Fever of unknown origin overview: Difference between revisions
| Line 10: | Line 10: | ||
==Overview== | ==Overview== | ||
Fever of unknown origin was formally defined for the first time by Petersdorf and Beeson: “fever above 38.3° C (100.9° F) on several occasions, persisting without diagnosis for at least three weeks in spite of at least one week’s investigation in hospital.ʺ<ref name="AuwaerterWright2020">{{cite journal|last1=Auwaerter|first1=Paul G|last2=Wright|first2=William F|title=Fever and Fever of Unknown Origin: Review, Recent Advances, and Lingering Dogma|journal=Open Forum Infectious Diseases|volume=7|issue=5|year=2020|issn=2328-8957|doi=10.1093/ofid/ofaa132}}</ref> | Fever of unknown origin (FUO) was formally defined for the first time by Petersdorf and Beeson: “fever above 38.3° C (100.9° F) on several occasions, persisting without diagnosis for at least three weeks in spite of at least one week’s investigation in hospital.ʺ<ref name="AuwaerterWright2020">{{cite journal|last1=Auwaerter|first1=Paul G|last2=Wright|first2=William F|title=Fever and Fever of Unknown Origin: Review, Recent Advances, and Lingering Dogma|journal=Open Forum Infectious Diseases|volume=7|issue=5|year=2020|issn=2328-8957|doi=10.1093/ofid/ofaa132}}</ref> | ||
Durack and Street made four different categories of fever of unknown origin in 1991: | |||
# Classic FUO | |||
# Nosocomial FUO | |||
# Neutropenic FUO | |||
# HIV related FUO<ref name="pmid1651090">{{cite journal| author=Durack DT, Street AC| title=Fever of unknown origin--reexamined and redefined. | journal=Curr Clin Top Infect Dis | year= 1991 | volume= 11 | issue= | pages= 35-51 | pmid=1651090 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1651090 }}</ref> | |||
==Pathophysiology== | ==Pathophysiology== | ||
Revision as of 22:12, 17 January 2021
|
Resident Survival Guide |
|
Fever of unknown origin Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Fever of unknown origin overview On the Web |
|
American Roentgen Ray Society Images of Fever of unknown origin overview |
|
Risk calculators and risk factors for Fever of unknown origin overview |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Synonyms and keywords: febris continua e causa ignota; febris e causa ignota; febris E.C.I.; FUO; PUO; pyrexia of unknown origin
Overview
Fever of unknown origin (FUO) was formally defined for the first time by Petersdorf and Beeson: “fever above 38.3° C (100.9° F) on several occasions, persisting without diagnosis for at least three weeks in spite of at least one week’s investigation in hospital.ʺ[1]
Durack and Street made four different categories of fever of unknown origin in 1991:
- Classic FUO
- Nosocomial FUO
- Neutropenic FUO
- HIV related FUO[2]
Pathophysiology
The current definition requires three outpatient visits or three days in hospital or 1 week of "intelligent and invasive" ambulatory investigation.
References
- ↑ Auwaerter, Paul G; Wright, William F (2020). "Fever and Fever of Unknown Origin: Review, Recent Advances, and Lingering Dogma". Open Forum Infectious Diseases. 7 (5). doi:10.1093/ofid/ofaa132. ISSN 2328-8957.
- ↑ Durack DT, Street AC (1991). "Fever of unknown origin--reexamined and redefined". Curr Clin Top Infect Dis. 11: 35–51. PMID 1651090.