Capillary leak syndrome cost-effectiveness of therapy: Difference between revisions
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|'''[[Epoprostenol]]''' | |'''[[Epoprostenol]]''' | ||
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* Over a two 6-month period, [[epoprostenol]] was estimated to cost around $19,483.48. This did not include equipment use of $283.25 which brought the total cost near $19,766.73<ref name="pmid10144080">{{cite journal| author=Petros AJ, Turner SC, Nunn AJ| title=Cost implications of using inhaled nitric oxide compared with epoprostenol for pulmonary hypertension. | journal=J Pharm Technol | year= 1995 | volume= 11 | issue= 4 | pages= 163-6 | pmid=10144080 | doi=10.1177/875512259501100409 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10144080 }}</ref> | *Over a two 6-month period, [[epoprostenol]] was estimated to cost around $19,483.48. This did not include equipment use of $283.25 which brought the total cost near $19,766.73<ref name="pmid10144080">{{cite journal| author=Petros AJ, Turner SC, Nunn AJ| title=Cost implications of using inhaled nitric oxide compared with epoprostenol for pulmonary hypertension. | journal=J Pharm Technol | year= 1995 | volume= 11 | issue= 4 | pages= 163-6 | pmid=10144080 | doi=10.1177/875512259501100409 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10144080 }}</ref> | ||
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|'''[[Theophylline]] + [[Terbutaline]]''' | |'''[[Theophylline]] + [[Terbutaline]]''' | ||
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*Due to the risk of toxicity, [[Theophylline]] requires increased monitoring. Due to this, costs can average around $121.40 per patient per month <ref name="pmid8449051">{{cite journal| author=Jubran A, Gross N, Ramsdell J, Simonian R, Schuttenhelm K, Sax M | display-authors=etal| title=Comparative cost-effectiveness analysis of theophylline and ipratropium bromide in chronic obstructive pulmonary disease. A three-center study. | journal=Chest | year= 1993 | volume= 103 | issue= 3 | pages= 678-84 | pmid=8449051 | doi=10.1378/chest.103.3.678 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8449051 }}</ref> | *Due to the risk of toxicity, [[Theophylline]] requires increased monitoring. Due to this, costs can average around $121.40 per patient per month <ref name="pmid8449051">{{cite journal| author=Jubran A, Gross N, Ramsdell J, Simonian R, Schuttenhelm K, Sax M | display-authors=etal| title=Comparative cost-effectiveness analysis of theophylline and ipratropium bromide in chronic obstructive pulmonary disease. A three-center study. | journal=Chest | year= 1993 | volume= 103 | issue= 3 | pages= 678-84 | pmid=8449051 | doi=10.1378/chest.103.3.678 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8449051 }}</ref> | ||
*After studying admission for 13 days and 16 days, [[Theophylline]] costs were estimated to be around $12,864.22<ref name="pmid1482803">{{cite journal| author=Hamilton RA, Gordon T| title=Incidence and cost of hospital admissions secondary to drug interactions involving theophylline. | journal=Ann Pharmacother | year= 1992 | volume= 26 | issue= 12 | pages= 1507-11 | pmid=1482803 | doi=10.1177/106002809202601202 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1482803 }}</ref> | |||
*Compared to other [[Tocolytic|tocolytics]], [[Terbutaline]] required increased monitoring due to a higher incidence of adverse events resulting in an average cost of $399.02. Comparatively, [[nifedipine]] had an average cost of $16.75<ref name="pmid17904969">{{cite journal| author=Hayes E, Moroz L, Pizzi L, Baxter J| title=A cost decision analysis of 4 tocolytic drugs. | journal=Am J Obstet Gynecol | year= 2007 | volume= 197 | issue= 4 | pages= 383.e1-6 | pmid=17904969 | doi=10.1016/j.ajog.2007.06.052 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17904969 }}</ref> | *Compared to other [[Tocolytic|tocolytics]], [[Terbutaline]] required increased monitoring due to a higher incidence of adverse events resulting in an average cost of $399.02. Comparatively, [[nifedipine]] had an average cost of $16.75<ref name="pmid17904969">{{cite journal| author=Hayes E, Moroz L, Pizzi L, Baxter J| title=A cost decision analysis of 4 tocolytic drugs. | journal=Am J Obstet Gynecol | year= 2007 | volume= 197 | issue= 4 | pages= 383.e1-6 | pmid=17904969 | doi=10.1016/j.ajog.2007.06.052 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17904969 }}</ref> | ||
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Revision as of 06:17, 8 August 2022
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: M. Hassan, M.B.B.S
Overview
Cost-effective therapy
Treatment | Mechanism of Action |
---|---|
Endothelial signal transduction | |
Bevacizumab |
|
Epoprostenol |
|
Theophylline + Terbutaline |
|
Immune modulation | |
Corticosteroids | |
Infliximab | |
IVIG | |
Plasmapheresis |
References
- ↑ "Bevacizumab Wins Cost-Effectiveness Contest in First-Line Metastatic Colorectal Cancer". Am Health Drug Benefits. 8 (Spec Issue): 10–2. 2015. PMC 4570073. PMID 26380601.
- ↑ Petros AJ, Turner SC, Nunn AJ (1995). "Cost implications of using inhaled nitric oxide compared with epoprostenol for pulmonary hypertension". J Pharm Technol. 11 (4): 163–6. doi:10.1177/875512259501100409. PMID 10144080.
- ↑ Jubran A, Gross N, Ramsdell J, Simonian R, Schuttenhelm K, Sax M; et al. (1993). "Comparative cost-effectiveness analysis of theophylline and ipratropium bromide in chronic obstructive pulmonary disease. A three-center study". Chest. 103 (3): 678–84. doi:10.1378/chest.103.3.678. PMID 8449051.
- ↑ Hamilton RA, Gordon T (1992). "Incidence and cost of hospital admissions secondary to drug interactions involving theophylline". Ann Pharmacother. 26 (12): 1507–11. doi:10.1177/106002809202601202. PMID 1482803.
- ↑ Hayes E, Moroz L, Pizzi L, Baxter J (2007). "A cost decision analysis of 4 tocolytic drugs". Am J Obstet Gynecol. 197 (4): 383.e1–6. doi:10.1016/j.ajog.2007.06.052. PMID 17904969.