The [[risk factors]] associated with [[atherosclerosis]] are [[Dyslipidemia]], [[cigarette smoking]], [[virus]] [[infection]], [[immune]] damage, and elevated concentrations of [[homocysteine]]. | ||
2) Fibromuscular dysplasia: This is responsible for causing renal artery stenosis in the remaining 10-30 percent of cases. This is most commonly seen in women | 2) Fibromuscular dysplasia: This is responsible for causing [[renal artery stenosis]] in the remaining 10-30 percent of cases. This is most commonly seen in women under the age of 50 years and mainly involves middle and distal [[renal arteries]]and typically involves the middle and distal main [[renal artery]] or the [[intrarenal]] branches. | ||
3) In, Less than 10 percent of the patient population other less common factors play a role like thromboembolic disease, aortic aneurysms, Takayasu arteritis, polyarteritis nodosa, and retroperitoneal fibrosis. | 3) In, Less than 10 percent of the patient population other less common factors play a role like [[thromboembolic]] [[disease]], [[aortic aneurysms]], [[Takayasu arteritis]], [[polyarteritis nodosa]], and [[retroperitoneal fibrosis]]. | ||
==References== | ==References== | ||
Revision as of 04:16, 3 December 2020
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Shivam Singla, M.D.[2]
Overview
Renal artery stenosis is most commonly caused by the development of atherosclerotic plaque in the renal arteries (termed atherosclerotic renal artery stenosis). Less frequently, it is caused by fibromuscular dysplasia.
Causes
Unilateral renal artery stenosis has two major causes:
1) Atherosclerosis: Most common cause seen in almost 60-90 percent of the cases associated with renal artery stenosis. Atherosclerosis mostly affects men over the age of 45 years and mainly involves the proximal part of the main renal artery. Although this condition is also commonly seen as an isolated lesion even in patients not having the underlying atherosclerotic disease. The risk factors associated with atherosclerosis are Dyslipidemia, cigarette smoking, virus infection, immune damage, and elevated concentrations of homocysteine.
2) Fibromuscular dysplasia: This is responsible for causing renal artery stenosis in the remaining 10-30 percent of cases. This is most commonly seen in women under the age of 50 years and mainly involves middle and distal renal arteriesand typically involves the middle and distal main renal artery or the intrarenal branches.
3) In, Less than 10 percent of the patient population other less common factors play a role like thromboembolic disease, aortic aneurysms, Takayasu arteritis, polyarteritis nodosa, and retroperitoneal fibrosis.