Alpha-4 beta-2 nicotinic receptor: Difference between revisions
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Latest revision as of 14:16, 4 September 2012
Overview
The alpha-4 beta-2 nicotinic receptor ((α4)2(β2)3) is a type of nicotinic acetylcholine receptor, consisting of α4 and β2 subunits[1].
It is located in the brain, where activation yields post- and presynaptic excitation[1], mainly by increased Na+ and K+ permeability.
Agonists
Nicotinic agonists for this receptor include:
Antagonists
- mecamylamine
- methylaconitine
- α-conotoxin