Fever of unknown origin overview: Difference between revisions
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Durack and Street made four different categories of fever of unknown origin in 1991: | Durack and Street made four different categories of fever of unknown origin in 1991: | ||
# Classic FUO | #Classic FUO | ||
# Nosocomial FUO | #Nosocomial FUO | ||
# Neutropenic FUO | #Neutropenic FUO | ||
# HIV related FUO<ref name=" | #HIV related FUO<ref name="AuwaerterWright20202">{{cite journal|last1=Auwaerter|first1=Paul G|last2=Wright|first2=William F|title=Fever and Fever of Unknown Origin: Review, Recent Advances, and Lingering Dogma|journal=Open Forum Infectious Diseases|volume=7|issue=5|year=2020|issn=2328-8957|doi=10.1093/ofid/ofaa132}}</ref> | ||
==Pathophysiology== | ==Pathophysiology== |
Revision as of 22:23, 17 January 2021
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Synonyms and keywords: febris continua e causa ignota; febris e causa ignota; febris E.C.I.; FUO; PUO; pyrexia of unknown origin
Overview
Fever of unknown origin (FUO) was formally defined for the first time by Petersdorf and Beeson: “fever above 38.3° C (100.9° F) on several occasions, persisting without diagnosis for at least three weeks in spite of at least one week’s investigation in hospital.ʺ[1]
Durack and Street made four different categories of fever of unknown origin in 1991:
- Classic FUO
- Nosocomial FUO
- Neutropenic FUO
- HIV related FUO[2]
Pathophysiology
The current definition requires three outpatient visits or three days in hospital or 1 week of "intelligent and invasive" ambulatory investigation.
References
- ↑ Auwaerter, Paul G; Wright, William F (2020). "Fever and Fever of Unknown Origin: Review, Recent Advances, and Lingering Dogma". Open Forum Infectious Diseases. 7 (5). doi:10.1093/ofid/ofaa132. ISSN 2328-8957.
- ↑ Auwaerter, Paul G; Wright, William F (2020). "Fever and Fever of Unknown Origin: Review, Recent Advances, and Lingering Dogma". Open Forum Infectious Diseases. 7 (5). doi:10.1093/ofid/ofaa132. ISSN 2328-8957.