Haff disease natural history, complications and prognosis: Difference between revisions
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As Haff disease is a rare clinical syndrome, it is oftentimes misdiagnosed. Early diagnosis and treatment are required to prevent the development of complications. | As Haff disease is a rare clinical syndrome, it is oftentimes misdiagnosed. Early diagnosis and treatment are required to prevent the development of complications. | ||
It has an incubation period of eight hours, and presents with nausea, vomiting, myalgias, muscle rigidity, chest pain (mimicking myocardial infarction), diaphoresis, dyspnea, and brown urine indicating myoglobinuria. As it is a self limiting condition with good prognosis, most patients recover in 2-5 days. Haff disease is rarely associated with mortality, but some cases may develop complications such as renal and other organ failures. <ref name="pmid25978748">{{cite journal| author=Diaz J| title=Don't be Half-Educated About Haff Disease in Louisiana. | journal=J La State Med Soc | year= 2015 | volume= 167 | issue= 1 | pages= 6-10 | pmid=25978748 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25978748 }} </ref> | It has an incubation period of eight hours, and presents with nausea, vomiting, myalgias, muscle rigidity, chest pain (mimicking [[myocardial infarction]]), diaphoresis, dyspnea, and brown urine indicating [[myoglobinuria]]. As it is a self limiting condition with good prognosis, most patients recover in 2-5 days. Haff disease is rarely associated with mortality, but some cases may develop complications such as [[Acute renal failure|renal]] and other organ failures. <ref name="pmid25978748">{{cite journal| author=Diaz J| title=Don't be Half-Educated About Haff Disease in Louisiana. | journal=J La State Med Soc | year= 2015 | volume= 167 | issue= 1 | pages= 6-10 | pmid=25978748 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25978748 }} </ref> | ||
==References== | ==References== |
Revision as of 22:15, 1 April 2022
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: M. Hassan, M.B.B.S
Overview
Natural history, Complications and Prognosis
As Haff disease is a rare clinical syndrome, it is oftentimes misdiagnosed. Early diagnosis and treatment are required to prevent the development of complications.
It has an incubation period of eight hours, and presents with nausea, vomiting, myalgias, muscle rigidity, chest pain (mimicking myocardial infarction), diaphoresis, dyspnea, and brown urine indicating myoglobinuria. As it is a self limiting condition with good prognosis, most patients recover in 2-5 days. Haff disease is rarely associated with mortality, but some cases may develop complications such as renal and other organ failures. [1]
References
- ↑ Diaz J (2015). "Don't be Half-Educated About Haff Disease in Louisiana". J La State Med Soc. 167 (1): 6–10. PMID 25978748.