Fever of unknown origin causes: Difference between revisions
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===Classic FUO=== | ===Classic FUO=== | ||
#Malignancies such as Hodgkin and non-Hodgkin lymphoma, myeloproliferative disorders, | #Malignancies such as [[Hodgkin's lymphoma|Hodgkin]] and [[Non-Hodgkin lymphoma|non-Hodgkin]] lymphoma, [[Myeloproliferative neoplasm|myeloproliferative]] disorders, [[colorectal carcinoma]] and carcinoma of liver. | ||
#Infections such as intrabdominal and pelvic abscesses, inflammation of the endocardium, tuberculosis, cat scratch disease, CMV and EBV infections. | #Infections such as intrabdominal and pelvic [[abscesses]], inflammation of the endocardium, [[tuberculosis]], [[cat scratch disease]], [[CMV infection|CMV]] and [[Epstein Barr virus|EBV]] infections. | ||
#Inflammatory causes such as autoimmune diseases (systemic lupus erythematosus, Rheumatoid arthritis) and polymyalgia rheumatica.<ref name="HayakawaRamasamy2012">{{cite journal|last1=Hayakawa|first1=Kayoko|last2=Ramasamy|first2=Balaji|last3=Chandrasekar|first3=Pranatharthi H.|title=Fever of Unknown Origin: An Evidence-Based Review|journal=The American Journal of the Medical Sciences|volume=344|issue=4|year=2012|pages=307–316|issn=00029629|doi=10.1097/MAJ.0b013e31824ae504}}</ref> | #Inflammatory causes such as autoimmune diseases ([[systemic lupus erythematosus]], [[Rheumatoid arthritis]]) and [[polymyalgia rheumatica]].<ref name="HayakawaRamasamy2012">{{cite journal|last1=Hayakawa|first1=Kayoko|last2=Ramasamy|first2=Balaji|last3=Chandrasekar|first3=Pranatharthi H.|title=Fever of Unknown Origin: An Evidence-Based Review|journal=The American Journal of the Medical Sciences|volume=344|issue=4|year=2012|pages=307–316|issn=00029629|doi=10.1097/MAJ.0b013e31824ae504}}</ref> | ||
===Neutropenic FUO=== | ===Neutropenic FUO=== | ||
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===HIV associated FUO=== | ===HIV associated FUO=== | ||
This may due to acute infection from HIV itself earlier or later due to opportunistic bacterial, fungal and viral infections such as mycobacteria, toxoplasma etc.<ref name="HayakawaRamasamy20123">{{cite journal|last1=Hayakawa|first1=Kayoko|last2=Ramasamy|first2=Balaji|last3=Chandrasekar|first3=Pranatharthi H.|title=Fever of Unknown Origin: An Evidence-Based Review|journal=The American Journal of the Medical Sciences|volume=344|issue=4|year=2012|pages=307–316|issn=00029629|doi=10.1097/MAJ.0b013e31824ae504}}</ref> | This may due to acute infection from HIV itself earlier or later due to [[Opportunistic infection|opportunistic]] bacterial, fungal and viral infections such as [[mycobacteria]], [[Toxoplasmosis|toxoplasma]] etc.<ref name="HayakawaRamasamy20123">{{cite journal|last1=Hayakawa|first1=Kayoko|last2=Ramasamy|first2=Balaji|last3=Chandrasekar|first3=Pranatharthi H.|title=Fever of Unknown Origin: An Evidence-Based Review|journal=The American Journal of the Medical Sciences|volume=344|issue=4|year=2012|pages=307–316|issn=00029629|doi=10.1097/MAJ.0b013e31824ae504}}</ref> | ||
===Nosocomial FUO=== | ===Nosocomial FUO=== | ||
Revision as of 15:50, 25 January 2021
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Naresh Mullaguri, M.B.B.S. [2]
Synonyms and keywords: febris continua e causa ignota; febris e causa ignota; febris E.C.I.; FUO; PUO; pyrexia of unknown origin
Causes
Etiology is different for different categories of FUO:
Classic FUO
- Malignancies such as Hodgkin and non-Hodgkin lymphoma, myeloproliferative disorders, colorectal carcinoma and carcinoma of liver.
- Infections such as intrabdominal and pelvic abscesses, inflammation of the endocardium, tuberculosis, cat scratch disease, CMV and EBV infections.
- Inflammatory causes such as autoimmune diseases (systemic lupus erythematosus, Rheumatoid arthritis) and polymyalgia rheumatica.[1]
Neutropenic FUO
These are mostly caused by bacterial, fungal and viral infection because of the decreased neutrophil count.[2]
HIV associated FUO
This may due to acute infection from HIV itself earlier or later due to opportunistic bacterial, fungal and viral infections such as mycobacteria, toxoplasma etc.[3]
Nosocomial FUO
Causes of nosocomial FUO are related to hospital setting such as drugs, infections acquired during hospitalization and complications that occur during and after surgery.[4]
References
- ↑ Hayakawa, Kayoko; Ramasamy, Balaji; Chandrasekar, Pranatharthi H. (2012). "Fever of Unknown Origin: An Evidence-Based Review". The American Journal of the Medical Sciences. 344 (4): 307–316. doi:10.1097/MAJ.0b013e31824ae504. ISSN 0002-9629.
- ↑ Hayakawa, Kayoko; Ramasamy, Balaji; Chandrasekar, Pranatharthi H. (2012). "Fever of Unknown Origin: An Evidence-Based Review". The American Journal of the Medical Sciences. 344 (4): 307–316. doi:10.1097/MAJ.0b013e31824ae504. ISSN 0002-9629.
- ↑ Hayakawa, Kayoko; Ramasamy, Balaji; Chandrasekar, Pranatharthi H. (2012). "Fever of Unknown Origin: An Evidence-Based Review". The American Journal of the Medical Sciences. 344 (4): 307–316. doi:10.1097/MAJ.0b013e31824ae504. ISSN 0002-9629.
- ↑ Wright WF, Auwaerter PG (2020). "Fever and Fever of Unknown Origin: Review, Recent Advances, and Lingering Dogma". Open Forum Infect Dis. 7 (5): ofaa132. doi:10.1093/ofid/ofaa132. PMC 7237822 Check
|pmc=value (help). PMID 32462043 Check|pmid=value (help).