B-cell lymphoma epidemiology and demographics: Difference between revisions
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[[Non-Hodgkin lymphoma]] (NHL) commonly affects individuals older than 65 years of age. However, some subtypes of NHL (i.e., [[Burkitt lymphoma]]) show a bimodal age distribution. [[Hodgkin's lymphoma]] has a bimodal age distribution with the highest incidence in patients (20-39) years of age and older than 60 years of age.<ref name="pmid31640759">{{cite journal |vauthors=Zhou L, Deng Y, Li N, Zheng Y, Tian T, Zhai Z, Yang S, Hao Q, Wu Y, Song D, Zhang D, Lyu J, Dai Z |title=Global, regional, and national burden of Hodgkin lymphoma from 1990 to 2017: estimates from the 2017 Global Burden of Disease study |journal=J Hematol Oncol |volume=12 |issue=1 |pages=107 |date=October 2019 |pmid=31640759 |pmc=6805485 |doi=10.1186/s13045-019-0799-1 |url=}}</ref> | [[Non-Hodgkin lymphoma]] (NHL) commonly affects individuals older than 65 years of age. However, some subtypes of NHL (i.e., [[Burkitt lymphoma]]) show a bimodal age distribution. [[Hodgkin's lymphoma]] has a bimodal age distribution with the highest incidence in patients (20-39) years of age and older than 60 years of age.<ref name="pmid31640759">{{cite journal |vauthors=Zhou L, Deng Y, Li N, Zheng Y, Tian T, Zhai Z, Yang S, Hao Q, Wu Y, Song D, Zhang D, Lyu J, Dai Z |title=Global, regional, and national burden of Hodgkin lymphoma from 1990 to 2017: estimates from the 2017 Global Burden of Disease study |journal=J Hematol Oncol |volume=12 |issue=1 |pages=107 |date=October 2019 |pmid=31640759 |pmc=6805485 |doi=10.1186/s13045-019-0799-1 |url=}}</ref> | ||
===Race=== | ===Race=== | ||
In the US, [[Non-Hodgkin lymphoma]] (NHL) usually affects individuals of the white and non-Hispanic races. Asian/Pacific Islander, American Indian and black individuals are less likely to develop NHL.<ref name="pmid33573146">{{cite journal |vauthors=Thandra KC, Barsouk A, Saginala K, Padala SA, Barsouk A, Rawla P |title=Epidemiology of Non-Hodgkin's Lymphoma |journal=Med Sci (Basel) |volume=9 |issue=1 |pages= |date=January 2021 |pmid=33573146 |pmc=7930980 |doi=10.3390/medsci9010005 |url=}}</ref>. Hodgkin's lymphoma shows age-specific racial disparities. In patients aged <65 years, individuals of the white race have the highest incidence of Hodgkin's lymphoma. On the other hand, in patients over 65 years old, individuals of Hispanics have the highest incidence of Hodgkin's lymphoma. Regardless of the age, Asian/Pacific Islanders (A/PI) are less likely to develop Hodgkin's lymphoma.<ref name="pmid22241896">{{cite journal |vauthors=Evens AM, Antillón M, Aschebrook-Kilfoy B, Chiu BC |title=Racial disparities in Hodgkin's lymphoma: a comprehensive population-based analysis |journal=Ann Oncol |volume=23 |issue=8 |pages=2128–2137 |date=August 2012 |pmid=22241896 |doi=10.1093/annonc/mdr578 |url=}}</ref> | |||
===Gender=== | ===Gender=== | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Adnan Ezici, M.D[2]
Overview
Epidemiology and Demographics
Incidence
The incidence of non-Hodgkin lymphoma is approximately 18.6 per 100,000 individuals worldwide.[1] The incidence of Hodgkin's lymphoma is approximately 2-3 per 100,000 individuals in populations of European ancestry.[2]
Prevalence
Case-fatality rate/Mortality rate
In year 2018, the mortality rate of non-Hodgkin lymphoma is approximately 5.1/100,000.[1] In year 2017, the mortality rate of Hodgkin's lymphoma is approximately 0.41/100,000.[3]
Age
Non-Hodgkin lymphoma (NHL) commonly affects individuals older than 65 years of age. However, some subtypes of NHL (i.e., Burkitt lymphoma) show a bimodal age distribution. Hodgkin's lymphoma has a bimodal age distribution with the highest incidence in patients (20-39) years of age and older than 60 years of age.[3]
Race
In the US, Non-Hodgkin lymphoma (NHL) usually affects individuals of the white and non-Hispanic races. Asian/Pacific Islander, American Indian and black individuals are less likely to develop NHL.[1]. Hodgkin's lymphoma shows age-specific racial disparities. In patients aged <65 years, individuals of the white race have the highest incidence of Hodgkin's lymphoma. On the other hand, in patients over 65 years old, individuals of Hispanics have the highest incidence of Hodgkin's lymphoma. Regardless of the age, Asian/Pacific Islanders (A/PI) are less likely to develop Hodgkin's lymphoma.[4]
Gender
Region
References
- ↑ 1.0 1.1 1.2 Thandra KC, Barsouk A, Saginala K, Padala SA, Barsouk A, Rawla P (January 2021). "Epidemiology of Non-Hodgkin's Lymphoma". Med Sci (Basel). 9 (1). doi:10.3390/medsci9010005. PMC 7930980 Check
|pmc=
value (help). PMID 33573146 Check|pmid=
value (help). - ↑ Connors JM, Cozen W, Steidl C, Carbone A, Hoppe RT, Flechtner HH, Bartlett NL (July 2020). "Hodgkin lymphoma". Nat Rev Dis Primers. 6 (1): 61. doi:10.1038/s41572-020-0189-6. PMID 32703953 Check
|pmid=
value (help). - ↑ 3.0 3.1 Zhou L, Deng Y, Li N, Zheng Y, Tian T, Zhai Z, Yang S, Hao Q, Wu Y, Song D, Zhang D, Lyu J, Dai Z (October 2019). "Global, regional, and national burden of Hodgkin lymphoma from 1990 to 2017: estimates from the 2017 Global Burden of Disease study". J Hematol Oncol. 12 (1): 107. doi:10.1186/s13045-019-0799-1. PMC 6805485 Check
|pmc=
value (help). PMID 31640759. - ↑ Evens AM, Antillón M, Aschebrook-Kilfoy B, Chiu BC (August 2012). "Racial disparities in Hodgkin's lymphoma: a comprehensive population-based analysis". Ann Oncol. 23 (8): 2128–2137. doi:10.1093/annonc/mdr578. PMID 22241896.