Allergic conjunctivitis laboratory findings: Difference between revisions
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==Laboratory findings== | ==Laboratory findings== | ||
===[[Skin]] [[prick]] test=== | ===[[Skin]] [[prick]] test=== | ||
[[Intradermal]] [[injections]] of [[individual allergens]] are administered to detect [[sensitivity]]<ref name="pmid23497516">{{cite journal| author=La Rosa M, Lionetti E, Reibaldi M, Russo A, Longo A, Leonardi S | display-authors=etal| title=Allergic conjunctivitis: a comprehensive review of the literature. | journal=Ital J Pediatr | year= 2013 | volume= 39 | issue= | pages= 18 | pmid=23497516 | doi=10.1186/1824-7288-39-18 | pmc=3640929 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23497516 }} </ref>. | *[[Intradermal]] [[injections]] of [[individual allergens]] are administered to detect [[sensitivity]]<ref name="pmid23497516">{{cite journal| author=La Rosa M, Lionetti E, Reibaldi M, Russo A, Longo A, Leonardi S | display-authors=etal| title=Allergic conjunctivitis: a comprehensive review of the literature. | journal=Ital J Pediatr | year= 2013 | volume= 39 | issue= | pages= 18 | pmid=23497516 | doi=10.1186/1824-7288-39-18 | pmc=3640929 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23497516 }} </ref>. | ||
* It is a highly sensitive test [37]. | |||
*The result is considered positive when the resulting [[wheal]] is at least 3 mm larger than the negative control. [[Systemic]] reactions are rare.[38]. | |||
===[[IgE]] estimation=== | ===[[IgE]] estimation=== | ||
[[In-vitro]] tests to detect [[IgE]] [[antibodies]] to specific [[allergens]] are widely used<ref name="pmid29996875">{{cite journal| author=Arasi S, Corsello G, Villani A, Pajno GB| title=The future outlook on allergen immunotherapy in children: 2018 and beyond. | journal=Ital J Pediatr | year= 2018 | volume= 44 | issue= 1 | pages= 80 | pmid=29996875 | doi=10.1186/s13052-018-0519-4 | pmc=6042356 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29996875 }} </ref>. | [[In-vitro]] tests to detect [[IgE]] [[antibodies]] to specific [[allergens]] are widely used<ref name="pmid29996875">{{cite journal| author=Arasi S, Corsello G, Villani A, Pajno GB| title=The future outlook on allergen immunotherapy in children: 2018 and beyond. | journal=Ital J Pediatr | year= 2018 | volume= 44 | issue= 1 | pages= 80 | pmid=29996875 | doi=10.1186/s13052-018-0519-4 | pmc=6042356 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29996875 }} </ref>. | ||
Revision as of 03:55, 30 August 2022
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Overview
Allergic conjunctivitis is usually a clinical diagnosis. Laboratory tests are primarily supportive. They may help in differentiating intrinsic and extrinsic forms of the condition and thus, guide the treatment.
Laboratory findings
Skin prick test
- Intradermal injections of individual allergens are administered to detect sensitivity[1].
- It is a highly sensitive test [37].
- The result is considered positive when the resulting wheal is at least 3 mm larger than the negative control. Systemic reactions are rare.[38].
IgE estimation
In-vitro tests to detect IgE antibodies to specific allergens are widely used[2].
References
- ↑ La Rosa M, Lionetti E, Reibaldi M, Russo A, Longo A, Leonardi S; et al. (2013). "Allergic conjunctivitis: a comprehensive review of the literature". Ital J Pediatr. 39: 18. doi:10.1186/1824-7288-39-18. PMC 3640929. PMID 23497516.
- ↑ Arasi S, Corsello G, Villani A, Pajno GB (2018). "The future outlook on allergen immunotherapy in children: 2018 and beyond". Ital J Pediatr. 44 (1): 80. doi:10.1186/s13052-018-0519-4. PMC 6042356. PMID 29996875.