Haff disease laboratory findings: Difference between revisions
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Currently, the following criteria is used to define cases of Haff disease: | <ref name="pmid31843046">{{cite journal| author=Pei P, Li XY, Lu SS, Liu Z, Wang R, Lu XC | display-authors=etal| title=The Emergence, Epidemiology, and Etiology of Haff Disease. | journal=Biomed Environ Sci | year= 2019 | volume= 32 | issue= 10 | pages= 769-778 | pmid=31843046 | doi=10.3967/bes2019.096 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=31843046 }} </ref>Currently, the following diagnostic criteria is used to define cases of Haff disease: | ||
# A history of consumption of cooked fish within 24 hours prior to the onset of symptoms | #A history of consumption of cooked fish within 24 hours prior to the onset of symptoms | ||
# Elevated serum creatine phosphokinase (more than fivefold) | #Elevated serum creatine phosphokinase (more than fivefold) | ||
# CK-MB fraction of <5% | #CK-MB fraction of <5% | ||
==References== | ==References== |
Revision as of 03:17, 22 April 2022
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: M. Hassan, M.B.B.S
Overview
Laboratory findings
Since Haff disease causes rhabdomyolysis, the approach to the evaluation of rhabdomyolysis should be as follows:
- CBC (complete blood count)
- Creatine kinase (three-five times the upper limit of normal values of 100 to 400 IU/L)[1]
- Chemistries (hyperkalemia, hyperphosphatemia, and hypocalcemia)
- Liver function test
- Urine pH
- Urinalysis
- Blood (+)
- No red blood cells on microscopy (seen in either hemoglobinuria or myoglobinuria)
[2]Currently, the following diagnostic criteria is used to define cases of Haff disease:
- A history of consumption of cooked fish within 24 hours prior to the onset of symptoms
- Elevated serum creatine phosphokinase (more than fivefold)
- CK-MB fraction of <5%
References
- ↑ "StatPearls". 2022. PMID 28846335.
- ↑ Pei P, Li XY, Lu SS, Liu Z, Wang R, Lu XC; et al. (2019). "The Emergence, Epidemiology, and Etiology of Haff Disease". Biomed Environ Sci. 32 (10): 769–778. doi:10.3967/bes2019.096. PMID 31843046.