Fever of unknown origin causes: Difference between revisions
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Etiology is different for different categories of FUO: | Etiology is different for different categories of FUO: | ||
=== Classic FUO === | ===Classic FUO=== | ||
# Malignancies such as Hodgkin and non-Hodgkin lymphoma, myeloproliferative disorders, malignancy of colon and liver. | #Malignancies such as Hodgkin and non-Hodgkin lymphoma, myeloproliferative disorders, malignancy of colon and liver. | ||
# Infections such as intrabdominal and pelvic abscesses, inflammation of the endocardium, tuberculosis, cat scratch disease, CMV and EBV infections. | #Infections such as intrabdominal and pelvic abscesses, inflammation of the endocardium, tuberculosis, cat scratch disease, CMV and EBV infections. | ||
# Inflammatory causes such as autoimmune diseases (systemic lupus erythematosus, Rheumatoid arthritis) and polymyalgia rheumatica. | #Inflammatory causes such as autoimmune diseases (systemic lupus erythematosus, Rheumatoid arthritis) and polymyalgia rheumatica.<ref name="HayakawaRamasamy2012">{{cite journal|last1=Hayakawa|first1=Kayoko|last2=Ramasamy|first2=Balaji|last3=Chandrasekar|first3=Pranatharthi H.|title=Fever of Unknown Origin: An Evidence-Based Review|journal=The American Journal of the Medical Sciences|volume=344|issue=4|year=2012|pages=307–316|issn=00029629|doi=10.1097/MAJ.0b013e31824ae504}}</ref> | ||
=== Neutropenic FUO === | ===Neutropenic FUO=== | ||
These are mostly caused by bacterial, fungal and viral infection because of the decreased neutrophil count. | These are mostly caused by bacterial, fungal and viral infection because of the decreased neutrophil count.<ref name="HayakawaRamasamy20122">{{cite journal|last1=Hayakawa|first1=Kayoko|last2=Ramasamy|first2=Balaji|last3=Chandrasekar|first3=Pranatharthi H.|title=Fever of Unknown Origin: An Evidence-Based Review|journal=The American Journal of the Medical Sciences|volume=344|issue=4|year=2012|pages=307–316|issn=00029629|doi=10.1097/MAJ.0b013e31824ae504}}</ref> | ||
=== HIV associated FUO === | ===HIV associated FUO=== | ||
This may due to acute infection from HIV itself earlier or later due to opportunistic bacterial, fungal and viral infections such as mycobacteria, toxoplasma etc. | This may due to acute infection from HIV itself earlier or later due to opportunistic bacterial, fungal and viral infections such as mycobacteria, toxoplasma etc.<ref name="HayakawaRamasamy20123">{{cite journal|last1=Hayakawa|first1=Kayoko|last2=Ramasamy|first2=Balaji|last3=Chandrasekar|first3=Pranatharthi H.|title=Fever of Unknown Origin: An Evidence-Based Review|journal=The American Journal of the Medical Sciences|volume=344|issue=4|year=2012|pages=307–316|issn=00029629|doi=10.1097/MAJ.0b013e31824ae504}}</ref> | ||
=== Nosocomial FUO === | ===Nosocomial FUO=== | ||
Causes of nosocomial FUO are related to hospital setting such as drugs, infections acquired during hospitalization and complications that occur during and after surgery. | Causes of nosocomial FUO are related to hospital setting such as drugs, infections acquired during hospitalization and complications that occur during and after surgery.<ref name="HayakawaRamasamy20124">{{cite journal|last1=Hayakawa|first1=Kayoko|last2=Ramasamy|first2=Balaji|last3=Chandrasekar|first3=Pranatharthi H.|title=Fever of Unknown Origin: An Evidence-Based Review|journal=The American Journal of the Medical Sciences|volume=344|issue=4|year=2012|pages=307–316|issn=00029629|doi=10.1097/MAJ.0b013e31824ae504}}</ref> | ||
==== References ==== | ====References==== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
[[Category:Ailments of unknown etiology]] | [[Category:Ailments of unknown etiology]] |
Revision as of 22:46, 21 January 2021
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Naresh Mullaguri, M.B.B.S. [2]
Synonyms and keywords: febris continua e causa ignota; febris e causa ignota; febris E.C.I.; FUO; PUO; pyrexia of unknown origin
Causes
Etiology is different for different categories of FUO:
Classic FUO
- Malignancies such as Hodgkin and non-Hodgkin lymphoma, myeloproliferative disorders, malignancy of colon and liver.
- Infections such as intrabdominal and pelvic abscesses, inflammation of the endocardium, tuberculosis, cat scratch disease, CMV and EBV infections.
- Inflammatory causes such as autoimmune diseases (systemic lupus erythematosus, Rheumatoid arthritis) and polymyalgia rheumatica.[1]
Neutropenic FUO
These are mostly caused by bacterial, fungal and viral infection because of the decreased neutrophil count.[2]
HIV associated FUO
This may due to acute infection from HIV itself earlier or later due to opportunistic bacterial, fungal and viral infections such as mycobacteria, toxoplasma etc.[3]
Nosocomial FUO
Causes of nosocomial FUO are related to hospital setting such as drugs, infections acquired during hospitalization and complications that occur during and after surgery.[4]
References
- ↑ Hayakawa, Kayoko; Ramasamy, Balaji; Chandrasekar, Pranatharthi H. (2012). "Fever of Unknown Origin: An Evidence-Based Review". The American Journal of the Medical Sciences. 344 (4): 307–316. doi:10.1097/MAJ.0b013e31824ae504. ISSN 0002-9629.
- ↑ Hayakawa, Kayoko; Ramasamy, Balaji; Chandrasekar, Pranatharthi H. (2012). "Fever of Unknown Origin: An Evidence-Based Review". The American Journal of the Medical Sciences. 344 (4): 307–316. doi:10.1097/MAJ.0b013e31824ae504. ISSN 0002-9629.
- ↑ Hayakawa, Kayoko; Ramasamy, Balaji; Chandrasekar, Pranatharthi H. (2012). "Fever of Unknown Origin: An Evidence-Based Review". The American Journal of the Medical Sciences. 344 (4): 307–316. doi:10.1097/MAJ.0b013e31824ae504. ISSN 0002-9629.
- ↑ Hayakawa, Kayoko; Ramasamy, Balaji; Chandrasekar, Pranatharthi H. (2012). "Fever of Unknown Origin: An Evidence-Based Review". The American Journal of the Medical Sciences. 344 (4): 307–316. doi:10.1097/MAJ.0b013e31824ae504. ISSN 0002-9629.