Allergic conjunctivitis differential diagnosis: Difference between revisions
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! Diseases !! Clinical manifestations !! Para-clinical findings !! Gold standard !! Additional findings | ! Diseases !! Clinical manifestations !! Para-clinical findings !! Gold standard !! Additional findings | ||
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| [[Bacterial]] [[conjunctivitis]] || || Bilateral [[matting]] of the [[eyelids]] in the morning, [[Mucopurulent]] [[discharge]], [[conjunctival]] [[hyperemia]], no previous history of [[conjunctivitis]]<ref name="pmid15201195">{{cite journal| author=Rietveld RP, ter Riet G, Bindels PJ, Sloos JH, van Weert HC| title=Predicting bacterial cause in infectious conjunctivitis: cohort study on informativeness of combinations of signs and symptoms. | journal=BMJ | year= 2004 | volume= 329 | issue= 7459 | pages= 206-10 | pmid=15201195 | doi=10.1136/bmj.38128.631319.AE | pmc=487734 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15201195 }} </ref>|| [[Conjunctival]] [[cultures]] || [[Itching]] , [[burning]], [[serous]] or no [[discharge]]<ref name="pmid15201195">{{cite journal| author=Rietveld RP, ter Riet G, Bindels PJ, Sloos JH, van Weert HC| title=Predicting bacterial cause in infectious conjunctivitis: cohort study on informativeness of combinations of signs and symptoms. | journal=BMJ | year= 2004 | volume= 329 | issue= 7459 | pages= 206-10 | pmid=15201195 | doi=10.1136/bmj.38128.631319.AE | pmc=487734 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15201195 }} </ref> | | [[Bacterial]] [[conjunctivitis]] || || Bilateral [[matting]] of the [[eyelids]] in the morning, [[Mucopurulent]] [[discharge]], [[conjunctival]] [[hyperemia]], no previous history of [[conjunctivitis]]<ref name="pmid15201195">{{cite journal| author=Rietveld RP, ter Riet G, Bindels PJ, Sloos JH, van Weert HC| title=Predicting bacterial cause in infectious conjunctivitis: cohort study on informativeness of combinations of signs and symptoms. | journal=BMJ | year= 2004 | volume= 329 | issue= 7459 | pages= 206-10 | pmid=15201195 | doi=10.1136/bmj.38128.631319.AE | pmc=487734 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15201195 }} </ref>||- || [[Conjunctival]] [[cultures]] || [[Itching]] , [[burning]], [[serous]] or no [[discharge]]<ref name="pmid15201195">{{cite journal| author=Rietveld RP, ter Riet G, Bindels PJ, Sloos JH, van Weert HC| title=Predicting bacterial cause in infectious conjunctivitis: cohort study on informativeness of combinations of signs and symptoms. | journal=BMJ | year= 2004 | volume= 329 | issue= 7459 | pages= 206-10 | pmid=15201195 | doi=10.1136/bmj.38128.631319.AE | pmc=487734 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15201195 }} </ref> | ||
|- | |- | ||
| [[Viral]] [[conjunctivitis]] || Thin, watery [[discharge]] with intensely [[hyperemic]] response<ref name="pmid24150468">{{cite journal| author=Azari AA, Barney NP| title=Conjunctivitis: a systematic review of diagnosis and treatment. | journal=JAMA | year= 2013 | volume= 310 | issue= 16 | pages= 1721-9 | pmid=24150468 | doi=10.1001/jama.2013.280318 | pmc=4049531 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24150468 }} </ref>, [[periauricular]] [[lymphadenopathy]]<ref name="pmid18249256">{{cite journal| author=Mahmood AR, Narang AT| title=Diagnosis and management of the acute red eye. | journal=Emerg Med Clin North Am | year= 2008 | volume= 26 | issue= 1 | pages= 35-55, vi | pmid=18249256 | doi=10.1016/j.emc.2007.10.002 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18249256 }} </ref> ||- || [[Viral]] [[cell]] [[cultures]], [[PCR]] for [[viral]] [[DNA]] detection<ref name="pmid10845603">{{cite journal| author=Elnifro EM, Cooper RJ, Klapper PE, Yeo AC, Tullo AB| title=Multiplex polymerase chain reaction for diagnosis of viral and chlamydial keratoconjunctivitis. | journal=Invest Ophthalmol Vis Sci | year= 2000 | volume= 41 | issue= 7 | pages= 1818-22 | pmid=10845603 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10845603 }} </ref> || - | | [[Viral]] [[conjunctivitis]] || Thin, watery [[discharge]] with intensely [[hyperemic]] response<ref name="pmid24150468">{{cite journal| author=Azari AA, Barney NP| title=Conjunctivitis: a systematic review of diagnosis and treatment. | journal=JAMA | year= 2013 | volume= 310 | issue= 16 | pages= 1721-9 | pmid=24150468 | doi=10.1001/jama.2013.280318 | pmc=4049531 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24150468 }} </ref>, [[periauricular]] [[lymphadenopathy]]<ref name="pmid18249256">{{cite journal| author=Mahmood AR, Narang AT| title=Diagnosis and management of the acute red eye. | journal=Emerg Med Clin North Am | year= 2008 | volume= 26 | issue= 1 | pages= 35-55, vi | pmid=18249256 | doi=10.1016/j.emc.2007.10.002 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18249256 }} </ref> ||- || [[Viral]] [[cell]] [[cultures]], [[PCR]] for [[viral]] [[DNA]] detection<ref name="pmid10845603">{{cite journal| author=Elnifro EM, Cooper RJ, Klapper PE, Yeo AC, Tullo AB| title=Multiplex polymerase chain reaction for diagnosis of viral and chlamydial keratoconjunctivitis. | journal=Invest Ophthalmol Vis Sci | year= 2000 | volume= 41 | issue= 7 | pages= 1818-22 | pmid=10845603 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10845603 }} </ref> || - | ||
Revision as of 17:34, 22 August 2022
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Overview
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References
- ↑ 1.0 1.1 Rietveld RP, ter Riet G, Bindels PJ, Sloos JH, van Weert HC (2004). "Predicting bacterial cause in infectious conjunctivitis: cohort study on informativeness of combinations of signs and symptoms". BMJ. 329 (7459): 206–10. doi:10.1136/bmj.38128.631319.AE. PMC 487734. PMID 15201195.
- ↑ Azari AA, Barney NP (2013). "Conjunctivitis: a systematic review of diagnosis and treatment". JAMA. 310 (16): 1721–9. doi:10.1001/jama.2013.280318. PMC 4049531. PMID 24150468.
- ↑ Mahmood AR, Narang AT (2008). "Diagnosis and management of the acute red eye". Emerg Med Clin North Am. 26 (1): 35–55, vi. doi:10.1016/j.emc.2007.10.002. PMID 18249256.
- ↑ Elnifro EM, Cooper RJ, Klapper PE, Yeo AC, Tullo AB (2000). "Multiplex polymerase chain reaction for diagnosis of viral and chlamydial keratoconjunctivitis". Invest Ophthalmol Vis Sci. 41 (7): 1818–22. PMID 10845603.
| Diseases | Clinical manifestations | Para-clinical findings | Gold standard | Additional findings | |
|---|---|---|---|---|---|
| Bacterial conjunctivitis | Bilateral matting of the eyelids in the morning, Mucopurulent discharge, conjunctival hyperemia, no previous history of conjunctivitis[1] | - | Conjunctival cultures | Itching , burning, serous or no discharge[1] | |
| Viral conjunctivitis | Thin, watery discharge with intensely hyperemic response[2], periauricular lymphadenopathy[3] | - | Viral cell cultures, PCR for viral DNA detection[4] | - | |
| Fanconi Bickel syndrome | Hepatomegaly, glucose and galactose intolerance, severe growth retardation | Hyperlipidemia, tubular nephropathy | Mutation analysis of SLC2A2 gene encoding GLUT2 transporter | Genu varum, hypophosphatemic rickets, Fanconi syndrome | |
| Glucose-6-phosphate dehydrogenase deficiency | Severe neonatal jaundice | Acute hemolytic anemia after certain infections, intake of some drugs or fava beans | Fluorescent spot test | Kernicterus , rhabdomyolysis |